Catalog No.
YHE62501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly19-Glu184
Predicted molecular weight
20.70 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49069
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CAML, Calcium signal-modulating cyclophilin ligand, CAMLG
Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes., PMID:40053464
Characterizing Genetic-Predisposed Proteins Involving Insomnia by Integrating Genome-Wide Association Study Summary Statistics., PMID:39827250
Proteomic analysis of Biliverdin protected cerebral ischemia-reperfusion injury in rats., PMID:37993477
Application of genetic risk score for in-stent restenosis of second- and third-generation drug-eluting stents in geriatric patients., PMID:37468836
Identifying novel genes for amyotrophic lateral sclerosis by integrating human brain proteomes with genome-wide association data., PMID:37148340
Preparation and Preliminary Application of Epitope Peptide-Based Antibody against Toxoplasma gondii GRA3., PMID:36977144
CAMLG-CDG: a novel congenital disorder of glycosylation linked to defective membrane trafficking., PMID:35262690
The WRB Subunit of the Get3 Receptor is Required for the Correct Integration of its Partner CAML into the ER., PMID:31417168
Modulation of intracellular calcium signaling by microRNA-34a-5p., PMID:30262862
Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum., PMID:30154321
TMUB1 Inhibits BRL-3A Hepatocyte Proliferation by Interfering with the Binding of CAML to Cyclophilin B through its TM1 Hydrophobic Domain., PMID:29967478
Tail-anchored Protein Insertion in Mammals: FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR., PMID:27226539
Region-Specific Vulnerability to Oxidative Stress, Neuroinflammation, and Tau Hyperphosphorylation in Experimental Diabetes Mellitus Mice., PMID:26923011
Emery-Dreifuss muscular dystrophy mutations impair TRC40-mediated targeting of emerin to the inner nuclear membrane., PMID:26675233
Differential induction of plasma cells by isoforms of human TACI., PMID:25631768
Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6., PMID:25225460
A novel interaction between calcium-modulating cyclophilin ligand and Basigin regulates calcium signaling and matrix metalloproteinase activities in human melanoma cells., PMID:23879967
Type IV pilus protein PilA of Pseudomonas aeruginosa modulates calcium signaling through binding the calcium-modulating cyclophilin ligand., PMID:23266901
Molecular machinery for insertion of tail-anchored membrane proteins into the endoplasmic reticulum membrane in mammalian cells., PMID:23041287
IL-6 induction of hepatocyte proliferation through the Tmub1-regulated gene pathway., PMID:22426572
Dengue virus utilizes calcium modulating cyclophilin-binding ligand to subvert apoptosis., PMID:22281498
CAML promotes prolactin-dependent proliferation of breast cancer cells by facilitating prolactin receptor signaling pathways., PMID:21128111
Transmembrane and ubiquitin-like domain containing 1 (Tmub1) regulates locomotor activity and wakefulness in mice and interacts with CAMLG., PMID:20582322
RNF122: a novel ubiquitin ligase associated with calcium-modulating cyclophilin ligand., PMID:20553626
CAML does not modulate tetherin-mediated restriction of HIV-1 particle release., PMID:20126395
Interactions of viral protein U (Vpu) with cellular factors., PMID:20012522
Effect of calcium-modulating cyclophilin ligand on human immunodeficiency virus type 1 particle release and cell surface expression of tetherin., PMID:19793820
MUC1 mucin interacts with calcium-modulating cyclophilin ligand., PMID:19135167
Interaction between parasitophorous vacuolar membrane-associated GRA3 and calcium modulating ligand of host cell endoplasmic reticulum in the parasitism of Toxoplasma gondii., PMID:19127325
[Retroposons of Alu family from cis-regulatory modules of DNAse II and CAML genes effect gene expression in A549 and HEK293 cells]., PMID:18664127
Identification of calcium-modulating cyclophilin ligand as a human host restriction to HIV-1 release overcome by Vpu., PMID:18500349
[Screening and identification of proteins interacting with HCV NS4A via yeast double hybridization in leukocytes and gene cloning of the interacting protein]., PMID:17429534
Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling., PMID:16243292
Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation., PMID:15668245
CAML is required for efficient EGF receptor recycling., PMID:12919676
Kaposi's sarcoma-associated herpesvirus mitochondrial K7 protein targets a cellular calcium-modulating cyclophilin ligand to modulate intracellular calcium concentration and inhibit apoptosis., PMID:12388711
Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis., PMID:12031912
Cloning of rat calcium-modulating cyclophilin ligand., PMID:11762198
A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth., PMID:11104810
Co-localization of calcium-modulating cyclophilin ligand with intracellular calcium pools., PMID:9632697
NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily., PMID:9311921
A hydrophobic domain of Ca2+-modulating cyclophilin ligand modulates calcium influx signaling in T lymphocytes., PMID:8621480
The gene for calcium-modulating cyclophilin ligand (CAMLG) is located on human chromosome 5q23 and a syntenic region of mouse chromosome 13., PMID:8824814
Cloning of the gene encoding the mouse homologue of the human calcium signal-modulating ligand., PMID:7590290
Calcium signalling in T cells stimulated by a cyclophilin B-binding protein., PMID:7522304
For research use only. Not for human or drug use.
