Catalog No.
YHE12501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn783-Lys850
Predicted molecular weight
9.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35555
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FBN, Fibrillin-1, FBN1
Systematic review and meta-analysis of the effect of exercise training on asprosin in randomized controlled trials., PMID:40515432
Asprosin modulates female reproductive functions in teleosts: An in vitro study in Channa punctata., PMID:40513993
The Diversity of Fibrillin Functions: Lessons from the Periodontal Ligament., PMID:40497939
Dysregulation of cell migration by matrix metalloproteinases in geleophysic dysplasia., PMID:40481143
Relationship between plasma asprosin, dry matter intake, and plasma glucose at different stages of lactation., PMID:40470287
Identification of key genes regulating colorectal cancer stem cell characteristics by bioinformatics analysis., PMID:40441264
Exploring the Unique Extracellular Matrix Composition of Acomys as a Potential Key to Resisting Fibrosis., PMID:40407745
Vitreoretinal interface features in epiretinal membrane associated with pseudoexfoliation syndrome., PMID:40397163
The correlation between serum asprosin and type 2 diabetic patients with obesity in the community., PMID:40391011
Novel Aortic Dissection Model Links Endothelial Dysfunction and Immune Infiltration., PMID:40365676
Dihydroartemisinin Targets the NFIC/FBN1 Cascade to Enhance Wound Healing in Chronic Skin Ulcer by Inhibiting Fibroblast Ferroptosis., PMID:40358939
Sex- and age-dependent neurovascular abnormalities linked to neuroinflammation lead to exacerbated post-ischemic brain injury in Marfan syndrome mice., PMID:40349485
Case Report: A FBN1 frameshift-and-nonsense mutation and aortic dissection in Marfan syndrome., PMID:40336639
Is there a relationship between periodontal conditions and asprosin levels in gingival crevicular fluid, saliva and serum?, PMID:40301876
Asprosin and Neuregulin 4 in Obesity in Children., PMID:40283014
Mitochondrial Dysfunction: A New Hallmark in Hereditable Thoracic Aortic Aneurysm Development., PMID:40277943
Analysis of FBN1, TGFβ2, TGFβR1 and TGFβR2 mRNA as Key Molecular Mechanisms in the Damage of Aortic Aneurysm and Dissection in Marfan Syndrome., PMID:40243722
Endothelial Cell Senescence in Marfan Syndrome: Pathogenesis and Therapeutic Potential of TGF-β Pathway Inhibition., PMID:40240926
Asprosin-FABP5 Interaction Modulates Mitochondrial Fatty Acid Oxidation through PPARα Contributing to MASLD Development., PMID:40231957
Whole-exome sequencing screening for candidate genes and potential pathogenic variants associated with early-onset high myopia in 47 Chinese families., PMID:40175531
Reassessment of FBN1 variants of uncertain significance using updated ClinGen guidance for PP1/BS4 and PP4 criteria., PMID:40169830
Vitreous Fibrillar Structure and Interfibrillar Composition in Adult Mice., PMID:40162951
The relationship between the expression of serum asprosin and miR-21 in patients with osteoporosis and delayed healing after OVCF surgery., PMID:40153558
Low Serum Asprosin Levels in Fibromyalgia Syndrome: Insights from a Cross-Sectional Study., PMID:40142221
Epigenome editing-mediated restoration of FBN1 expression by demethylation of CpG island shore in porcine fibroblasts., PMID:40129967
Identification and functional validation of a novel FBN1 variant in a Marfan syndrome family using a zebrafish model., PMID:40128660
A novel missense variant of FBN1 gene in a Sardinian family with Marfan syndrome: a case report., PMID:40123664
Marfan syndrome variation of the POGLUT2 and POGLUT3 consensus sequence can produce aberrant fibrillin-1 O-glucosylation., PMID:40107616
Developing a more accurate population frequency of Marfan syndrome from predicted pathogenic FBN1 variants in the gnomAD cohorts., PMID:40102521
The diagnostic potential of Asprosin and Meteorin-like proteins in basal and squamous cell carcinomas., PMID:40095046
Novel De Novo BRCA2 Variant in an Early-Onset Ovarian Cancer Reveals a Unique Tumor Evolution Pathway., PMID:40076915
Marfan syndrome cardiomyocytes show excess of titin isoform N2BA and extended sarcomeric M-band., PMID:40062891
Corneal Biomechanics Are Associated With FBN1 Mutations in Patients With Marfan Syndrome and Ectopia Lentis., PMID:40062814
The Complicated Genetics behind Uncomplicated Type B Aortic Dissection., PMID:40058456
Unraveling a novel FBN1 variant in Marfan syndrome with dilated aortic root manifestation., PMID:40055687
Single Cell Proteomics Reveals Novel Cell Phenotypes in Marfan Mouse Aneurysm., PMID:40027651
Genetic landscape and ocular biometric correlations in microspherophakia: insights from a comprehensive patient cohort., PMID:40025527
Stabilisation of extracellular matrix is crucial to rapamycin-mediated life span increase in Marfan mgR/mgR mice., PMID:40021021
Prenatal Diagnosis of Congenital Paraesophageal Hernia With Gastric Volvulus and Postnatal FBN1 Mutation Confirmation., PMID:39993998
Predictive roles of Asprosin and Gremlin-1 expression in Egyptian pediatric patients with type 1 diabetes., PMID:39979315
Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model., PMID:39959812
Novel FBN1 intron variant causes isolated ectopia lentis via in-frame exon skipping., PMID:39939800
Prodomain processing controls BMP-10 bioactivity and targeting to fibrillin-1 in latent conformation., PMID:39921464
Changes in Gene Expression of the Extracellular Matrix in Patients with Full-Thickness Rotator Cuff Tears of Varying Sizes., PMID:39912080
Combined ADAMTS10 and ADAMTS17 inactivation exacerbates bone shortening and compromises extracellular matrix formation., PMID:39896540
Tauroursodeoxycholic acid inhibits endothelial-mesenchymal transition in high glucose-treated human umbilical vein endothelial cells., PMID:39893741
XOR-Derived ROS in Tie2-Lineage Cells Including Endothelial Cells Promotes Aortic Aneurysm Progression in Marfan Syndrome., PMID:39882602
mTOR/p70S6K signaling pathway promotes fibrillin-1 expression in AKI-to-CKD transition post CA/CPR., PMID:39880104
Total Anomalous Pulmonary Venous Return, Marfan Syndrome, and Severe Combined Immunodeficiency: A Lethal Combination?, PMID:39871773
Urinary Proteomic Shifts over Time and Their Associations with eGFR Decline in Chronic Kidney Disease., PMID:39858440
For research use only. Not for human or drug use.
