Catalog No.
YHE05801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser258-Glu511
Predicted molecular weight
30.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P34932
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Heat shock 70-related protein APG-2, APG2, HSP70RY, Heat shock 70 kDa protein 4, HSPA4
Identification of single nucleotide polymorphisms (SNPs) associated with heat stress and milk production traits in Chinese holstein cows., PMID:40419962
Investigating the role of necroptosis in the immunological microenvironment of periodontitis., PMID:40402323
Identification of liver proteins as biomarker for postmortem diagnosis of heat stroke through proteomics., PMID:40379670
Cerebrospinal fluid HSP90AA1, HSPA4, and STUB1/CHIP levels in Alzheimer's disease, mild cognitive impairment, and frontotemporal dementia., PMID:40116694
Integrative analysis of serum proteomics and transcriptomics in hepatitis C., PMID:40082995
Mammalian heat shock protein A4 family ortholog Hsc70Cb is required for two phases of spermatogenesis in D. melanogaster., PMID:39991973
High-throughput screening of thermal tolerant candidate genes in the ivory shell (Babylonia areolata) based on the yeast strain INVSc1., PMID:39889586
Necroptosis-Related Gene Signature Predicts Prognosis in Patients with Advanced Ovarian Cancer., PMID:39858052
LINC01089 governs the miR-1287-5p/HSPA4 axis to negatively regulate osteogenic differentiation of mesenchymal stem cells., PMID:39679709
A Six-Gene Signature Related to Liquid-Liquid Phase Separation for Diagnosis of Alzheimer's Disease., PMID:39665604
HSPA4 Expression is Correlated with Melanoma Cell Proliferation, Prognosis, and Immune Regulation., PMID:39629045
HSPA4 Enhances BRSV Entry via Clathrin-Mediated Endocytosis Through Regulating the PI3K-Akt Signaling Pathway and ATPase Activity of HSC70., PMID:39599898
Characterization of HSP70 and HSP90 Gene Family in Takifugu fasciatus and Their Expression Profiles on Biotic and Abiotic Stresses Response., PMID:39596645
Elucidating gastric cancer mechanisms and therapeutic potential of Adociaquinone A targeting EGFR: A genomic analysis and Computer Aided Drug Design (CADD) approach., PMID:39434198
Bioinformatics data combined with single-cell analysis reveals patterns of immunoinflammatory infiltration and cell death in melanoma., PMID:39418727
Decoding the duration of fertility of laying chicken through phenotypic and proteomic evaluation., PMID:39311027
Effect of tannic acid on doxorubicin-induced cellular stress: Expression levels of heat shock genes in rat spleen., PMID:38945802
CEP55: Implications for Immunotherapy and Survival in Hepatocellular Carcinoma., PMID:38847172
Dynamically changed HSP70 after reperfusion following cerebral infarction in human and rats: correlation with p38 MAPK., PMID:38597327
HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer., PMID:38589927
Novel underlying genetic markers for asthenozoospermia due to abnormal spermatogenesis and reproductive organ inflammation., PMID:38476923
Mechanisms Involved in Therapeutic Effects of Scutellaria baicalensis Georgi in Oral Squamous Cell Carcinoma Based on Systems Biology and Structural Bioinformatics Approaches., PMID:38322303
Unveiling the potential of HSPA4: a comprehensive pan-cancer analysis of HSPA4 in diagnosis, prognosis, and immunotherapy., PMID:38305786
Prognostic and immunological roles of heat shock protein A4 in lung adenocarcinoma., PMID:38292659
HSP70 binds to specific non-coding RNA and regulates human RNA polymerase III., PMID:38266641
Targeting the NCAPD3 gene activates EGFR and ASNS as two pivotal contributors to gastric cancer progression., PMID:40406431
Hsp70 Gene Family in Sebastiscus marmoratus: The Genome-Wide Identification and Transcriptome Analysis under Thermal Stress., PMID:37761919
[STIP1 correlates with tumor immune infiltration and prognosis as a potential immunotherapy target: a pan-cancer bioinformatics analysis]., PMID:37488801
HSPA4 regulated glioma progression via activation of AKT signaling pathway., PMID:37339521
Distinct gene expression profiles underlie morphological and etiological differences in pediatric cataracts., PMID:37203095
Identification of glutamyl-prolyl-tRNA synthetase as a new therapeutic target in hepatocellular carcinoma via a novel bioinformatic approach., PMID:37201074
Heat shock protein 70 protects the lungs from hyperoxic injury in a neonatal rat model of bronchopulmonary dysplasia., PMID:37200358
Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer., PMID:37147328
Pyroptosis-related gene signature elicits immune response in rosacea., PMID:37086043
Role of CCT4/ErbB signaling in nephroblastoma: Implications for a biomarker of Wilms tumor., PMID:37058032
Acute Ozone-Induced Transcriptional Changes in Markers of Oxidative Stress and Glucocorticoid Signaling in the Rat Hippocampus and Hypothalamus Are Sex-Specific., PMID:37047376
Identification of candidate genomic regions for egg yolk moisture content based on a genome-wide association study., PMID:36918797
HSP70 Expression Signature in Renal Cell Carcinoma: A Clinical and Bioinformatic Analysis Approach., PMID:36833281
Identification of thioredoxin-1 as a biomarker of lung cancer and evaluation of its prognostic value based on bioinformatics analysis., PMID:36776308
Differentially Expressed Cell Cycle Genes and STAT1/3-Driven Multiple Cancer Entanglement in Psoriasis, Coupled with Other Comorbidities., PMID:36497125
Bioinformatics Analysis of Common Genetic and Molecular Traits and Association of Portal Hypertension with Pulmonary Hypertension., PMID:36312597
Basigin is necessary for normal decidualization of human uterine stromal cells., PMID:36303457
Identification and Analysis of Immune-Related Gene Signature in Hepatocellular Carcinoma., PMID:36292719
Chemoproteomic Approach for the Quantitative Identification of Arsenic-Binding Proteins., PMID:36269594
An immunogenic cell death-related regulators classification patterns and immune microenvironment infiltration characterization in intracranial aneurysm based on machine learning., PMID:36248807
Inhibition of DNAJC12 Inhibited Tumorigenesis of Rectal Cancer via Downregulating HSPA4 Expression., PMID:36185081
Fine-tuning of the Hsc70-based Human Protein Disaggregase Machinery by the Distinctive C-terminal Extension of Apg2., PMID:36167183
Gene Expression Characteristics of Tumor and Adjacent Non-Tumor Tissues of Pancreatic Ductal Adenocarcinoma (PDAC) In-Silico., PMID:35891953
A Comprehensive Stemness Gene Expression Analysis Signifies the Role of ABC Transporters and Molecular Chaperons in Determining the Fate of Human Neural Precursor Cells., PMID:35864646
Increased eHSP70-to-iHSP70 ratio in prediabetic and diabetic postmenopausal women: a biomarker of cardiometabolic risk., PMID:35767179
For research use only. Not for human or drug use.
