Catalog No.
YHE08001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met533-Lys696
Predicted molecular weight
20.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35228
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nitric oxide synthase, inducible, NOS2A, Inducible NO synthase, HEP-NOS, Hepatocyte NOS, Peptidyl-cysteine S-nitrosylase NOS2, iNOS, NOS2, Inducible NOS, NOS type II
iNOS Mediates High-Fat Diet-Associated Aggravation of Complete Freund's Adjuvant-Induced Inflammatory Pain., PMID:40508229
Chronic administration of morphine provokes generation of antibodies to morphine and immunosuppression in individuals with opioid use disorder., PMID:40501089
Dynamic changes in vasohibin and nitric oxide signaling following surgical resection of head and neck squamous cell carcinoma., PMID:40483461
Deferential nephrotoxicity effect of lanthanum oxide nanoparticle responses to concentration and time in vivo., PMID:40481145
Exploring 5,7-dimethoxyflavone from Piper ornatum as a novel anti-breast cancer candidate: insights from in silico analysis., PMID:40465971
Identification of potential diagnostic markers and molecular mechanisms of asthma and ulcerative colitis based on bioinformatics and machine learning., PMID:40443529
Human microbiota influence the immune cell composition and gene expression in the tumor environment of a murine model of glioma., PMID:40443227
Discovery of Hydrazineyl Amide Derivative of Pseudolaric Acid B for Reprogramming Tumor-Associated Macrophages Against Tumor Growth., PMID:40430260
Astragalus Extract Mixture HT042 Reverses Cyclophosphamide-Induced Immunosuppression Through Dual Modulation of Innate and Adaptive Immunity., PMID:40429990
Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies., PMID:40425728
Protective Effects of Octyl Gallate Against Deoxynivalenol-Induced Colon Inflammation: Insights from Proteomic and Metabolomic Analyses., PMID:40400552
Deficiency of inducible nitric oxide synthase (iNOS) enhances MC903-induced atopic dermatitis-like inflammation in mice., PMID:40398095
Inducible nitric oxide synthase (iNOS): More than an inducible enzyme? Rethinking the classification of NOS isoforms., PMID:40389042
DNA Methylation of iNOS, eNOS, TP53 and LINE-1 in Gingival Tissues of Cigarette Smokers, Heat-Not-Burn Smokers and Never Smokers: An Exploratory Study., PMID:40387376
Astrocytic spermidine insufficiency contributes to enhanced pain sensitivity associated with ApoE4., PMID:40375206
The alterations of molecular repertoire of the RANKL-induced osteoclastogenesis in the M1 macrophage-derived inflammatory milieu., PMID:40341702
Gut microbiota dysbiosis orchestrates vitiligo-related oxidative stress through the metabolite hippuric acid., PMID:40329424
Integrated transcriptomic and metabolomic analyses reveal the mechanism by which quercetin inhibits reflux esophagitis in rats., PMID:40327723
[Effects of liver fibrosis induced by iron overload on M2 polarization of macrophages in mice]., PMID:40294917
cGAS/STING signalling in macrophages aggravates obliterative bronchiolitis via an IFN-α-dependent mechanism after orthotopic tracheal transplantation in mice., PMID:40292672
RETRACTION: Nanos2 Promotes Differentiation of Chicken (Gallus gallus) Embryonic Stem Cells to Male Germ Cells., PMID:40289626
Exploring the anti-inflammatory activity of fupenzic acid using network pharmacology and experimental validation., PMID:40274978
Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model., PMID:40272982
S100A8/A9 high-expression macrophages mediate renal tubular epithelial cell damage in acute kidney injury following acute type A aortic dissection surgery., PMID:40270593
Anti-inflammatory effects of Lactiplantibacillus plantarum strains through MAPK, NF-κB, and AP-1 signaling pathways and its application in soy milk., PMID:40263848
Macrophage heme oxygenase-1 modulates peroxynitrite-mediated vascular injury and exacerbates abdominal aortic aneurysm development., PMID:40261277
PTGS2 Silencing Inhibits Ferroptosis in Staphylococcus Aureus-induced Osteomyelitis By Blocking the IL-17A Signaling Pathway., PMID:40257651
The Impact of Recreational Diving to a Depth of 40 m on Selected Intracellular DAMPs., PMID:40243713
The prophylactic anti-aging effect of aspirin (acetylsalicylic acid) on oxidative stress-induced damage in the buccal mucosa of D-galactose-induced aged rats., PMID:40240423
CAR T cell-driven induction of iNOS in tumor-associated macrophages promotes CAR T cell resistance in B cell lymphoma., PMID:40235478
Microglial pro-inflammatory mechanisms induced by monomeric C-reactive protein are counteracted by soluble epoxide hydrolase inhibitors., PMID:40215773
Perfluorohexane Emulsions Induce Macrophage-Stimulating Effects through iNOS Expression., PMID:40215334
Pro-inflammatory effects of all-trans retinoic acid in experimental acute inflammation - insights into eosinophil and neutrophil dynamics., PMID:40207857
IL-27 accelerates diabetic wound healing by modulating macrophage polarization., PMID:40199138
Ferulic acid inhibits ox-LDL-induced ferroptosis and apoptosis in RAW 264.7 cells via the HIF-1 signaling pathway., PMID:40170728
Bioactive coumarins from Notopterygium incisum root: A step toward natural ant-infammatory candidates., PMID:40122302
GDF11 Regulates M1 and M2 Polarization of BV2 Microglial Cells via p38 MAPK Signaling Pathway., PMID:40100492
Neuroinflammation increases in old and oldest-old rats except for dura mater meningeal tissue with significant gender differences: a translational perspective., PMID:40085280
Therapeutic mitochondria treatment amplifies macrophage-mediated phagocytosis and recycling exocytosis., PMID:40079557
Probiotic, Paraprobiotic, and Postbiotic Activities of Lactiplantibacillus plantarum KUNN19-2 Against Non-Typhoidal Salmonella Serovars., PMID:40076451
Atrophic C2C12 Myotubes Activate Inflammatory Response of Macrophages In Vitro., PMID:40072046
L-Citrulline Alleviates Testicular Ischemia/Reperfusion Injury in Rats by Modulating eNOS/iNOS Induced Nitric Oxide Production, Inflammation, and Apoptosis., PMID:40059720
Protein disulfide isomerase integrates toll-like receptor 4 and P2X7 receptor signaling pathways during lipopolysaccharide-induced neuroinflammation., PMID:40050375
Toxicity enhancement of microplastics released from food containers through thermal aging: Absorbing more serum proteins thus activating the innate immune response via actin polymerization., PMID:40049044
LILRB4 specific overexpression in myeloid cells promotes tumor progression and immunosuppression in mouse models., PMID:40048761
Neuraminidase and nitric oxide dual response via PSA-PLGA nanoparticles: A novel approach for controlling Glaesserella parasuis inflammation and infection., PMID:40043976
P2X7 receptor augments kainic acid-induced nitrosative stress by abrogating GS-HSP25-mediated iNOS inhibition and GSH synthesis in the mouse hippocampus., PMID:40032027
Effects of Pesticide Exposure on Neuroinflammation and Microglial Gene Expression: Relevance to Mechanisms of Alzheimer's Disease Risk., PMID:40027678
The Protective Effects of Saxagliptin and Cilostazol in an Experimental Model of Cyclophosphamide-Induced Nephrotoxicity in Rats: Targeting iNOS/NF-kB and Nrf-2/HO-1 Pathways., PMID:40025827
Correlation between REDOX enzymes and NET markers expression during the development of periapical lesions in mice., PMID:40024980