Catalog No.
YHE45301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro5-Val201
Predicted molecular weight
47.97 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P45877
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Peptidyl-prolyl cis-trans isomerase C, PPIC, Cyclophilin C, Rotamase C, PPIase C, CYPC
Machine learning algorithms integrate bulk and single-cell RNA data to reveal the crosstalk and heterogeneity of NOTCH and autophagy activity following idiopathic pulmonary fibrosis., PMID:40494203
SRPS: Survival Reinforced Transfer Learning for Multicentric Proteomic Subtyping and Biomarker Discovery., PMID:40493767
Ultrasound treatment on commercial pea protein isolates systems: Effect on structure, rheology and gelling properties., PMID:39520888
PPIC-labeled CAFs: Key players in neoadjuvant chemotherapy resistance for gastric cancer., PMID:39116799
Investigation of cross-opsonic effect leads to the discovery of PPIase-domain containing protein vaccine candidate to prevent infections by Gram-positive ESKAPE pathogens., PMID:39068414
Cyclophilin C as a Novel Diagnostic and Prognostic Biomarker of Coronary Artery Diseases. A Systematic Review and Meta-Analysis., PMID:37209796
Association of cyclophilins and cardiovascular risk factors in coronary artery disease., PMID:36935755
Chaperoning activity of the cyclophilin family prevents tau aggregation., PMID:36305768
Extracellular cyclophilins A and C induce dysfunction of pancreatic microendothelial cells., PMID:36277217
Association of a Combined Cancer Exhaustion Score with Circulating Tumor Cells and Outcome in Ovarian Cancer-A Study of the OVCAD Consortium., PMID:34884980
Roles of virulence regulator ToxR in viable but non-culturable formation by controlling reactive oxygen species resistance in pathogen Vibrio alginolyticus., PMID:34700184
[Increase of serum cyclophilin C levels in the follow-up of coronary artery disease: A biomarker and possible clinical predictor]., PMID:34594052
Ppic modulates CCl4-induced liver fibrosis and TGF-β-caused mouse hepatic stellate cell activation and regulated by miR-137-3p., PMID:34224798
Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice., PMID:33864384
Interfacial dilatational and emulsifying properties of ultrasound-treated pea protein., PMID:33618095
Salmonella Typhimurium peptidyl-prolyl cis-trans isomerase C (PPIase C) plays a substantial role in protein folding to maintain the protein structure., PMID:33029674
Identification of Substrates of Cytoplasmic Peptidyl-Prolyl Cis/Trans Isomerases and Their Collective Essentiality in Escherichia Coli., PMID:32545723
High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease., PMID:31332225
Comparative evaluation of structure and characteristic of peptidyl-prolyl cis-trans isomerase proteins and their function in Salmonella Typhimurium stress responses and virulence., PMID:31111418
α-Ketoglutarate drives electroneutral NaCl reabsorption in intercalated cells by activating a G-protein coupled receptor, Oxgr1., PMID:28771454
PPIC, EMP3 and CHI3L1 Are Novel Prognostic Markers for High Grade Glioma., PMID:27801851
Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules., PMID:26691022
The efficacy of the administration of recombinant human soluble thrombomodulin in patients with DIC., PMID:26590919
Identifying specific proteins involved in eggshell membrane formation using gene expression analysis and bioinformatics., PMID:26470705
Integrated compensatory network is activated in the absence of NCC phosphorylation., PMID:25893600
Identification of peptidoglycan-associated proteins as vaccine candidates for enterococcal infections., PMID:25369230
Depletion of cyclophilins B and C leads to dysregulation of endoplasmic reticulum redox homeostasis., PMID:24990953
Cotreatment with interleukin 4 and interleukin 10 modulates immune cells and prevents hypertension in pregnant mice., PMID:24906486
Identification of genes expressed during Toxoplasma gondii infection by in vivo-induced antigen technology (IVIAT) with positive porcine sera., PMID:24646180
90K, an interferon-stimulated gene product, reduces the infectivity of HIV-1., PMID:24156545
TLR3-induced placental miR-210 down-regulates the STAT6/interleukin-4 pathway., PMID:23844087
Low-scale expression and purification of an active putative iduronate 2-sulfate sulfatase-Like enzyme from Escherichia coli K12., PMID:23625223
MiR-29c is downregulated in gastric carcinomas and regulates cell proliferation by targeting RCC2., PMID:23442884
Deletion of pic results in decreased virulence for a clinical isolate of Shigella flexneri 2a from China., PMID:23391153
Molecular characterization of circulating tumor cells in patients with ovarian cancer improves their prognostic significance -- a study of the OVCAD consortium., PMID:23017820
Control of apple blue mold by Pichia pastoris recombinant strains expressing cecropin A., PMID:22108897
Cyclophilin C-associated protein regulation of phagocytic functions via NFAT activation in macrophages., PMID:21435337
Endogenous plasma activated protein C levels and the effect of enoxaparin and drotrecogin alfa (activated) on markers of coagulation activation and fibrinolysis in pulmonary embolism., PMID:21241489
Coupling aerobic biodegradation of methanol vapors with heterologous protein expression of endochitinase Ech42 from Trichoderma atroviride in Pichia pastoris., PMID:20709543
Cyclophilin C-associated protein/Mac-2 binding protein colocalizes with calnexin and regulates the expression of tissue transglutaminase., PMID:20049854
Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane., PMID:19627619
Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients., PMID:17576924
Thrombin-cleaved COOH(-) terminal osteopontin peptide binds with cyclophilin C to CD147 in murine breast cancer cells., PMID:17483319
Cyclophilin C-associated protein is up-regulated during wound healing., PMID:16998803
Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray., PMID:16367923
Elevated plasma levels of fibrin degradation products by granulocyte-derived elastase in patients with disseminated intravascular coagulation., PMID:16244764
Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins., PMID:16143140
Import of rat mitochondrial citrate carrier (CIC) at increasing salt concentrations promotes presequence binding to import receptor Tom20 and inhibits membrane translocation., PMID:16129883
[Expression of a human single-chain Fv antibody against HBsAg in Pichia pastoris]., PMID:15969030
Cyclophilin C-associated protein and cyclophilin C mRNA are upregulated in penumbral neurons and microglia after focal cerebral ischemia., PMID:15647740