Catalog No.
YHD88601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn45-Lys196
Predicted molecular weight
18.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30405
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CypD, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, Cyclophilin D, Cyclophilin F, CYP3, CyP-M, Rotamase F, PPIF, CyP-D, PPIase F, Mitochondrial cyclophilin
CYPD limits HR+ mammary carcinogenesis in mice., PMID:40494873
Discovery of novel ancestry specific genes for androgens and hypogonadism in Million Veteran Program Men., PMID:40316537
Oleogels based on protein fibrils-hordein-xanthan gum complexes: Formation, structure, and physicochemical properties., PMID:40263855
Cyclophilin D knockdown/knockout promotes microglia M2 polarization by inhibiting STAT1 to alleviate neuroinflammation in neonatal white matter injury., PMID:40132721
Cyclophilin D (CypD) ablation prevents neurodegeneration and cognitive damage induced by caspase-3 cleaved tau., PMID:40023297
Depletion of Mitochondrial Cyclophilin D in Endothelial and Smooth Muscle Cells Attenuates Vascular Dysfunction and Hypertension., PMID:39919759
Genetic Markers of Postmortem Brain Iron., PMID:39918201
Biological characteristics, immune infiltration and drug prediction of PANoptosis related genes and possible regulatory mechanisms in inflammatory bowel disease., PMID:39814753
Senolysis by GLS1 Inhibition Ameliorates Kidney Aging by Inducing Excessive mPTP Opening Through MFN1., PMID:39697097
The adenine nucleotide translocase family underlies cardiac ischemia-reperfusion injury through the mitochondrial permeability pore independently of cyclophilin D., PMID:39661674
Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction., PMID:39623043
SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells., PMID:39524354
N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase., PMID:39528709
Role of the PGAM5-CypD mitochondrial pathway in methylglyoxal-induced bone loss in diabetic osteoporosis., PMID:39510433
Comparison of chromatin accessibility remodeling of granulosa cells in patients with endometrioma or pelvic/tubal infertility., PMID:39485574
Cyclophilin D plays a critical role in the survival of senescent cells., PMID:39448884
Cyclophilin D, regulator of the mitochondrial permeability transition, impacts bone development and fracture repair., PMID:39299628
Neutrophil PPIF exacerbates lung ischemia-reperfusion injury after lung transplantation by promoting calcium overload-induced neutrophil extracellular traps formation., PMID:39236457
Mitochondrial permeability transition dictates mitochondrial maturation upon switch in cellular identity of hematopoietic precursors., PMID:39122870
Cyclophilin D induces necrotic core formation by mediating mitochondria-associated macrophage death in advanced atherosclerotic lesions., PMID:38972156
Dissecting prostate Cancer: Single-Cell insight into Macrophage Diversity, molecular Prognosticators, and the role of Peptidylprolyl Isomerase F., PMID:38959543
Nynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening., PMID:38955185
Mitochondrial CypD Acetylation Promotes Endothelial Dysfunction and Hypertension., PMID:38639088
Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH., PMID:38573968
Role of the mitochondrial protein cyclophilin D in skin wound healing and collagen secretion., PMID:38564292
Anesthetic Sevoflurane Induces Enlargement of Dendritic Spine Heads in Mouse Neurons via Tau-Dependent Mechanisms., PMID:38507523
Differential responses of selectively bred mussels (Perna canaliculus) to heat stress-survival, immunology, gene expression and microbiome diversity., PMID:38425477
Identification of neutrophil extracellular traps and crosstalk genes linking inflammatory bowel disease and osteoporosis by integrated bioinformatics analysis and machine learning., PMID:38155235
Mitochondrial permeability transition regulator, cyclophilin D, is transcriptionally activated by C/EBP during adipogenesis., PMID:37949231
CypD induced ROS output promotes intracranial aneurysm formation and rupture by 8-OHdG/NLRP3/MMP9 pathway., PMID:37717465
ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy., PMID:37624892
Molecular signature associated with cladribine treatment in patients with multiple sclerosis., PMID:37559720
Neutrophil extracellular trap is an important connection between hemodialysis and acute myocardial infarction., PMID:37246754
CyclosporinA Derivative as Therapeutic Candidate for Alport Syndrome by Inducing Mutant Type IV Collagen Secretion., PMID:37143203
Identification of novel immune subtypes and potential hub genes of patients with psoriasis., PMID:36890558
Dawn-to-dusk dry fasting induces anti-atherosclerotic, anti-inflammatory, and anti-tumorigenic proteome in peripheral blood mononuclear cells in subjects with metabolic syndrome., PMID:36506940
Tandem mass tag-based proteomic profiling revealed potential therapeutic targets and mechanisms of liraglutide for the treatment of impaired glucose tolerance., PMID:36452319
Cyclin B1 expression as an independent prognostic factor for lung adenocarcinoma and its potential pathways., PMID:36420081
Chaperoning activity of the cyclophilin family prevents tau aggregation., PMID:36305768
Cinnamtannin B-1 Inhibits the Progression of Osteosarcoma by Regulating the miR-1281/PPIF Axis., PMID:36273900
Global landscape of protein complexes in postprandial-state livers from diet-induced obese and lean mice., PMID:36099783
Mitochondrial Permeability Transition in Stem Cells, Development, and Disease., PMID:35739412
Transcriptional regulation of cyclophilin D by BMP/Smad signaling and its role in osteogenic differentiation., PMID:35635445
Regulation of p53 Function by Formation of Non-Nuclear Heterologous Protein Complexes., PMID:35204825
Characterization of DNA methylation as well as mico-RNA expression and screening of epigenetic markers in adipogenesis., PMID:35168604
Genomewide Association Analyses of Lactation Persistency and Milk Production Traits in Holstein Cattle Based on Imputed Whole-Genome Sequence Data., PMID:34828436
Alisporivir Treatment Alleviates Mitochondrial Dysfunction in the Skeletal Muscles of C57BL/6NCrl Mice with High-Fat Diet/Streptozotocin-Induced Diabetes Mellitus., PMID:34502433
Nampt controls skeletal muscle development by maintaining Ca2+ homeostasis and mitochondrial integrity., PMID:34119711
Genome-wide enhancer maps link risk variants to disease genes., PMID:33828297
Genetic Approach to Elucidate the Role of Cyclophilin D in Traumatic Brain Injury Pathology., PMID:33498273
For research use only. Not for human or drug use.
