Catalog No.
YHE56801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln23-Asn166
Predicted molecular weight
18.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P48304
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PSP-2, REG-1-beta, REGL, REG1B, Regenerating islet-derived protein 1-beta, Pancreatic stone protein 2, Regenerating protein I beta, Lithostathine-1-beta, PSPS2
An Integrative Analysis of Transcriptome Combined with Machine Learning and Single-Cell RNA-Seq for the Common Biomarkers in Crohn's Disease and Kidney Stone Disease., PMID:40242727
A Clinical Laboratory Improvement Amendments/College of American Pathologists-Compliant Noninvasive Laboratory-Developed Test for Early Detection of Pancreatic Ductal Adenocarcinoma., PMID:39521243
Evaluation of urinary C-reactive protein as an early detection biomarker for pancreatic ductal adenocarcinoma., PMID:39309742
Identification of biomarkers and potential therapeutic targets for pancreatic cancer by proteomic analysis in two prospective cohorts., PMID:38754433
A Multiplexed Urinary Biomarker Panel Has Potential for Alzheimer's Disease Diagnosis Using Targeted Proteomics and Machine Learning., PMID:37762058
Interdependencies of Gene Expression and Function between Two Redox Enzymes and REG Family Proteins in Murine Pancreatic Islets and Human Pancreatic Cells., PMID:37107224
Evaluation of transcriptomic molecular classification, biological behavior, and clinicopathological features in hepatocellular carcinoma., PMID:36655856
Urine biomarkers enable pancreatic cancer detection up to 2 years before diagnosis., PMID:36093581
Lack of Associations between Environmental Exposures and Environmental Enteric Dysfunction among 18-Month-Old Children in Rural Malawi., PMID:36078607
Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation., PMID:36002022
Infection With Escherichia Coli Pathotypes Is Associated With Biomarkers of Gut Enteropathy and Nutritional Status Among Malnourished Children in Bangladesh., PMID:35873159
Correlation of REG1A, Claudin 7 and Ki67 expressions with tumor recurrence and prognostic factors in superficial urothelial urinary bladder carcinomas., PMID:35435371
Provision of small-quantity lipid-based nutrient supplements does not improve intestinal health among rural Malawian children., PMID:35128820
Identification of diagnostic signatures in ulcerative colitis patients via bioinformatic analysis integrated with machine learning., PMID:34731452
Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study., PMID:34697034
Association of lipocalin-2 and low-density lipoprotein receptor-related protein-1 (LRP1) with biomarkers of environmental enteric dysfunction (EED) among under 2 children in Bangladesh: results from a community-based intervention study., PMID:34423140
The Potential Role of REG Family Proteins in Inflammatory and Inflammation-Associated Diseases of the Gastrointestinal Tract., PMID:34281249
A combination of urinary biomarker panel and PancRISK score for earlier detection of pancreatic cancer: A case-control study., PMID:33301466
Faecal regenerating 1B protein concentration is not associated with child growth in rural Malawi., PMID:33112481
Identification of key genes and pathways in gastric signet ring cell carcinoma based on transcriptome analysis., PMID:32149050
Development of PancRISK, a urine biomarker-based risk score for stratified screening of pancreatic cancer patients., PMID:31857725
Bioinformatics Tools and Workflow to Select Blood Biomarkers for Early Cancer Diagnosis: An Application to Pancreatic Cancer., PMID:31538697
Pathobiome driven gut inflammation in Pakistani children with Environmental Enteric Dysfunction., PMID:31442248
MicroRNA-7 directly targets Reg1 in pancreatic cells., PMID:31166710
Candidate genes involved in metastasis of colon cancer identified by integrated analysis., PMID:30884206
Genome-wide DNA Methylation in Treatment-naïve Ulcerative Colitis., PMID:30137272
Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes., PMID:28877242
Reg2 Expression Is Required for Pancreatic Islet Compensation in Response to Aging and High-Fat Diet-Induced Obesity., PMID:28009527
Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma., PMID:27788482
Prognostic role of regenerating gene-I in patients with stage-IV head and neck squamous cell carcinoma., PMID:27539087
Small Intestine Bacterial Overgrowth and Environmental Enteropathy in Bangladeshi Children., PMID:26758185
Regenerating gene 1B silencing inhibits colon cancer cell HCT116 proliferation and invasion., PMID:25768000
Synergistic activations of REG I α and REG I β promoters by IL-6 and Glucocorticoids through JAK/STAT pathway in human pancreatic β cells., PMID:25767811
Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis., PMID:24328148
Validation of four candidate pancreatic cancer serological biomarkers that improve the performance of CA19.9., PMID:24007603
REG1B as a predictor of childhood stunting in Bangladesh and Peru., PMID:23553156
REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation., PMID:23519454
DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?, PMID:22498030
Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases., PMID:22488912
The expression of REG 1A and REG 1B is increased during acute amebic colitis., PMID:21586335
Familiar Meniere's disease restricted to 1.48 Mb on chromosome 12p12.3 by allelic and haplotype association., PMID:20927121
Regenerating gene I regulates interleukin-6 production in squamous esophageal cancer cells., PMID:20056108
Gene expression profiles of late colonic Crohn's disease., PMID:18084881
Protein-X, Pancreatic Stone-, Pancreatic thread-, reg-protein, P19, lithostathine, and now what? Characterization, structural analysis and putative function(s) of the major non-enzymatic protein of pancreatic secretions., PMID:12369899
Analysis of the reg1alpha and reg1beta gene transcripts in patients with fibrocalculous pancreatopathy., PMID:12236439
No abnormalities of reg1 alpha and reg1 beta gene associated with diabetes mellitus., PMID:11796176
Preferential expression of reg I beta gene in human adult pancreas., PMID:11396963
Identification of a novel Reg family gene, Reg IIIdelta, and mapping of all three types of Reg family gene in a 75 kilobase mouse genomic region., PMID:10767532
The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic beta-cells., PMID:10526060
Specific reg II gene overexpression in the non-obese diabetic mouse pancreas during active diabetogenesis., PMID:9373186
For research use only. Not for human or drug use.
