Catalog No.
YHE30001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu171
Predicted molecular weight
21.89 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P41208
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CEN2, Caltractin isoform 1, CALT, CETN2, Centrin-2
Role of the nucleotide excision repair function of CETN2 in the inhibition of the sensitivity of hepatocellular carcinoma cells to oxaliplatin., PMID:39945187
Astrocytic centrin-2 expression in entorhinal cortex correlates with Alzheimer's disease severity., PMID:39145525
Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7., PMID:39056782
Age-dependent functional development pattern in neonatal brain: An fMRI-based brain entropy study., PMID:38852805
The Chlamydia trachomatis type III-secreted effector protein CteG induces centrosome amplification through interactions with centrin-2., PMID:37155906
High expression of CETN2 is associated with platinum resistance and poor prognosis in epithelial ovarian cancer., PMID:36527574
Proteins associated with future suicide attempts in bipolar disorder: A large-scale biomarker discovery study., PMID:35697758
Centrin 2: A Novel Marker of Mature and Neoplastic Human Astrocytes., PMID:35573835
Protein Dimerization via Tyr Residues: Highlight of a Slow Process with Co-Existence of Numerous Intermediates and Final Products., PMID:35163094
Every protagonist has a sidekick: Structural aspects of human xeroderma pigmentosum-binding proteins in nucleotide excision repair., PMID:34420242
Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair., PMID:34099686
Identification of potential biomarkers and candidate small molecule drugs in glioblastoma., PMID:32874133
Diverged morphology changes of astrocytic and neuronal primary cilia under reactive insults., PMID:32122360
Genetic diversity and functional effect of common polymorphisms in genes involved in the first heterodimeric complex of the Nucleotide Excision Repair pathway., PMID:31865061
DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcription., PMID:31527837
Differential requirements for the EF-hand domains of human centrin 2 in primary ciliogenesis and nucleotide excision repair., PMID:31492759
Evaluation of novel highly specific antibodies to cancer testis antigen Centrin-1 for radioimmunoimaging and radioimmunotherapy of pancreatic cancer., PMID:31309741
Identification of Potential Biomarkers with Diagnostic Value in Pituitary Adenomas Using Prediction Analysis for Microarrays Method., PMID:31280474
Calcium and phosphorylation double-regulating caltractin initiating target protein XPC function., PMID:31202846
14-3-3 proteins mediate the localization of Centrin2 to centrosome., PMID:31180055
Deletion of both centrin 2 (CETN2) and CETN3 destabilizes the distal connecting cilium of mouse photoreceptors., PMID:30647131
Separation and Loss of Centrioles From Primordidal Germ Cells To Mature Oocytes In The Mouse., PMID:30143724
Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers., PMID:29793947
Chromosomal instability in women with primary ovarian insufficiency., PMID:29425284
FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration., PMID:29348145
Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton., PMID:27573463
Ciliopathy-associated IQCB1/NPHP5 protein is required for mouse photoreceptor outer segment formation., PMID:27328943
A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin., PMID:26923803
Centrosomes in the DNA damage response--the hub outside the centre., PMID:26614090
Centrin 3 is an inhibitor of centrosomal Mps1 and antagonizes centrin 2 function., PMID:26354417
Binding Pattern Elucidation of NNK and NNAL Cigarette Smoke Carcinogens with NER Pathway Enzymes: an Onco- Informatics Study., PMID:26225671
Microarray Analysis of the Major Depressive Disorder mRNA Profile Data., PMID:26207134
Centrin-2 (Cetn2) mediated regulation of FGF/FGFR gene expression in Xenopus., PMID:26014913
Functional and mechanistic studies of XPC DNA-repair complex as transcriptional coactivator in embryonic stem cells., PMID:25901318
Centrin2 regulates CP110 removal in primary cilium formation., PMID:25753040
How protein structure affects redox reactivity: example of Human centrin 2., PMID:25308418
Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity., PMID:24790208
The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells., PMID:24607542
PIPKIγ targets to the centrosome and restrains centriole duplication., PMID:24434581
Human TREX2 components PCID2 and centrin 2, but not ENY2, have distinct functions in protein export and co-localize to the centrosome., PMID:24291146
CETN1 is a cancer testis antigen with expression in prostate and pancreatic cancers., PMID:24252580
Calcium-binding capacity of centrin2 is required for linear POC5 assembly but not for nucleotide excision repair., PMID:23844208
CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci., PMID:23840880
Computational analysis of protein-protein interfaces involving an alpha helix: insights for terphenyl-like molecules binding., PMID:23768251
Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair., PMID:23716636
A non-canonical mode of microtubule organization operates throughout pre-implantation development in mouse., PMID:23624836
Clinical implication of centrosome amplification and expression of centrosomal functional genes in multiple myeloma., PMID:23522059
High LET radiation amplifies centrosome overduplication through a pathway of γ-tubulin monoubiquitination., PMID:23433796
Relative stability of human centrins and its relationship to calcium binding., PMID:23346931
Probing structural and motional features of the C-terminal part of the Human Centrin 2/P17-XPC microcrystalline complex by solid-state NMR spectroscopy., PMID:23190348
For research use only. Not for human or drug use.
