Catalog No.
YHE44501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg201-Ala442
Predicted molecular weight
28.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43694
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GATA4, GATA-binding factor 4, Transcription factor GATA-4
Brain-Specific Gata4 Downregulation in Greywick Female Mice Models the Metabolic Subtype of Polycystic Ovary Syndrome., PMID:40515561
RNA m6A dynamics promote transcription and RNA stability of bivalent genes during iPSC-induced generation of human lung progenitors., PMID:40483690
Inhibition of the NLR pathway alleviates MAPK1 mutation-driven proliferation and differentiation deficits and enhanced apoptosis in P19 cells., PMID:40466562
Upstream open reading frame inactivation augments GATA4 translation and cardiomyocyte hypertrophy in mice., PMID:40463063
Kisspeptin-54 Restores Blood-Brain Barrier Integrity via GATA-4 in Ischemic Stroke., PMID:40454669
ITGB3 and associated molecules as critical biomarkers in Cesarean Scar Pregnancy., PMID:40442657
Innovative unsaturated polyurethane for cardiac regeneration: Enhancing cytocompatibility and gene expression through gelatin modification., PMID:40441578
Characterization of a Novel GATA4 Missense Variant p.Gly303Trp in a Family with Septal Heart Defects and Pulmonary Stenosis., PMID:40430071
Identification and Functional Characterization of a Novel SOX4 Mutation Predisposing to Coffin-Siris Syndromic Congenital Heart Disease., PMID:40426787
[GATA4/MYOM2 axis mediates the protective effect of folic acid on sodium arsenite-exposed cardiomyocytes and mouse embryonic heart development]., PMID:40355336
Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development., PMID:40349219
The effects of green light-emitting diode irradiation and inducer factors on the differentiation of human adipose tissue-derived mesenchymal cells into myocardial-like cells., PMID:40347405
Computational simulations aided prioritization of genomic targets for congenital heart disease (CHD) against developmental toxicity., PMID:40334872
Genetic variants and molecular profiling of 46,XY gonadal dysgenesis using whole-exome sequencing., PMID:40290305
Maturation of human induced pluripotent stem cell-derived cardiomyocytes promoted by Brachyury priming., PMID:40275010
Unveiling the role of GATA4 in endothelial cell senescence and atherosclerosis development., PMID:40209341
Aging-associated Increase of GATA4 levels in Articular Cartilage is Linked to Impaired Regenerative Capacity of Chondrocytes and Osteoarthritis., PMID:40166328
Breast cancer gene-1 (BRCA1) potentiates maladaptive repair after kidney injury., PMID:40152784
MAP Kinase Phosphatase-5 Deficiency Improves Endurance Exercise Capacity., PMID:40136658
The sotos syndrome gene Nsd1 safeguards developmental gene enhancers poised for transcription by maintaining the precise deposition of histone methylation., PMID:40118455
FOXL2 drives the differentiation of supporting gonadal cells in early ovarian development., PMID:40102860
D-tetramethrin induces cardiac looping failure in zebrafish during embryonic development., PMID:40086682
Using genetics, genomics, and transcriptomics to identify therapeutic targets in juvenile idiopathic arthritis., PMID:40083163
Blockade of ZMIZ1-GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage., PMID:40040621
Esketamine induces embryonic and cardiac malformation through regulating the nkx2.5 and gata4 in zebrafish., PMID:40021926
Cell enlargement modulated by GATA4 and YAP instructs the senescence-associated secretory phenotype., PMID:39962062
Cardiomyocyte SORBS2 expression increases in heart failure and regulates integrin interactions and extracellular matrix composition., PMID:39957251
Cardiovascular disease-associated non-coding variants disrupt GATA4-DNA binding and regulatory functions., PMID:39943688
Importance of N2BA Titin in Maintaining Cardiac Homeostasis and Its Role in Dilated Cardiomyopathy., PMID:39932400
Knockdown ATG5 gene by rAAV9 alleviates doxorubicin-induced cardiac toxicity by inhibiting GATA4 autophagic degradation., PMID:39931517
Regulation of senescence-associated secretory phenotypes in osteoarthritis by cytosolic UDP-GlcNAc retention and O-GlcNAcylation., PMID:39904978
Semiquantitative Cardiac-Specific Gene Expression Validation of the DNA Methylation Microarray in Human Mesenchymal Stem Cells., PMID:39900757
c-JUN: a chromatin repressor that limits mesoderm differentiation in human pluripotent stem cells., PMID:39876710
Doxorubicin-induced phosphorylation of lamin A/C enhances DNMT1 and activates cardiomyocyte death via suppressing GATA-4 and Bcl-xL in rat heart., PMID:39864225
Heart Morphogenesis Requires Smyd1b for Proper Incorporation of the Second Heart Field in Zebrafish., PMID:39858599
Pharmacogenetic associations of GATA4 and KCNQ1 with ibrutinib cardiovascular toxicity., PMID:39832190
Targeting senescence and GATA4 in age-related cardiovascular disease: a comprehensive approach., PMID:39831933
Berberine Inhibited SASP-Related Inflammation through RXRα/PPARγ/NEDD4 Pathway in Atherosclerosis., PMID:39829230
GATA4 binding to the Sox9 enhancer mXYSRa/Enh13 is critical for testis differentiation in mouse., PMID:39827212
Enhanced sensitivity and scalability with a Chip-Tip workflow enables deep single-cell proteomics., PMID:39820750
An autocrine synergistic desmin-SPARC network promotes cardiomyogenesis in cardiac stem cells., PMID:39734020
Single-cell analysis of bidirectional reprogramming between early embryonic states identify mechanisms of differential lineage plasticities in mice., PMID:39729987
Enhancing cardiac regeneration: direct reprogramming of fibroblasts into myocardial-like cells using extracellular vesicles secreted by cardiomyocytes., PMID:39718680
Brachyury co-operates with polycomb protein RYBP to regulate gastrulation and axial elongation in vitro., PMID:39676794
Cardiac Reprogramming and Gata4 Overexpression Reduce Fibrosis and Improve Diastolic Dysfunction in Heart Failure With Preserved Ejection Fraction., PMID:39673349
The Core Circadian Clock Factor, Bmal1, Transduces Sex-specific Differences in Both Rhythmic and Nonrhythmic Gene Expression in the Mouse Heart., PMID:39658371
Ginsenoside Rg1 attenuates Aβ1-42-induced microglial cell apoptosis and inflammation in Alzheimer's disease via the GATA4/PDE4A/PI3K/AKT axis., PMID:39653247
KMT2A regulates the autophagy-GATA4 axis through METTL3-mediated m6A modification of ATG4a to promote NPCs senescence and IVDD progression., PMID:39572532
Intrinsic GATA4 expression sensitizes the aortic root to dilation in a Loeys-Dietz syndrome mouse model., PMID:39567770
Impact of hexafluoropropylene oxide trimer acid (HFPO-TA) on sex differentiation after exposures during different development stages of zebrafish (Danio rerio)., PMID:39536898
For research use only. Not for human or drug use.
