Catalog No.
YHE02001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu60-Ile227
Predicted molecular weight
21.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P32971
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD153, CD30-L, CD30L, Tumor necrosis factor ligand superfamily member 8, TNFSF8, CD30LG, CD30 ligand
Generation of antagonistic biparatopic anti-CD30 antibody from an agonistic antibody by precise epitope determination and utilization of structural characteristics of CD30 molecule., PMID:39958564
Specific immune response to M. tuberculosis and ability to in vitro control mycobacterial replication are not impaired in subjects with immune-mediated inflammatory disease and tuberculosis infection., PMID:39872515
CD30 influences germinal center B-cell dynamics and the expansion of IgG1-switched B cells., PMID:39420111
Senescence-associated T cells in immunosenescence and diseases., PMID:39320393
Elevated IL-15 levels in systemic lupus erythematosus: potential pathogenesis insight and therapeutic target., PMID:39217881
CD4+CD57+ senescent T cells as promoters of systemic lupus erythematosus pathogenesis and the therapeutic potential of senolytic BCL-2 inhibitor., PMID:38752316
Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays., PMID:37515759
Optimizing assessment of CD30 expression in Hodgkin lymphoma by controlling for low expression., PMID:37377225
Empowering drug off-target discovery with metabolic and structural analysis., PMID:37296102
CD30 co-stimulation drives differentiation of protective T cells during Mycobacterium tuberculosis infection., PMID:37097292
Several genetic variants associated with systemic sclerosis in a Chinese Han population., PMID:36301368
cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells., PMID:36130493
Mucosal Vaccination with Cyclic Dinucleotide Adjuvants Induces Effective T Cell Homing and IL-17-Dependent Protection against Mycobacterium tuberculosis Infection., PMID:34965963
CD153/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury., PMID:34813503
CD30L+ classical monocytes play a pro-inflammatory role in the development of ulcerative colitis in patients., PMID:34329889
Development of antibacterial compounds that constrain evolutionary pathways to resistance., PMID:34279221
Partial recovery of senescence in circulating follicular helper T cells after Dasatinib treatment., PMID:33631598
Combination blockade of OX40L and CD30L inhibits allergen-driven memory TH2 cell reactivity and lung inflammation., PMID:33160971
Disease extent and anti-tubercular treatment response correlates with Mycobacterium tuberculosis-specific CD4 T-cell phenotype regardless of HIV-1 status., PMID:33005414
Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis., PMID:32678272
The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice., PMID:32424156
Classical Hodgkin lymphoma cells may promote an IL-17-enriched microenvironment., PMID:31304817
Alterations in immune and renal biomarkers among workers occupationally exposed to low levels of trichloroethylene below current regulatory standards., PMID:30971425
CD30 ligand deficiency accelerates glioma progression by promoting the formation of tumor immune microenvironment., PMID:30952099
Severe Progressive Mycobacterium avium Complex Infection Associated With Brentuximab Vedotin Therapy., PMID:30423147
Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression., PMID:30202016
CD30 Is Highly Expressed in Chronic Obstructive Pulmonary Disease and Induces the Pulmonary Vascular Remodeling., PMID:29984229
Correlates of immune exacerbations in leprosy., PMID:29950273
Tumor-stage mycosis fungoides in palmoplantar localization with large-cell transformation and partial CD30 expression shows complete response to brentuximab vedotin., PMID:29512830
Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling., PMID:29431186
Cutaneous intravascular CD30+ T-cell pseudolymphoma occurring in a regressing keratoacanthoma., PMID:29369392
Case of primary cutaneous anaplastic large cell lymphoma misdiagnosed as squamous cell carcinoma by pseudocarcinomatous hyperplasia., PMID:29314194
T Cell Transcriptomes from Paroxysmal Nocturnal Hemoglobinuria Patients Reveal Novel Signaling Pathways., PMID:28630090
Physiologic Thymic Involution Underlies Age-Dependent Accumulation of Senescence-Associated CD4+ T Cells., PMID:28539430
CD30 expression in extranodal natural killer/T-cell lymphoma, nasal type among 622 cases of mature T-cell and natural killer-cell lymphoma at a single institution in South China., PMID:28486951
The role of CD30 and CD153 (CD30L) in the anti-mycobacterial immune response., PMID:28061955
Obesity accelerates T cell senescence in murine visceral adipose tissue., PMID:27820698
Undifferentiated Nasopharyngeal Carcinoma Mimicking Hodgkin Lymphoma With CD30 Expression., PMID:27543511
Osteopontin in Spontaneous Germinal Centers Inhibits Apoptotic Cell Engulfment and Promotes Anti-Nuclear Antibody Production in Lupus-Prone Mice., PMID:27534552
Association of CD30 transcripts with Th1 responses and proinflammatory cytokines in patients with end-stage renal disease., PMID:26970513
[Anaplastic large-cell lymphoma CD30(+) ALK(+)]., PMID:26620365
Elevated Serum Levels of Soluble CD30 in Ankylosing Spondylitis Patients and Its Association with Disease Severity-Related Parameters., PMID:26273636
Evaluation of NF-κB subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions., PMID:26111978
Characterization of CD30/CD30L(+) Cells in Peripheral Blood and Synovial Fluid of Patients with Rheumatoid Arthritis., PMID:26090498
A CD153+CD4+ T follicular cell population with cell-senescence features plays a crucial role in lupus pathogenesis via osteopontin production., PMID:25972477
Association of TNFSF8 regulatory variants with excessive inflammatory responses but not leprosy per se., PMID:25320285
CD30 in systemic mastocytosis., PMID:24745678
Protrusion-guided extracellular vesicles mediate CD30 trans-signalling in the microenvironment of Hodgkin's lymphoma., PMID:24659185
CD30-negative lymphomatoid papulosis type D in an elderly man., PMID:24394303
CD30L/CD30 is critical for maintenance of IL-17A-producing γδ T cells bearing Vγ6 in mucosa-associated tissues in mice., PMID:23549449
For research use only. Not for human or drug use.
