Catalog No.
YHE59402
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys19-Val148
Predicted molecular weight
17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P48594
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Peptidase inhibitor 11, PI11, SCCA-2, SERPINB4, Serpin B4, Squamous cell carcinoma antigen 2, Leupin, SCCA2, PI-11
TRIM29 upregulation contributes to chemoresistance in triple negative breast cancer via modulating S100P-β-catenin axis., PMID:40420099
Splenic comparative transcriptome analysis reveals the immunological mode of undomesticated Gayal (Bos frontalis) for adapting to harsh environments., PMID:40394466
The role of squamous cell carcinoma antigen and cytokeratin 19 fragment in predicting the outcome of esophageal cancer patients: insights from a meta-analysis., PMID:40259318
Utility of circulating human papillomavirus DNA as a biomarker for detection and prognosis of cervical cancer in Japanese patients., PMID:40257655
Role of SCCA and CYFRA 21-1 in the differential diagnosis of sinonasal benign and malignant diseases., PMID:39971650
Comparison of two automated immunoassays for quantifying ProGRP, SCC and HE4 in serum: impact on diagnostic accuracy., PMID:39954248
SERPINH1 secretion by cancer-associated fibroblasts promotes hepatocellular carcinoma malignancy through SENP3-mediated SP1/SQLE pathway., PMID:39946769
The SERPINB4 gene mutation identified in twin patients with Crohn's disease impaires the intestinal epithelial cell functions., PMID:39838210
Affinity Peptide-Based Circularly Permuted Fluorescent Protein Biosensors for Non-Small Cell Lung Cancer Diagnosis., PMID:39771637
Predictive factors for failure of neoadjuvant docetaxel, cisplatin, and 5-fluorouracil therapy in esophageal squamous cell carcinoma., PMID:39696976
Prognostic Impact of Squamous Cell Carcinoma Antigen During Neoadjuvant Chemotherapy for Patients With Esophageal Squamous Cell Carcinoma Treated With Minimally Invasive Esophagectomy., PMID:39626938
Evaluation of Amide Proton Transfer Imaging Combined With Serum Squamous Cell Carcinoma Antigen for Grading Cervical Cancer., PMID:39582402
SCCA and CYFRA 21-1 Reference Intervals for Apparently Healthy Chinese Adults: a Multicenter Cross-Sectional Study., PMID:39506597
Roles of microRNA-486-5p in the diagnosis and the association with clinical symptoms of cervical cancer., PMID:39417317
Combining serum CDK1 with tumor markers for the diagnosis of small cell lung cancer., PMID:39397200
Ultrasensitive detection of SCCA employing a graphene oxide integrated microfiber ring laser biosensor., PMID:39276440
Icariin ameliorates TNF-α/IFN-γ-induced oxidative stress, inflammatory response and apoptosis of human immortalized epidermal cells through the WTAP/SERPINB4 axis., PMID:39177922
Comprehensive assessment of postoperative recurrence and survival in patients with cervical cancer., PMID:39116515
Comparison of two platinum-containing chemotherapy regimens in the treatment of advanced cervical cancer with concurrent chemoradiotherapy., PMID:39092860
[Expression and clinical significance of serum squamous cell carcinoma antigen（SCCAg） in sinonasal inverted papilloma]., PMID:38973041
Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory., PMID:38892277
Trajectories of squamous cell carcinoma antigen and outcomes of patients with advanced penile cancer after chemotherapy based on paclitaxel, ifosfamid, and cisplatin regimen., PMID:38888362
Diagnostic potential of protein serum biomarkers for distinguishing small and non-small cell lung cancer in patients with suspicious lung lesions., PMID:38804910
SERPINB3/B4 Is Increased in Psoriasis and Rosacea Lesions and Has Proinflammatory Effects in Mouse Models of these Diseases., PMID:38735363
The optimal threshold for squamous-cell carcinoma antigen to predict lymph node metastasis in early-stage cervical squamous-cell carcinoma., PMID:38714404
Accuracy of surveillance serum squamous cell carcinoma antigen for cervical cancer recurrence after definitive chemoradiation., PMID:38684343
Clinical Significance of Serum SCC Levels Before Treatment for Locally Advanced Cervical Squamous Cell Carcinoma., PMID:38677756
Application Value of CYFRA21-1 Combined with NSE, CEA, and SCC-Ag in Lung Cancer., PMID:38623667
Average log change rate of pretreatment squamous cell carcinoma antigen after concurrent chemoradiotherapy in stage IIIC1 cervical squamous cell carcinoma., PMID:38622276
Prognostic Impact of Serum SCC Antigen in the 566 Upfront Surgery Group of Esophageal Squamous Cell Carcinoma: A Multi-Institutional Study of the Japan Esophageal Society., PMID:38583987
Use of tumor markers in distinguishing lung adenocarcinoma-associated malignant pleural effusion from tuberculous pleural effusion., PMID:38583522
Integrated pretreatment diffusion kurtosis imaging and serum squamous cell carcinoma antigen levels: a biomarker strategy for early assessment of radiotherapy outcomes in cervical cancer., PMID:38536425
Clinical Efficacy of Sodium Cantharidate Vitamin B6 Combined with Concurrent Chemoradiotherapy in the Treatment of Local Advanced Cervical Cancer and its Influence on Tumor Markers., PMID:38466067
Correlation of serum level of squamous cell carcinoma antigen with severity of cutaneous psoriasis, assessed using the simplified psoriasis index., PMID:38422600
Serum squamous cell carcinoma antigen level and magnetic resonance imaging for the prognosis of locally advanced cervical cancer., PMID:38305609
Exploring the comorbidity mechanisms between psoriasis and obesity based on bioinformatics., PMID:38279589
Serum CYFRA21-1 and SCC-Ag levels in women during pregnancy and their diagnostic value for cervical cancer., PMID:38198984
Diagnostic value of serum squamous cell carcinoma antigen and cytokeratin fragment antigen 21-1 for sinonasal inverted papilloma: an exploratory study., PMID:38189590
Extracellular vesicle-derived TP53BP1, CD34, and PBX1 from human peripheral blood serve as potential biomarkers for the assessment and prediction of vascular aging., PMID:38173016
The polymorphic variant of SerpinB3 (SerpinB3-PD) is associated with faster cirrhosis decompensation., PMID:37990490
SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer., PMID:37980563
Clinical Value Analysis of Serum TK1, SCC-Ag, and MUC-1 in the Diagnosis and Prognosis Evaluation of Cervical Cancer., PMID:37708549
Impact of anti-squamous cell carcinoma antigen antibodies on serum squamous cell carcinoma antigen levels measured by chemiluminescent immunoassay and chemiluminescent enzyme immunoassay., PMID:37706549
Squamous Cell Carcinoma Antigen in the Follow-up of Patients With Head and Neck Cancer., PMID:37694613
IL-22-Induced Ubiquitin-Specific Protease 15 Promotes Proliferation and Inflammation of Keratinocytes through Stabilization of Squamous Cell Carcinoma Antigen 2., PMID:37517516
SCCA1/SERPINB3 suppresses antitumor immunity and blunts therapy-induced T cell responses via STAT-dependent chemokine production., PMID:37279067
Bioinformatic Analysis of the Potential Common Pathogenic Mechanisms for Psoriasis and Metabolic Syndrome., PMID:37222907
Correlation between HRCT signs and levels of CA125, SCCA, and NSE for different pathological types of lung cancer., PMID:37203842
Study on the preoperative value of serum SCC-Ag in predicting the stromal invasion of cervical squamous cell carcinoma., PMID:37184678
An electrochemiluminescence immunosensor with double co-reaction accelerators based on Ag3PO4@EuPO4-AgNP for detecting squamous cell carcinoma antigen., PMID:37184586
For research use only. Not for human or drug use.
