Catalog No.
YHE24201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser43-Pro427
Predicted molecular weight
45.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P39656
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DDOST 48 kDa subunit, OST48, Oligosaccharyl transferase 48 kDa subunit, KIAA0115, DDOST, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit
Endocytosis, endoplasmic reticulum, actin cytoskeleton affected in tilapia liver under polystyrene microplastics and BDE153 acute co-exposure., PMID:39725183
N-glycosylation Modification of CTSD Affects Liver Metastases in Colorectal Cancer., PMID:39716927
Induction of oxidative- and endoplasmic-reticulum-stress dependent apoptosis in pancreatic cancer cell lines by DDOST knockdown., PMID:39223141
Inherited Retinal Degeneration Caused by Dehydrodolichyl Diphosphate Synthase Mutation-Effect of an ALG6 Modifier Variant., PMID:38256083
Functional classification of DDOST variants of uncertain clinical significance in congenital disorders of glycosylation., PMID:37848450
An immune-related multi-omics analysis of dolichyl-diphosphooligosaccharide protein glycosyltransferase in glioma: Prognostic value exploration and competitive endogenous RNA network identification., PMID:37606290
LncRNA TSIX aggravates spinal cord injury by regulating the PI3K/AKT pathway via the miR-532-3p/DDOST axis., PMID:37155292
A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery., PMID:36725334
Pathogenic DDOST Variant Is Associated with Humoral Immune Deficiency., PMID:36631682
Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis., PMID:36306698
DDOST-CDG: Clinical and molecular characterization of a third patient with a milder and a predominantly movement disorder phenotype., PMID:36214423
DDOST Correlated with Malignancies and Immune Microenvironment in Gliomas., PMID:35812432
Upregulation of ribosome complexes at the blood-brain barrier in Alzheimer's disease patients., PMID:35766008
Advanced Glycation End Products: A Sweet Flavor That Embitters Cardiovascular Disease., PMID:35269546
Prognostic Biomarker DDOST and Its Correlation With Immune Infiltrates in Hepatocellular Carcinoma., PMID:35173766
Knockdown of Oligosaccharyltransferase Subunit Ribophorin 1 Induces Endoplasmic-Reticulum-Stress-Dependent Cell Apoptosis in Breast Cancer., PMID:34778038
The second DDOST-CDG patient with lactose intolerance, developmental delay, and situs inversus totalis., PMID:34462534
Identification of Potentially Related Genes and Mechanisms Involved in Skeletal Muscle Atrophy Induced by Excessive Exercise in Zebrafish., PMID:34439993
Anti-inflammatory and -apoptotic effects of a long-term herbal extract treatment on DSS-induced colitis in mice fed with high AGEs-fat diet., PMID:34380504
Systemic Bioinformatic Analyses of Nuclear-Encoded Mitochondrial Genes in Hypertrophic Cardiomyopathy., PMID:34054926
Mitochondria Autoimmunity and MNRR1 in Breast Carcinogenesis: A Review., PMID:33615312
Expression of miRNA-203 and its target gene in hair follicle cycle development of Cashmere goat., PMID:33427027
Comprehensive Evaluation of Endocytosis-Associated Protein SCAMP3 in Hepatocellular Carcinoma., PMID:33116758
Proteomic Profiles of Thyroid Gland and Gene Expression of the Hypothalamic-Pituitary-Thyroid Axis Are Modulated by Exposure to AgNPs during Prepubertal Rat Stages., PMID:32972137
Identification of proteins associated with development of metastasis from cutaneous squamous cell carcinomas (cSCCs) via proteomic analysis of primary cSCCs., PMID:32794257
Advanced Glycated apoA-IV Loses Its Ability to Prevent the LPS-Induced Reduction in Cholesterol Efflux-Related Gene Expression in Macrophages., PMID:32410861
Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion., PMID:31541173
Synergistic alveolar bone resorption by diabetic advanced glycation end products and mechanical forces., PMID:31294467
Fructose-induced AGEs-RAGE signaling in skeletal muscle contributes to impairment of glucose homeostasis., PMID:31272030
Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function Screen., PMID:30650657
Identification of Core Genes and Key Pathways via Integrated Analysis of Gene Expression and DNA Methylation Profiles in Bladder Cancer., PMID:29739919
Dietary advanced glycated end-products and medicines influence the expression of SIRT1 and DDOST in peripheral mononuclear cells from long-term type 1 diabetes patients., PMID:29027826
N-acetylcysteine Counteracts Adipose Tissue Macrophage Infiltration and Insulin Resistance Elicited by Advanced Glycated Albumin in Healthy Rats., PMID:29018354
Increased liver AGEs induce hepatic injury mediated through an OST48 pathway., PMID:28947796
Candidate susceptibility variants for esophageal squamous cell carcinoma., PMID:28165652
N-Acetyl Cysteine Attenuated the Deleterious Effects of Advanced Glycation End-Products on the Kidney of Non-Diabetic Rats., PMID:27898405
[Study on gene differential expressions of substance and energy metabolism in chronic superficial gastritis patients of Pi deficiency syndrome and of pi-wei hygropyrexia syndrome]., PMID:23185754
Tandem affinity purification in transgenic mouse embryonic stem cells identifies DDOST as a novel PPP1CC2 interacting protein., PMID:23140390
DDOST mutations identified by whole-exome sequencing are implicated in congenital disorders of glycosylation., PMID:22305527
Expression of advanced glycation end-product receptors in the cochlea., PMID:20513044
DDOST, PRKCSH and LGALS3, which encode AGE-receptors 1, 2 and 3, respectively, are not associated with diabetic nephropathy in type 1 diabetes., PMID:20490454
A new complex homozygous large rearrangement of the PINK1 gene in a Sudanese family with early onset Parkinson's disease., PMID:19214605
Robust immunohistochemical staining of several classes of proteins in tissues subjected to autolysis., PMID:17312010
Genome organization of human 48-kDa oligosaccharyltransferase (DDOST)., PMID:9367678
For research use only. Not for human or drug use.
