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Recombinant Human CD86/B7-2 Protein, N-His

Catalog #:   YHE33801 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: P42081
Protein length: Leu26-Ala134
Overview

Catalog No.

YHE33801

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Leu26-Ala134

Predicted molecular weight

15.01 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P42081

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human CD86/B7-2 protein
References

Mechanistic investigation of calcium phosphate mineralization potentiating the cellular immune response of foot-and-mouth disease virus-like particle vaccines., PMID:40512119

The landscape and clinical impact of tumor-associated macrophages and PD-L1 in primary breast cancers and their brain metastases., PMID:40510346

Cyclic GMP-AMP Synthase (cGAS) Deletion Promotes Less Prominent Inflammatory Macrophages and Sepsis Severity in Catheter-Induced Infection and LPS Injection Models., PMID:40507879

Immunogen display on virus-like particles assembled from redesigned transcription activator-like effector proteins and nucleic acids: Activation of antigen-presenting cells., PMID:40499864

Activated CD4+ T cells upregulate PD-L1 expression on B cells through CD40/CD40L signaling and direct contact in systemic lupus erythematosus., PMID:40499670

Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation., PMID:40496861

Fungal immunization potentiates CD4+ T cell-independent cDC2 responses for cross-presentation., PMID:40491915

CTLA-4 blockade in ovarian cancer immunotherapy: Mechanisms and clinical strategies., PMID:40482550

NEK2 regulates B cell function and the severity of experimental autoimmune encephalomyelitis., PMID:40481479

Levistilide A Attenuates Carbon Tetrachloride (CCl4)-Induced Liver Fibrosis by Inhibiting the NF-κB/iNOS/NO Signalling Pathway in M1 Macrophages., PMID:40480397

Methyltransferase 3-mediated m6A modification of Switch/sucrose non-fermenting-related matrix-associated actin-dependent regulator of chromatin subfamily a member 5 promotes mycobacterium tuberculosis-infected macrophage M1 polarization and inflammation., PMID:40469707

[Mechanism of vanillic acid against cardiac fibrosis induced by isoproterenol in mice based on Drp1/HK1/NLRP3 and mitochondrial apoptosis signaling pathways]., PMID:40461229

The novel role of Yin Yang 1 in acute rejection of liver allografts through activation of dendritic cells., PMID:40458393

In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers., PMID:40453410

miRNA let-7-5p present in the extracellular vesicles of Trichinella spiralis newborn larvae inhibits the function of M1-type RAW264.7 macrophages by targeting C/EBPδ., PMID:40452071

Prostaglandin E2 receptor EP4 activation induces tolerogenic dendritic cells to mitigate ischemic acute kidney injury., PMID:40450025

Hyperbaric oxygen therapy attenuates carbon monoxide-induced lung injury by restoring mitochondrial dynamics and suppressing Pink1/Parkin-mediated mitophagy., PMID:40441279

Modulating the renin-angiotensin system by eprosartan or xanthenone drives microglial M2 polarization in a rat model of Parkinson's disease via regulating the interplay between MKP-1/ miR-155 /SOCS1 and PP2A signaling network., PMID:40440958

Interleukin-37 modulates microglial phenotype and inhibits inflammatory response via the MyD88/NF-κB pathway in lipopolysaccharide-induced neuroinflammation., PMID:40439750

Codonopsis pilosula Polysaccharides Exert Antiviral Effect Through Activating Immune Function in a Macrophage Model of Bovine Viral Diarrhea Virus Infection., PMID:40431508

Ginsenoside Rh2 Mitigates Endoplasmic Reticulum Stress-Induced Apoptosis and Inflammation and Through Inhibition of Hepatocyte-Macrophage Inflammatory Crosstalk., PMID:40431422

Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth., PMID:40430260

Low Fluoride Regulates Macrophage Polarization Through Mitochondrial Autophagy Mediated by PINK1/Parkin Axis., PMID:40427540

[Dynamics of eosinophil infiltration and microglia activation in brain tissues of mice infected with Angiostrongylus cantonensis]., PMID:40425499

[Effects of Toxoplasma gondii type I/II rhoptry protein 16 on the polarization and inflammatory response of mouse alveolar macrophages]., PMID:40425495

Effective cellular and neutralizing immunity against SARS-CoV-2 after mRNA booster vaccination is associated with pDC and B cell activation., PMID:40421016

Circ_0008285 regulates macrophage polarization through miR-375/MAPK14 axis in sepsis-induced acute lung injury., PMID:40418306

Human Amniotic Fluid-Derived Exosomes Alleviate Neuropathic Pain by Inducing an Anti-Inflammatory Transition in Microglia., PMID:40417920

Secretor and non-secretor human milk oligosaccharides differentially modulate immune response in the presence of cow's milk allergen β-lactoglobulin in an in vitro sensitization model., PMID:40416953

Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization., PMID:40415369

Lycium barbarum glycopeptide alleviates retinal inflammation by suppressing microglial M1 polarization via NF-κB/MAPK pathways., PMID:40412789

miR-29a nanoparticles improve chronic insomnia by regulating microglia activation and hippocampal neuronal cell pyroptosis through PER2/NF-κB axis., PMID:40412133

TFE3-mediated lysosomal biogenesis and homeostasis alleviates arsenic-induced lysosomal and immune dysfunction in macrophages., PMID:40409189

Malvidin Alleviates Lipopolysaccharide-Induced Acute Lung Injury by Modulating JAK2/STAT3 Signaling to Inhibit Macrophage M1 Polarization and Oxidative Stress., PMID:40397040

The evaluation of a novel multi-epitope vaccine against human papillomavirus and Candida albicans., PMID:40390500

Hub genes and key pathways of Graves' disease: bioinformatics analysis and validation., PMID:40388080

Cold-Induced RNA-Binding Protein (CIRP) Affects Cerebral Ischemia-Reperfusion Injury Through NF-κB Pathway., PMID:40381168

Genetically engineered K562 cells augment NK cell cytotoxicity against acute myeloid leukemia and reduce dependency on IL-15., PMID:40372524

Deer Antler Uridine Regulates Glycolysis in Microglia via HSP90/HIF-1α to Improve Cognitive Impairment in Alzheimer's Disease Mice., PMID:40365745

pH-responsive nano-vaccine combined with anti-PD-1 antibodies for enhanced immunotherapy of breast cancer., PMID:40365283

Blocking plasma cell fate enhances antigen-specific presentation by B cells to boost anti-tumor immunity., PMID:40360528

Oleanolic Acid Alleviates Neuronal Ferroptosis in Subarachnoid Hemorrhage by Inhibiting KEAP1-Nrf2 and NF-κB Pathways., PMID:40358968

The immunostimulatory activity of Epimedium flavonoids involves toll-like receptor 7/8., PMID:40351409

[Experimental study on Jianpi Qutan Formula regulating M1/M2 macrophage polarization to improve atherosclerosis]., PMID:40350948

Novel oncolytic vaccinia virus armed with interleukin-27 is a potential therapeutic agent for the treatment of murine pancreatic cancer., PMID:40350204

The overexpression of miR-146a in hippocampal microglia via IRAK1/TRAF6/NF-κB pathway improves cognitive function in diabetic mice., PMID:40349816

Evidence for Imbalanced Polarization of Caruncle Macrophages in Retained Placenta of Dairy Cows., PMID:40349759

Treg Control of CD80/CD86 Expression Mediates Immune System Homeostasis., PMID:40346769

Contezolid, a novel oxazolidinone antibiotic, acts as a potential anti-inflammatory agent., PMID:40341835

Immunomodulatory effects of dental pulp stem cells on lymphocytes and monocytes from patients with rheumatoid arthritis., PMID:40338061

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Human CD86/B7-2 Protein, N-His [YHE33801]
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