Catalog No.
YHD96601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys146
Predicted molecular weight
19.27 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31751
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PKB beta, Protein kinase Akt-2, AKT2, Protein kinase B beta, RAC-beta serine/threonine-protein kinase, RAC-PK-beta
Anti-GBM effects of polyphenolic extract from Avicennia marina., PMID:40490234
Mutational analysis and protein expression of PI3K/AKT pathway in four mucinous cystadenocarcinoma of the breast., PMID:40437613
TP53 Mutations and Phosphatidylinositol 3-Kinase/AKT Pathway Alterations Are Key Determinants of Breast Cancer Outcome Independent of Subtype and Stage., PMID:40403210
A Multi-Level Study on the Anti-Lung Cancer Mechanism of Peiminine, a Key Component of Fritillaria ussuriensis Maxim.: Integrating Quality Analysis, Network Pharmacology, Bioinformatics Analysis, and Experimental Validation., PMID:40331978
Downregulation of Akt induces proximal tubule epithelial cell apoptosis via Foxo-1-BIM pathway in proteinuric states., PMID:40313745
In-silico investigation integrated with machine learning to identify potential inhibitors targeting AKT2: Key driver of cancer cell progression and metastasis., PMID:40305999
Clinical-Genetic Approach to Conditions with Macrocephaly and ASD/Behaviour Abnormalities: Variants in PTEN and PPP2R5D Are the Most Recurrent Gene Mutations in a Patient-Oriented Diagnostic Strategy., PMID:40282429
Loss of neurofibromin induces inflammatory macrophage phenotypic switch and retinal neovascularization via GLUT1 activation., PMID:40279245
4-fluorophenylacetamide acetyl coumarin induces pro-inflammatory M1 macrophage polarization and suppresses the immunosuppressive M2 phenotype through PI3k/AKT/NF-κB modulation., PMID:40266432
Discovery of novel PI3KC2γ inhibitors with high potency, selectivity, and favorable pharmacokinetics for glycogen metabolism regulation., PMID:40262302
A Major Latex Protein-Encoding Gene from Populus simonii × P. nigra (PsnMLP328) Contributes to Defense Responses to Salt and Cadmium Stress., PMID:40244218
Cell-intrinsic insulin signaling defects in human iPS cell-derived hepatocytes in type 2 diabetes., PMID:40231468
Exosome-shuttled miR-5121 from A2 astrocytes promotes BSCB repair after traumatic SCI by activating autophagy in vascular endothelial cells., PMID:40229869
Covariation of scleral remodeling and PI3K/Akt signaling pathway in experimental myopia., PMID:40216914
Isoform specific regulation of osteopontin by AKT2 in hepatocytes and livers., PMID:40216173
Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling., PMID:40208790
Study on mechanism of iridoid glycosides derivatives from Fructus Gardeniae in treatment of hepatic encephalopathy by network pharmacology and molecular docking technology., PMID:40184133
Establishment and characterization of novel cancer cachexia-inducing cell line, Aku60GC, of scirrhous gastric cancer., PMID:40178664
Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment., PMID:40139836
Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model., PMID:40129297
HIIT may ameliorate inter-organ crosstalk between liver and hypothalamus of HFD-induced MAFLD rats; A two-phase study to investigate the effect of exercise intensity as a stressor., PMID:40120709
Tiliroside from Lagopsis supina Ameliorates Myocardial Ischemia Injury in Zebrafish by Activating the kdr-Mediated PI3K-Akt and MAPK Signaling Pathways., PMID:40076931
Persistent Postirradiation Skeletal Muscle Protein and Insulin Sensitivity Changes in Nonhuman Primates., PMID:40053841
AKT activation triggers Rab14-mediated ADAM10 translocation to the cell surface in human aortic endothelial cells., PMID:40032916
Comprehensive analysis of the potential mechanism of gansui in blocking non-small cell lung cancer progression., PMID:40029169
Akt2 inhibition alleviates temporomandibular joint osteoarthritis by preventing subchondral bone loss., PMID:40016746
Glutamatergic argonaute2 promotes the formation of the neurovascular unit in mice., PMID:39999211
Activated NETosis of bone marrow neutrophils up-regulates macrophage osteoclastogenesis via cGAS-STING/AKT2 pathway to promote osteoporosis., PMID:39988126
The Abnormal ERα-miRNA Cross-Talk in AD-Affected Human Hippocampus: A Bioinformatics Perspective., PMID:39966328
ATF3 Knockdown Exacerbates Astrocyte Activation by Inhibiting Phosphorylation of Drp1 in Ischemic Stroke., PMID:39963286
TCL1A in naïve B cells as a therapeutic target for type 1 diabetes., PMID:39946833
βIV spectrin abundancy, cellular distribution and sensitivity to AKT/GSK3 regulation in schizophrenia., PMID:39920295
Structural requirements of isoform-specific inhibitors of Akt: Implications in the development of effective cancer treatment strategies., PMID:39904143
IGF2BP1 stabilizes Akt2 mRNA to promote glucose metabolism and maintain spermatogonial proliferation., PMID:39902819
Identifying Key Biomarkers Related to Immune Response in the Progression of Diabetic Kidney Disease: Mendelian Randomization Combined With Comprehensive Transcriptomics and Single-Cell Sequencing Analysis., PMID:39871959
A dynamic co-expression approach reveals Gins2 as a potential upstream modulator of HNSCC metastasis., PMID:39865116
PTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers., PMID:39841180
Roles of oolong tea extracts in the protection against Staphylococcus aureus infection in Caenorhabditis elegans., PMID:39801228
[High expression of CRTAC1 promotes proliferation, migration and immune cell infiltration of gastric cancer by regulating the PI3K/AKT signaling pathway]., PMID:39725632
Evaluation of the Potential Hypoglycaemic Properties of Mimusops zeyheri Sond. and Aloe marlothii A.Berger, Two Plants Used by Traditional Healers in South Africa., PMID:39683116
MicroRNAs Dependent G-ELNs Based Intervention Improves Glucose and Fatty Acid Metabolism While Protecting Pancreatic β-Cells in Type 2 Diabetic Mice., PMID:39648555
Jiawei Qi Gong Wan improves liver fibrosis and inflammation in PCOS mice via the Akt2-FoxO1 and YAP/TAZ signaling pathways., PMID:39616732
Association between insulin-associated gene polymorphisms and new-onset diabetes mellitus in statin-treated patients., PMID:39614667
p21Waf1/Cip1 Is a Novel Downstream Target of 40S Ribosomal S6 Kinase 2., PMID:39594738
Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis., PMID:39566466
p70S6K as a Potential Anti-COVID-19 Target: Insights from Wet Bench and In Silico Studies., PMID:39513867
Proteomics and Metabolomics Study on the Responses of Sertoli Cells Infected With Brucella and Its bvfA-Deletion Strains., PMID:39512196
Epigenetic modification of IGF2/H19 imprinting control region regulates PGC-1α/PI3K/AKT2 pathway in a rat model of intrauterine growth restriction., PMID:39497357
EZH2 contributes to sepsis-induced acute lung injury through regulating macrophage polarization., PMID:39471914
The effect of Helicobacter pylori-derived extracellular vesicles on glucose metabolism and induction of insulin resistance in HepG2 cells., PMID:39431628
For research use only. Not for human or drug use.
