Catalog No.
YHD87701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn17-Ser231
Predicted molecular weight
26.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30260
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ANAPC3, Cell division cycle protein 27 homolog, CDC27, APC3, Anaphase-promoting complex subunit 3, CDC27Hs, D0S1430E, CDC27 homolog, D17S978E, H-NUC
Allelic expression patterns of imprinted and non-imprinted genes in cancer cell lines from multiple histologies., PMID:40414875
CDC6 Inhibits CDK1 Activity in MII-Arrested Oocyte Cell-Free Extract., PMID:40362544
Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing., PMID:40341598
Studies on the regulation of E3 ubiquitin ligase APC3 and its interacting proteins on the tetraspore formation and release in Gracilariopsis lemaneiformis (Rhodophyta)., PMID:40169068
APC/C-mediated ubiquitylation of extranucleosomal histone complexes lacking canonical degrons., PMID:40089476
Inhibition of CDC27 O-GlcNAcylation coordinates the antitumor efficacy in multiple myeloma through the autophagy-lysosome pathway., PMID:39984622
Organoid modeling identifies USP3-AS1 as a novel promoter in colorectal cancer liver metastasis through increasing glucose-driven histone lactylation., PMID:39837984
LNC_000280 could be a new positive factor in the proliferation and differentiation of myoblasts: A prospective study., PMID:39602431
Proteomic and serological markers for diagnosing cardia gastric cancer and precursor lesions in a Chinese population., PMID:39455684
Implications of ITCH-mediated ubiquitination of SIX1 on CDC27-cyclinB1 signaling in nasopharyngeal carcinoma., PMID:39406717
CDC27 gene expression patterns as a potential biomarker in Acute Leukemia., PMID:39073611
Mis-splicing of Mitotic Regulators Sensitizes SF3B1-Mutated Human HSCs to CHK1 Inhibition., PMID:38856693
The C-terminal disordered loop domain of Apc8 unlocks APC/C mitotic activation., PMID:38776225
Functional and Genetic Analyses Unveil the Implication of CDC27 in Hemifacial Microsomia., PMID:38731925
Activation of the Anaphase Promoting Complex Restores Impaired Mitotic Progression and Chemosensitivity in Multiple Drug-Resistant Human Breast Cancer., PMID:38730707
Predictive Modeling of Proteins Encoded by a Plant Virus Sheds a New Light on Their Structure and Inherent Multifunctionality., PMID:38254661
Mutation Profile via Next-Generation Sequencing in Patients with Colorectal Adenocarcinoma and Its Clinicopathological Correlation., PMID:37737217
Mad2B forms a complex with Cdc20, Cdc27, Rev3 and Rev1 in response to cisplatin-induced DNA damage., PMID:37641805
Prolactin Regulates Testicular Gene Expression and Cell Cycle Processes Predominantly via JAK2/STAT5 Pathway in the Male Rat., PMID:37232379
LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway., PMID:36994860
Shared peripheral blood biomarkers for Alzheimer's disease, major depressive disorder, and type 2 diabetes and cognitive risk factor analysis., PMID:36994393
Discovery of differentially expressed novel miRNAs in breast normal cells and their putative targets., PMID:36680668
MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration., PMID:36543134
Nuclear-localized CTEN is a novel transcriptional regulator and promotes cancer cell migration through its downstream target CDC27., PMID:36399312
Candidate genes for infertility: an in-silico study based on cytogenetic analysis., PMID:35918717
Genotypes of Papillary Thyroid Carcinoma With High Lateral Neck Metastasis in Chinese Population., PMID:35865459
A paediatric dysembryoplastic neuroepithelial tumour (DNET) with deregulated stem cell markers: a case report., PMID:35800288
Circ_0000775 promotes the migration, invasion and EMT of hepatic carcinoma cells by recruiting IGF2BP2 to stabilize CDC27., PMID:35561648
A Novel Gene CDC27 Causes SLE and Is Associated With the Disease Activity., PMID:35418986
Circular RNA circSLC8A1 inhibits the proliferation and invasion of glioma cells through targeting the miR-214-5p/CDC27 axis., PMID:35098413
Analysis of expression profiles and bioinformatics suggests that plasma exosomal circular RNAs may be involved in ischemic stroke in the Chinese Han population., PMID:35067794
Integrated Analysis of miRNA-mRNA Regulatory Networks Associated with Osteonecrosis of the Femoral Head., PMID:34422080
Dynamic regulation of mitotic ubiquitin ligase APC/C by coordinated Plx1 kinase and PP2A phosphatase action on a flexible Apc1 loop., PMID:34291488
The importance of CDC27 in cancer: molecular pathology and clinical aspects., PMID:33750395
Identification of a Ubiquitination-Related Gene Risk Model for Predicting Survival in Patients With Pancreatic Cancer., PMID:33414811
Differential Expression and Bioinformatics Analysis of circRNA in Non-small Cell Lung Cancer., PMID:33329727
A novel long non-coding RNA RP11-286H15.1 represses hepatocellular carcinoma progression by promoting ubiquitination of PABPC4., PMID:33259899
Cyclin B3 activates the Anaphase-Promoting Complex/Cyclosome in meiosis and mitosis., PMID:33137813
Identification of the Key Genes Involved in the Effect of Folic Acid on Endothelial Progenitor Cell Transcriptome of Patients with Type 1 Diabetes., PMID:33029194
Genetic Features of Lung Adenocarcinoma with Ground- Glass Opacity: What Causes the Invasiveness of Lung Adenocarcinoma?, PMID:33020345
Hsa_circ_0044226 knockdown attenuates progression of pulmonary fibrosis by inhibiting CDC27., PMID:32710728
Clinical Characteristics and Mutation Analyses of Ovarian Sertoli-Leydig Cell Tumors., PMID:32557933
Effects of tosyl-l-arginine methyl ester (TAME) on the APC/c subunits: An in silico investigation for inhibiting cell cycle., PMID:32066079
PP2A-B56 binds to Apc1 and promotes Cdc20 association with the APC/C ubiquitin ligase in mitosis., PMID:31825153
Characterization and validation of somatic mutation spectrum to reveal heterogeneity in gastric cancer by single cell sequencing., PMID:36659713
CDC27 Facilitates Gastric Cancer Cell Proliferation, Invasion and Metastasis via Twist-Induced Epithelial-Mesenchymal Transition., PMID:30308498
Recurrent Mutations in APC and CTNNB1 and Activated Wnt/β-catenin Signaling in Intraductal Papillary Neoplasms of the Bile Duct: A Whole Exome Sequencing Study., PMID:30212390
Germline and somatic variations influence the somatic mutational signatures of esophageal squamous cell carcinomas in a Chinese population., PMID:30012096
Whole-exome sequencing identifies unique mutations and copy number losses in calcifying fibrous tumor of the pleura: report of 3 cases and review of the literature., PMID:29689243
Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis., PMID:29618731
For research use only. Not for human or drug use.
