Catalog No.
YHE45801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr26-Ile321
Predicted molecular weight
36.22 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P45983
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MAP kinase 8, JNK1, SAPK1C, Stress-activated protein kinase 1c, Mitogen-activated protein kinase 8, SAPK1, c-Jun N-terminal kinase 1, SAPK1c, MAPK8, Stress-activated protein kinase JNK1, PRKM8, JNK-46, MAPK 8
Mechanism of Huoshan large-leaf yellow tea in treatment of diabetic cognitive dysfunction based on bioinformatics and network pharmacology., PMID:40505484
MAPK8 and HDAC6: potential biomarkers related to autophagy in diabetic retinopathy based on bioinformatics analysis., PMID:40469433
Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer., PMID:40468448
JNK1 in SF1 neurons regulates the central action of thyroid hormones on hepatic lipid metabolism., PMID:40419019
WDR62 affects the progression of ovarian cancer by regulating the cell cycle., PMID:40369663
Asarum heterotropoides F. schmidt attenuates osteoarthritis via multi-target anti-inflammatory actions: A network pharmacology and experimental validation., PMID:40345271
Mechanism of Ershen Zhenwu Decoction in ameliorating chronic heart failure via JNK/MAPK-regulated apoptosis: insights from network pharmacology and experimental validation., PMID:40329967
Rituximab-Chidamide combination chemotherapy enhances autophagy to overcome drug resistance in diffuse large B-cell lymphoma., PMID:40258315
Characterization of two novel angiotensin converting enzyme-inhibitory peptides from yellow tuna peptides: Inhibitory mechanism, transport route and network pharmacology analysis., PMID:40253180
Equipotent bisphenol S and bisphenol F with widely differing modes of action exhibit additive effects in immunotoxicity: insights based on intrinsic immunity, apoptosis and regeneration, and oxidative stress., PMID:40239502
Probing the molecular mechanism of kaempferol in relieving rheumatoid arthritis based on network pharmacology., PMID:40221466
Features of the Subpopulation Composition of Peripheral Blood T-Helpers in the Long-Term Period in Persons Exposed to Chronic Radiation In Utero., PMID:40216717
The key active ingredients identification and pharmacological mechanism investigation of extract of ethyl acetate from Er Miao San aganist rheumatoid arthritis., PMID:40204052
Huang-qin decoction alleviates deoxycholic acid-induced colorectal cancer in mice by regulating gut microbiota., PMID:40158829
Time restricted feeding with or without ketosis influences metabolism-related gene expression in a tissue-specific manner in aged rats., PMID:40153191
Rhoifolin Improves Glycometabolic Control in Streptozotocin-Induced Diabetic Rats by Up-Regulating the Expression of Insulin Signaling Proteins and Down-Regulating the MAPK/JNK Pathway., PMID:40143138
Construction of a novel gene signature linked to ferroptosis in pediatric sepsis., PMID:40070882
Identification of potential biomarkers associated with oxidative stress in the pathogenesis of pre-eclampsia., PMID:40068030
Liquiritin as a Tumor Suppressor Prevents the Development of Breast Cancer via the Epidermal Growth Factor Receptor/Mitogen-Activated Protein Kinase 8 Signaling Pathway., PMID:40014434
Assessing the Causal Relationship Between Plasma Proteins and Pulmonary Fibrosis: A Systematic Analysis Based on Mendelian Randomization., PMID:40001968
Transcriptomic profiles of single-cell autophagy-related genes (ATGs) in lung diseases., PMID:39920481
Naoxintong Is Involved in the Coagulation Regulation of Warfarin Through the MAPK Pathway., PMID:39906888
Mesoporous polymeric nanoparticles for effective treatment of inflammatory diseases: an in vivo study., PMID:39902477
Bioinformatics and Gene Expression Omnibus Analysis of Key Candidate Genes and Pathways Associated with Femoral Head Necrosis., PMID:39830663
Inactivation of glutathione S-transferase alpha 4 blocks Enterococcus faecalis-induced bystander effect by promoting macrophage ferroptosis., PMID:39819335
Exploring the potential mechanism of action of Wutou-Guizhi decoction in the treatment of rheumatoid arthritis through network pharmacology analysis., PMID:39765191
miR-193b-365 microcluster downstream of Fezf2 coordinates neuron-subtype identity and dendritic morphology in cortical projection neurons., PMID:39759000
Galangin promotes apoptosis by upregulating the pro-apoptotic gene BAX in triple-negative breast cancer., PMID:39702881
Curcumin Alleviates Arecoline-induced Oral Submucous Fibrosis via the FOSL1/MAPK8 Axis., PMID:39674970
Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of goutengsan on methamphetamine dependence., PMID:39669203
Identification and validation of a novel autophagy-related biomarker in obstructive sleep apnea syndrome., PMID:39665515
Comprehensive genome-wide identification and functional characterization of mapk gene family in northern snakeheads (Channa argus)., PMID:39645216
Different infant formulas can activate toll-like receptor 9 in vitro and inhibit interleukin 6 in human primary intestinal epithelial cells., PMID:39567370
Silencing PPAP2C inhibits lung adenocarcinoma migration and invasion via the ERK/JNK pathway., PMID:39540350
Network pharmacology and molecular docking to explore the potential molecular mechanism of chlorogenic acid treatment of oral squamous cell carcinoma., PMID:39533555
Qiang Jin Mixture Promotes Osteogenic Differentiation of MC3T3-E1 Cells via BMP2/Smads Pathway and its Network Pharmacology Study., PMID:39527391
Long Non-coding RNA TPRG1-AS1 Interacts With CLTC in Liver Cancer Cells., PMID:39477283
Network toxicology and molecular docking to investigative the non-acetylcholinesterase mechanisms and targets of cardiotoxicity injury induced by organophosphorus pesticides., PMID:39465796
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
Investigation of chromatin remodeling-related biomarkers and associated molecular mechanism in pulpitis., PMID:39433267
Epidermal Growth Factor Receptor Emerges as a Viable Target for Reducing Tumorigenicity of MDCK Cells., PMID:39336799
Ginkgo Biloba Bioactive Phytochemicals against Age-Related Diseases: Evidence from a Stepwise, High-Throughput Research Platform., PMID:39334763
Evodiamine inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells via the SRC/ERBB2-mediated MAPK/ERK signaling pathway., PMID:39334374
Pharmacological targets and validation of remdesivir for the treatment of COVID-19-associated pulmonary fibrosis: A network-based pharmacology and bioinformatics study., PMID:39331891
Network Pharmacology and in vitro Experimental Verification on Intervention of Oridonin on Non-Small Cell Lung Cancer., PMID:39331210
Effect of Methyl Glycoside on Apoptosis and Oxidative Stress in Hypoxia Induced-Reoxygenated H9C2 Cell Lines., PMID:39292425
Transcriptional Activity of Genes Regulating T-Helper Differentiation in the Accidentally Exposed Population of the Southern Urals., PMID:39283554
Bailixiang tea, an herbal medicine formula, co-suppresses TLR2/MAPK8 and TLR2/NF-κB signaling pathways to protect against LPS-triggered cytokine storm in mice., PMID:39265795
Andrographolide demonstrates anti-proliferative activity in oral cancer by promoting apoptosis, the programmed cell death process., PMID:39229580
Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Astragaloside Ⅳ in treating intervertebral disc degeneration., PMID:39214272
For research use only. Not for human or drug use.
