Catalog No.
YHE62401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys201-Lys461
Predicted molecular weight
30.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P49023
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Paxillin, PXN
Tbx1 plays a critical role in focal adhesion dynamics through paxillin regulation., PMID:40441895
A genome-wide base-editing screen uncovers a pivotal role of paxillin δ ubiquitination in influenza virus infection., PMID:40434888
Influence of feeding systems on the microbial community and flavor characteristics of raw milk: A comparative analysis., PMID:40043765
Remodeling of extracellular matrix collagen IV by MIG-6/papilin regulates neuronal architecture., PMID:39990436
Remodeling of extracellular matrix collagen IV by MIG-6/papilin regulates neuronal architecture., PMID:39989960
Conformational dynamics and multi-modal interaction of Paxillin with the Focal Adhesion Targeting Domain., PMID:39803547
A feedback loop between Paxillin and Yorkie sustains Drosophila intestinal homeostasis and regeneration., PMID:39794306
Bioinformatics analysis reveals VEGFC's prognostic significance in head and neck squamous cell carcinoma and its association with immune cell infiltration., PMID:39697755
Paraxanthine enhances memory and neuroplasticity more than caffeine in rats., PMID:39617850
Novel biomarkers associated with oxidative stress and immune infiltration in intervertebral disc degeneration based on bioinformatics approaches., PMID:39182249
Identifying the key hub genes linked with lung squamous cell carcinoma by examining the differentially expressed and survival genes., PMID:39097557
CXCL5 impedes CD8+ T cell immunity by upregulating PD-L1 expression in lung cancer via PXN/AKT signaling phosphorylation and neutrophil chemotaxis., PMID:39034411
Evaluation of Paxillin Expression in Odontogenic Cysts and Tumors., PMID:38962075
Targeted serum proteome profiling reveals nicotinamide adenine dinucleotide phosphate (NADPH)-related biomarkers to discriminate linear IgA bullous disorder from dermatitis herpetiformis., PMID:38908771
Plexin D1 negatively regulates macrophage-derived foam cell migration via the focal adhesion kinase/Paxillin pathway., PMID:38897039
Kaempferol-Enhanced Migration and Differentiation of C2C12 Myoblasts via ITG1B/FAK/Paxillin and IGF1R/AKT/mTOR Signaling Pathways., PMID:38860356
A comparative analysis of paxillin and Hic-5 proximity interactomes., PMID:38801098
Paxillin regulates androgen receptor expression associated with granulosa cell focal adhesions., PMID:38718206
Reversine inhibits proliferation and induces apoptosis of human osteosarcoma cells through targeting MEK1., PMID:38706714
Adenosine kinase inhibits β-cell proliferation by upregulating DNA methyltransferase 3A expression., PMID:38699782
Phosphatidylinositol 4-Kinase III Alpha Governs Cytoskeletal Organization for Invasiveness of Liver Cancer Cells., PMID:38636680
Kaempferol 3-O-Rutinoside, a Flavone Derived from Tetrastigma hemsleyanum Diels et Gilg, Reduces Body Temperature through Accelerating the Elimination of IL-6 and TNF-α in a Mouse Fever Model., PMID:38611918
Erucin, a natural isothiocyanate, exerts pro-angiogenic properties in cultured endothelial cells and reverts angiogenic impairment induced by high glucose., PMID:38488442
Paxillin phase separation promotes focal adhesion assembly and integrin signaling., PMID:38466167
Role of steroid hormones in the maintenance of focal adhesions in bovine oviductal epithelial cells., PMID:38433026
Phytol and α-Bisabolol Synergy Induces Autophagy and Apoptosis in A549 Cells and Additional Molecular Insights through Comprehensive Proteome Analysis via Nano LC-MS/MS., PMID:38415491
ICAM-1 Deletion Using CRISPR/Cas9 Protects the Brain from Traumatic Brain Injury-Induced Inflammatory Leukocyte Adhesion and Transmigration Cascades by Attenuating the Paxillin/FAK-Dependent Rho GTPase Pathway., PMID:38326036
Effect of Paxillin Expression and Phosphorylation on Colorectal Cancer Prognosis and Metastasis., PMID:38307570
An autophagy-independent role of ULK1/ULK2 in mechanotransduction and breast cancer cell migration., PMID:38163960
C5 methylation confers accessibility, stability and selectivity to picrotoxinin., PMID:38097583
Peroxidasin is required for full viability in development and for maintenance of tissue mechanics in adults., PMID:38000777
Fyn-Mediated Paxillin Tyrosine 31 Phosphorylation Regulates Migration and Invasion of Breast Cancer Cells., PMID:37958964
An ULK1/2-PXN mechanotransduction pathway suppresses breast cancer cell migration., PMID:37846507
TATA-box-binding protein promotes hepatocellular carcinoma metastasis through epithelial-mesenchymal transition., PMID:37314767
Autophagy-related gene PXN as a prognostic marker: Promotion of ovarian cancer progression by suppressing the p110β/Vps34/Beclin1 pathway., PMID:37232085
Circular RNA circRILPL1 promotes nasopharyngeal carcinoma malignant progression by activating the Hippo-YAP signaling pathway., PMID:37173390
Angiopoietin-like 4 induces head and neck squamous cell carcinoma cell migration through the NRP1/ABL1/PXN pathway., PMID:37169211
Upregulation of MAPKAPK5-AS1, PXN-AS1 and URB1-AS1 lncRNAs in non-functioning pituitary adenoma., PMID:37154079
Integration of Transcriptomics and Non-Targeted Metabolomics Reveals the Underlying Mechanism of Skeletal Muscle Development in Duck during Embryonic Stage., PMID:36982289
Analysis of Communal Molecular Mechanism Between Chronic Obstructive Pulmonary Disease and Osteoporosis., PMID:36937804
Prognostic Value of CAV1 and CAV2 in Head and Neck Squamous Cell Carcinoma., PMID:36830672
Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer Cells., PMID:36674696
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat., PMID:36657700
Basigin is necessary for normal decidualization of human uterine stromal cells., PMID:36303457
Pan-Cancer Analysis on the Oncogenic Role of Programmed Cell Death 10., PMID:36276268
LncRNA FIRRE promotes the proliferation and metastasis of hepatocellular carcinoma by regulating the expression of PXN through interacting with MBNL3., PMID:35988459
ITGβ6 Facilitates Skeletal Muscle Development by Maintaining the Properties and Cytoskeleton Stability of Satellite Cells., PMID:35888016
Identification of Paxillin as a Prognostic Factor for Glioblastoma via Integrated Bioinformatics Analysis., PMID:35782068
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid., PMID:35751199
Screening the Potential Biomarkers of COVID-19-Related Thrombosis Through Bioinformatics Analysis., PMID:35692833
For research use only. Not for human or drug use.
