Catalog No.
YHE10001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser330-Val466
Predicted molecular weight
17.64 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35348
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADRA1C, ADRA1A, Alpha-1A adrenoreceptor, Alpha-1C adrenergic receptor, Alpha-adrenergic receptor 1c, Alpha-1A adrenoceptor, Alpha-1A adrenergic receptor
A gatekeeper sympathetic control of lacrimal tear secretion and dry eye onset through the NA-Adra1a-Ucp2 pathway., PMID:40473608
Mechanism of action of aloperine in the treatment of pulmonary arterial hypertension based on network pharmacology and molecular docking methods., PMID:40055190
Jiajian Shuyu pills effectively ameliorate cognitive impairment via regulating the inflammation of microglia in an Alzheimer's disease mouse model., PMID:39971019
Proteomic identification of potential biomarkers for heat tolerance in Caracu beef cattle using high and low thermotolerant groups., PMID:39538142
Leonurine Inhibits Hepatic Lipid Synthesis to Ameliorate NAFLD via the ADRA1a/AMPK/SCD1 Axis., PMID:39409181
Polypharmacological profiling across protein target families and cellular pathways using the multiplexed cell-based assay platform safetyProfiler reveals efficacy, potency and side effects of drugs., PMID:39405910
Acupuncture improves neuroendocrine defects in a preclinical rat model of reproductive aging., PMID:39366551
Proteomic changes of the bovine blood plasma in response to heat stress in a tropically adapted cattle breed., PMID:39149588
Sustained fentanyl exposure inhibits neuronal activity in dissociated striatal neuronal-glial cocultures through actions independent of opioid receptors., PMID:39110896
Structure-Based Drug Design of ADRA2A Antagonists Derived from Yohimbine., PMID:38857067
The alpha-1A adrenergic receptor regulates mitochondrial oxidative metabolism in the mouse heart., PMID:38331556
Network pharmacology combined with an animal model to reveal the material basis and mechanism of Amomum villosum in alleviating constipation in mice., PMID:38065427
Hsa_circ_0080608 Attenuates Lung Cancer Progression by Functioning as a Competitive Endogenous RNA to Regulate the miR-661/ADRA1A Pathway., PMID:37820700
Transcriptome analysis of osteogenic differentiation of human maxillary sinus mesenchymal stem cells using RNA-Seq., PMID:37800070
Prognostic Prediction Value and Biological Functions of Non-Apoptotic Regulated Cell Death Genes in Lung Adenocarcinoma., PMID:37622313
Idiopathic Pulmonary Fibrosis Molecular Substrates Revealed by Competing Endogenous RNA Regulatory Networks., PMID:37540140
Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease., PMID:37256468
Integrated LC-MS/MS and network pharmacology approach for predictingactive ingredients and pharmacological mechanisms of Tribulus terrestris L. against cardiac diseases., PMID:37042962
Tracing the pathways and mechanisms involved in the anti-breast cancer activity of glycyrrhizin using bioinformatics tools and computational methods., PMID:37042955
Increased angiotensin II coupled with decreased Adra1a expression enhances cardiac hypertrophy in pregnancy-associated hypertensive mice., PMID:36736425
Phenylephrine-Induced Contraction in Guinea Pig Thoracic Aorta Is Triggered by Stimulation of α1L-Adrenoceptors Functionally Coupled with Store-Operated Ca2+ Channels and Voltage-Dependent Ca2+ Channels., PMID:36724959
Venlafaxine increases aromatization, reduces apical V-ATPase in clear cells and induces increased number of mast cells and smooth muscle cells death in rat cauda epididymis., PMID:36584913
Differential gene expression during recall of behaviorally conditioned immune enhancement in rats: a pilot study., PMID:39834660
ADRA1A-Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP., PMID:36344764
The Mechanism of Crocetin Targeting Cardiovascular Disease Based on Network Pharmacology Constrained by Spectral Experiments., PMID:36251941
Vasovagal Syncope Is Associated with Variants in Genes Involved in Neurohumoral Signaling Pathways., PMID:36140820
Identification of novel proteins associated with movement-related adverse antipsychotic effects by integrating GWAS data and human brain proteomes., PMID:36030699
Vascular Reactions of the Diving Reflex in Men and Women Carrying Different ADRA1A Genotypes., PMID:36012699
Integrative analysis of the roles of lncRNAs and mRNAs in ischaemic preconditioning to alleviate liver ischaemia-reperfusion injury in mice., PMID:36007332
Hypermethylation in the promoter region of the ADRA1A gene is associated with opioid use disorder in Han Chinese., PMID:35964682
Adrenergic receptor signaling induced by Klf15, a regulator of regeneration enhancer, promotes kidney reconstruction., PMID:35939709
Cardiomyocyte-specific knockout of ADAM17 ameliorates left ventricular remodeling and function in diabetic cardiomyopathy of mice., PMID:35909160
A cardiac-null mutation of Prdm16 causes hypotension in mice with cardiac hypertrophy via increased nitric oxide synthase 1., PMID:35862303
Construction of Endometrial Carcinoma ceRNA Network and Screening of Key Genes Based on TCGA Database., PMID:35832124
Irisin Improves High-Fat Diet-Induced Sexual Dysfunction in Obese Male Rats., PMID:35189621
Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor., PMID:35063136
Weight-gain propensity and morphine withdrawal alters locomotor behavior and regional norepinephrine-related gene expression in male and female mice., PMID:35007656
Interplay between genetics and lifestyle on pain susceptibility in women with fibromyalgia: the al-Ándalus project., PMID:34875034
Irisin ameliorates male sexual dysfunction in paroxetine-treated male rats., PMID:34861466
Fibromyalgia: A Review of Related Polymorphisms and Clinical Relevance., PMID:34730627
MiR-3682 promotes the progression of hepatocellular carcinoma (HCC) via inactivating AMPK signaling by targeting ADRA1A., PMID:34706275
Venlafaxine-induced adrenergic signaling stimulates Leydig cells steroidogenesis via Nur77 overexpression: A possible role of EGF., PMID:34688693
Integrative Analyses of Genes Associated With Right Ventricular Cardiomyopathy Induced by Tricuspid Regurgitation., PMID:34603374
Effect of ingesting a meal and orthostasis on the regulation of splanchnic and systemic hemodynamics and the responsiveness of cardiovascular α1-adrenoceptors., PMID:34523347
Altered stress hormone levels affect in vivo vascular function in the hAPP23+/- overexpressing mouse model of Alzheimer's disease., PMID:34506227
Systematic Investigation of the Effect of Powerful Tianma Eucommia Capsule on Ischemic Stroke Using Network Pharmacology., PMID:34194527
Antidepressants Differentially Regulate Intracellular Signaling from α1-Adrenergic Receptor Subtypes In Vitro., PMID:34062902
Class A G protein-coupled receptors assemble into functional higher-order hetero-oligomers., PMID:34032285
The mechanisms of action of WeiChang'An Pill (WCAP) treat diarrhoea-predominant irritable bowel syndrome (IBS-D) using network pharmacology approach and in vivo studies., PMID:33862102
α1A-adrenaline receptors in dorsal horn inhibitory neurons have an inhibitory role in the regulation of chloroquine-induced itch in mice., PMID:33726812
For research use only. Not for human or drug use.
