Catalog No.
YHE28101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Ala334
Predicted molecular weight
63.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P40925
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MDHA, Malate dehydrogenase, cytoplasmic, Cytosolic malate dehydrogenase, MDH1, Diiodophenylpyruvate reductase
Hydroxysafflor yellow A ameliorates myocardial ischemia/reperfusion injury by promoting MDH1-mediated mitochondrial metabolic homeostasis., PMID:40513321
Identification and validation of pyroptosis-related genes in Alzheimer's disease based on multi-transcriptome and machine learning., PMID:40438507
IDH1/MDH1 deacetylation activates the cGAS-STING pathway by promoting NETosis in acute liver failure., PMID:40388861
TNFRSF11B-modified umbilical cord mesenchymal stem cells as a novel strategy for bone-related diseases by suppressing osteoclast activity., PMID:40380204
Cerebrospinal fluid proteome profiling across the Alzheimer's disease continuum: a step towards solving the equation for 'X'., PMID:40329321
M2 macrophages-derived exosomal MDH1 drives lung adenocarcinoma progression via the Hippo/YAP signaling., PMID:40090126
Mutagenesis of AcSQBP9 in kiwifruit results in reduction of malate via alteration of the expression of a plastidial malate dehydrogenase., PMID:40052512
Role of malate dehydrogenase 1 and isocitrate dehydrogenase 1 and their posttranslational modifications in diseases., PMID:40022816
Nicotinamide dual treatment enhances morula-to-blastocyst transition through binding to Zonula Occludens-1 protein., PMID:39987859
Analysis and exploration of regulatory mechanisms and potential prognostic biomarkers in squamous cell carcinoma of the lung by expression profiling., PMID:39974402
Exploring novel drug targets for erectile dysfunction through plasma proteome with genome., PMID:39790564
A pilot study of transcriptomic preimplantation genetic testing (PGT-T): towards a new step in embryo selection?, PMID:39719045
A linker histone acts as a transcription factor to orchestrate malic acid accumulation in apple in response to sorbitol., PMID:39705498
Model-assisted CRISPRi/a library screening reveals central carbon metabolic targets for enhanced recombinant protein production in yeast., PMID:39615667
Asparagine Availability Is a Critical Limiting Factor for Infectious Spleen and Kidney Necrosis Virus Replication., PMID:39459874
Transcriptomic and metabolomic analyses reveal the positive effect of moderate concentration of sodium chloride treatment on the production of β-carotene, torulene, and torularhodin in oleaginous red yeast Rhodosporidiobolus odoratus XQR., PMID:39399738
Visnagin alleviates rheumatoid arthritis via its potential inhibitory impact on malate dehydrogenase enzyme: in silico, in vitro, and in vivo studies., PMID:39390383
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease., PMID:39385222
IDH1/MDH1 deacetylation promotes NETosis by regulating OPA1 and autophagy., PMID:39353390
High-dimensional proteomic analysis for pathophysiological classification of traumatic brain injury., PMID:39323289
Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms., PMID:39117624
Associations between genetically predicted concentrations of plasma proteins and the risk of prostate cancer., PMID:39068416
Physiology of malate dehydrogenase and how dysregulation leads to disease., PMID:38962852
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease., PMID:38947065
Identification of Candidate Protein Biomarkers Associated with Domoic Acid Toxicosis in Cerebrospinal Fluid of California Sea Lions (Zalophus californianus)., PMID:38807289
Proteomics of tumor and serum samples from isocitrate dehydrogenase-wildtype glioblastoma patients: is the detoxification of reactive oxygen species associated with shorter survival?, PMID:38803161
An insertion in the promoter of a malate dehydrogenase gene regulates malic acid content in apple fruit., PMID:38788771
Targeting c-Myc transactivation by LMNA inhibits tRNA processing essential for malate-aspartate shuttle and tumour progression., PMID:38769668
SpCTP3 from the hyperaccumulator Sedum plumbizincicola positively regulates cadmium tolerance by interacting with SpMDH1., PMID:38739960
Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia., PMID:38485816
A novel HDAC6 inhibitor attenuate APAP-induced liver injury by regulating MDH1-mediated oxidative stress., PMID:38484665
Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis., PMID:38347496
Alzheimer's Disease and Aging Association: Identification and Validation of Related Genes., PMID:38230733
IDH1/MDH1 deacetylation promotes acute liver failure by regulating NETosis., PMID:38172700
Developmental and epileptic encephalopathy 82 (DEE82) with novel compound heterozygous mutations of GOT2 gene., PMID:37977948
A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls., PMID:37775827
Chemical Hypoxic Preconditioning Improves Survival and Proliferation of Mesenchymal Stem Cells., PMID:37755639
Metabolomic response to high light from pgrl1 and pgr5 mutants of Chlamydomonas reinhardtii., PMID:37751074
Legume-specific SnRK1 promotes malate supply to bacteroids for symbiotic nitrogen fixation., PMID:37598296
HPV18 E6 inhibits α-ketoglutarate-induced pyroptosis of esophageal squamous cell carcinoma cells via the P53/MDH1/ROS/GSDMC pathway., PMID:37402485
A MICROGLIAL ACTIVITY STATE BIOMARKER PANEL DIFFERENTIATES FTD-GRANULIN AND ALZHEIMER'S DISEASE PATIENTS FROM CONTROLS., PMID:37398209
Human peroxisomal NAD+/NADH homeostasis is regulated by two independent NAD(H) shuttle systems., PMID:37355054
The self-association of cytoplasmic malate dehydrogenase 1 promotes malate biosynthesis and confers disease resistance in cassava., PMID:37321041
The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis., PMID:37221841
Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase., PMID:37036365
Tat-malate dehydrogenase fusion protein protects neurons from oxidative and ischemic damage by reduction of reactive oxygen species and modulation of glutathione redox system., PMID:37024665
Multienzyme activity profiling for evaluation of cell-to-cell variability of metabolic state., PMID:36349298
Proteomics study of mitochondrial proteins in tilapia red meat and their effect on color change during storage., PMID:36084591
Ketogenic Diet Treatment of Defects in the Mitochondrial Malate Aspartate Shuttle and Pyruvate Carrier., PMID:36079864
O-GlcNAcylation promotes pancreatic tumor growth by regulating malate dehydrogenase 1., PMID:35879546
For research use only. Not for human or drug use.
