Catalog No.
YHE36101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe667-Asp865
Predicted molecular weight
25.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P42658
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DPP VI, Dipeptidyl aminopeptidase-related protein, Dipeptidyl peptidase 6, DPP6, Dipeptidyl aminopeptidase-like protein 6, Dipeptidyl peptidase IV-like protein, Dipeptidyl peptidase VI, DPPX
Activity-dependent degradation of Kv4.2 contributes to synaptic plasticity and behavior in Angelman syndrome model mice., PMID:40310720
The role of DPP6 dysregulation in neuropathology: from synaptic regulation to disease mechanisms., PMID:40109277
Histone H3 lysine 9 tri-methylation is associated with pterygium., PMID:40033254
Anti-dipeptidyl-peptidase-like protein-6 encephalitis with late-onset gastric cancer: A case report and 2-year follow-up., PMID:39960935
Genome-Wide Scans for Selection Signatures in Haimen Goats Reveal Candidate Genes Associated with Growth Traits., PMID:39857271
Clinical and Paraclinical Characterizations, Management, and Prognosis in DPPX Antibody-Associated Encephalitis: A Systematic Review., PMID:39693598
Ancillary subunits KChIP2c and DPP6 differentially modulate the inhibition of Kv4.2 channels by riluzole., PMID:39586396
The NIPBL-gene mutation of a Cornelia de Lange Syndrome patient causes deficits in the hepatocyte differentiation of induced Pluripotent Stem Cells via altered chromatin-accessibility., PMID:39453535
Vildagliptin showed anti-epileptic effects and promoted subthreshold A-type potassium currents by regulating DPPs and Kv4s binding., PMID:39245254
Case report: Ofatumumab treatment in anti-DPPX autoimmune encephalitis., PMID:39007139
GWAS Identifies DPP6 as Risk Gene of Cognitive Decline in Parkinson's Disease., PMID:38875006
Modulation of potassium channels by transmembrane auxiliary subunits via voltage-sensing domains., PMID:38503563
Association between DPP6 gene rs10260404 polymorphism and increased risk of sporadic amyotrophic lateral sclerosis (sALS): a meta-analysis., PMID:38381392
Polymorphism of ADAM12, DPP6 and PRKN genes and their associations with milk production traits in Holstein., PMID:37917556
Whole-Exome Sequencing Reveals the Genomic Profile and IL6ST Variants as a Prognostic Biomarker of Paraneoplastic Pemphigus-Associated Unicentric Castleman Disease., PMID:37839777
Gene-Environment Analyses Reveal Novel Genetic Candidates with Prenatal Tobacco Exposure in Relation to Risk for Childhood Acute Lymphoblastic Leukemia., PMID:37773025
Survey of organ-derived small extracellular vesicles and particles (sEVPs) to identify selective protein markers in mouse serum., PMID:37744304
[Effect of Zhenwu Decoction on electrical remodeling of cardiomyocytes in heart failure via I_(to)/Kv channels]., PMID:37474990
Papillary Thyroid Carcinoma: A thorough Bioinformatic Analysis of Gene Expression and Clinical Data., PMID:37372430
Aberrant methylation of dipeptidyl peptidase‑like 6 as a potential prognostic biomarker for lung adenocarcinoma., PMID:37123021
Systematic Review and Meta-Analyses of Aminopeptidases as Prognostic Biomarkers in Amyotrophic Lateral Sclerosis., PMID:37108335
Expression Profiles, Prognosis, and ceRNA Regulation of SRY-Related HMG-Box Genes in Stomach Adenocarcinoma., PMID:36749091
Construction of a prognostic model for lung squamous cell carcinoma based on immune-related genes., PMID:36455238
Proteomic Analysis of Pleural Effusions from COVID-19 Deceased Patients: Enhanced Inflammatory Markers., PMID:36428847
Alzheimer's disease/dementia-associated brain pathology in aging DPP6-KO mice., PMID:36209950
Neuronal Roles of the Multifunctional Protein Dipeptidyl Peptidase-like 6 (DPP6)., PMID:36012450
Modulation of KV4.3-KChIP2 Channels by IQM-266: Role of DPP6 and KCNE2., PMID:36012438
Activation and closed-state inactivation mechanisms of the human voltage-gated KV4 channel complexes., PMID:35597238
Prognostic significance of AP-2α/γ targets as cancer therapeutics., PMID:35361846
An integrated analysis of the effects of maternal broccoli sprouts exposure on transcriptome and methylome in prevention of offspring mammary cancer., PMID:35263365
Genomewide Association Analyses of Lactation Persistency and Milk Production Traits in Holstein Cattle Based on Imputed Whole-Genome Sequence Data., PMID:34828436
Copy number variations in a Brazilian cohort with autism spectrum disorders highlight the contribution of cell adhesion genes., PMID:34664255
The Mediation Effects of Aluminum in Plasma and Dipeptidyl Peptidase Like Protein 6 (DPP6) Polymorphism on Renal Function via Genome-Wide Typing Association., PMID:34639784
Structural basis of gating modulation of Kv4 channel complexes., PMID:34552243
KCND2 variants associated with global developmental delay differentially impair Kv4.2 channel gating., PMID:34245260
Reply: Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population., PMID:33591373
Lack of evidence supporting a role for DPP6 sequence variants in Alzheimer's disease in the European American population., PMID:33591372
Development of a 12-biomarkers-based prognostic model for pancreatic cancer using multi-omics integrated analysis., PMID:33253517
A novel structure associated with aging is augmented in the DPP6-KO mouse brain., PMID:33225987
Neuronal Differentiation of Induced Pluripotent Stem Cells from Schizophrenia Patients in Two-Dimensional and in Three-Dimensional Cultures Reveals Increased Expression of the Kv4.2 Subunit DPP6 That Contributes to Decreased Neuronal Activity., PMID:33143549
Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing., PMID:33019671
Prognostic factor identification by analysis of the gene expression and DNA methylation data in glioma., PMID:32987560
Co-occurrence of antibodies against dipeptidyl-peptidase-like protein-6 and aquaporin-4 during a case of paraneoplastic encephalitis., PMID:32702576
Dipeptidyl peptidase like 6 promoter methylation is a potential prognostic biomarker for pancreatic ductal adenocarcinoma., PMID:32701143
Identification and validation of novel DNA methylation markers for early diagnosis of lung adenocarcinoma., PMID:32688456
A Knock-Down Cell-Based Study for the Functional Analysis of Chloride Intracellular Channel 1 (CLIC1): Integrated Proteomics and Microarray Study., PMID:32586242
Transcriptome analysis of neural progenitor cells derived from Lowe syndrome induced pluripotent stem cells: identification of candidate genes for the neurodevelopmental and eye manifestations., PMID:32393163
Activity-dependent isomerization of Kv4.2 by Pin1 regulates cognitive flexibility., PMID:32218435
Auxiliary subunits control biophysical properties and response to compound NS5806 of the Kv4 potassium channel complex., PMID:31914636
A nanobody-based nuclear imaging tracer targeting dipeptidyl peptidase 6 to determine the mass of human beta cell grafts in mice., PMID:31873789
For research use only. Not for human or drug use.
