Catalog No.
YHE07501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr2-Cys228
Predicted molecular weight
27.24 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35221
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Renal carcinoma antigen NY-REN-13, Catenin alpha-1, CTNNA1, Alpha E-catenin, Cadherin-associated protein
Paclitaxel/Luteolin Coloaded Dual-Functional Liposomes for Esophageal Cancer Therapy., PMID:40265971
Sexual dimorphism in the downregulation of extracellular matrix genes contributes to aortic stiffness in female mice., PMID:39873616
A Japanese family of hereditary diffuse gastric cancer with a germline pathogenic variant of CTNN1A detected via comprehensive genome profiling., PMID:39838246
Fortilin binds CTNNA3 and protects it against phosphorylation, ubiquitination, and proteasomal degradation to guard cells against apoptosis., PMID:39747445
A Systematic Review of Surgical and Pathological Outcomes in Patients With a CDH1 Mutation Undergoing Total Gastrectomy., PMID:39257226
Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders., PMID:39033378
CTNND1 is involved in germline predisposition to early-onset gastric cancer by affecting cell-to-cell interactions., PMID:38796558
Porocarcinomas with PAK1/2/3 fusions: a series of 12 cases., PMID:38785043
[Trends, challenges, and reflections on early-onset gastric cancer]., PMID:38778679
Identification of New Pathogenic Variants of Hereditary Diffuse Gastric Cancer., PMID:38605661
Expanding the genetics and phenotypes of ocular congenital cranial dysinnervation disorders., PMID:38585811
Functional Analysis of Membrane-Associated Scaffolding Tight Junction (TJ) Proteins in Tumorigenic Characteristics of B16-F10 Mouse Melanoma Cells., PMID:38255907
High-grade intraductal carcinoma of the parotid gland harboring CTNNA1::ALK rearrangement: Changes in genetic status using genetic testing during treatment with an ALK inhibitor., PMID:38018800
Mechanisms Underlying Rare Inherited Pediatric Retinal Vascular Diseases: FEVR, Norrie Disease, Persistent Fetal Vascular Syndrome., PMID:37947657
Focal nodular hyperplasia-like nodules arising in the setting of hepatic vascular disorders with portosystemic shunting show β-catenin activation., PMID:37806391
Integrated proteomics and phosphoproteomics analyses of esophageal cancer cells with different invasive abilities., PMID:37734435
α-Catenin acetylation is essential for its stability and blocks its tumor suppressor effects in breast cancer through Yap1., PMID:37679528
Autophagy regulation and protein kinase activity of PIK3C3 controls sertoli cell polarity through its negative regulation on SCIN (scinderin)., PMID:37450577
Recurrent PAK2 rearrangements in poroma with folliculo-sebaceous differentiation., PMID:37199682
CMTM7 inhibits breast cancer progression by regulating Wnt/β-catenin signaling., PMID:36829181
Hereditary Diffuse Gastric Cancer., PMID:36740198
Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study., PMID:36681091
Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer Cells., PMID:36674696
Differential Gene Expression of fresh tissue and patient-derived explants' matricellular proteins augment inflammatory breast cancer metastasis: the possible role of IL-6 and MCP-1., PMID:36592055
Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer., PMID:36484990
Damaging Mutations in AFDN Contribute to Risk of Nonsyndromic Cleft Lip With or Without Cleft Palate., PMID:36384317
Estrogen Regulates the Expression and Localization of YAP in the Uterus of Mice., PMID:36077170
First estimates of diffuse gastric cancer risks for carriers of CTNNA1 germline pathogenic variants., PMID:36038258
Familial and hereditary gastric cancer, an overview., PMID:35988963
[Hereditary gastric cancer syndromes and their association with specific histological subtypes]., PMID:35963792
The Analysis of the Ubiquitylomic Responses to Streptococcus agalactiae Infection in Bovine Mammary Gland Epithelial Cells., PMID:35923910
Hereditary Diffuse Gastric Cancer: Molecular Genetics, Biological Mechanisms and Current Therapeutic Approaches., PMID:35887173
Comprehensive Molecular Profiling of Oncocytic Salivary Gland Malignancies., PMID:35876752
Mutation spectrum in a cohort with familial exudative vitreoretinopathy., PMID:35876299
Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q., PMID:35617825
The Identification and Analysis of MicroRNAs Combined Biomarkers for Hepatocellular Carcinoma Diagnosis., PMID:35379158
CDH1 Germline Variants in a Tunisian Cohort with Hereditary Diffuse Gastric Carcinoma., PMID:35327954
Network Theoretical Approach to Explore Factors Affecting Signal Propagation and Stability in Dementia's Protein-Protein Interaction Network., PMID:35327643
Germline likely pathogenic variants in ataxia-telangiectasia-mutated gene in an Iranian family with hereditary diffuse gastric cancer without CDH1 mutation., PMID:34916374
Systems genetics analysis defines importance of TMEM43/LUMA for cardiac- and metabolic-related pathways., PMID:34766515
Proteomic Analysis of Exosomes during Cardiogenic Differentiation of Human Pluripotent Stem Cells., PMID:34685602
Hereditary diffuse gastric cancer (HDGC). An overview., PMID:34656755
Evaluating the Occurrence of Rare Variants in the Complement Factor H Gene in Patients With Early-Onset Drusen Maculopathy., PMID:34647987
The expression, localisation and interactome of pigeon CRY2., PMID:34645873
Aβ monomers protect lens epithelial cells against oxidative stress by upregulating CDC25B., PMID:34478836
Cancer predisposition and germline CTNNA1 variants., PMID:34425242
KRAS phosphorylation regulates cell polarization and tumorigenic properties in colorectal cancer., PMID:34333552
Glucose regulates expression of pro-inflammatory genes, IL-1β and IL-12, through a mechanism involving hexosamine biosynthesis pathway-dependent regulation of α-E catenin., PMID:34139004
Mammary Lobular Carcinoma-Like Salivary Gland Carcinoma: Report of a Rare Case., PMID:34115320
A mosaic PIK3CA variant in a young adult with diffuse gastric cancer: case report., PMID:34075207