Catalog No.
YHD85501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu332
Predicted molecular weight
33.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29966
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Myristoylated alanine-rich C-kinase substrate, 80K-L protein, PKCSL, Protein kinase C substrate, 80 kDa protein, light chain, PRKCSL, MACS, MARCKS
FGF21 alleviates α-II-spectrin breakdown in a model of oxygen-glucose deprivation and modulates global protein phosphorylation in hippocampal neurons., PMID:40447258
Intrinsic Disorder and Phase Separation Coordinate Exocytosis, Motility, and Chromatin Remodeling in the Human Acrosomal Proteome., PMID:40407495
Activation of Marck-like Genes and Proteins During Initial Phases of Regeneration in the Amputated Tail and Limb of the Lizard Podarcis muralis., PMID:40265370
Neurotrophic factor biomarkers for ischemic stroke diagnosis and mechanistic insights., PMID:40195336
MARCKS protein is a potential target in a naturally occurring equine model of neutrophilic asthma., PMID:40176021
Study of Intracellular Peptides of the Central Nervous System of Zebrafish (Danio rerio) in a Parkinson's Disease Model., PMID:40076641
Ca2+/calmodulin and protein kinase C (PKC) reverse the vesicle fusion arrest by unmasking PIP2., PMID:40009675
Activity and function of the endothelial sodium channel is regulated by the effector domain of MARCKS-like protein 1 in mouse aortic endothelial cells., PMID:39982423
Oocyte transcriptomes and follicular fluid proteomics of ovine atretic follicles reveal the underlying mechanisms of oocyte degeneration., PMID:39893388
Spatiotemporal distribution of PKCα, PIP3, Moesin, Cdc42, MARCKS, Scriblle, and Arf6 before directed cell migration in monolayers., PMID:39892054
Allergen-induced activation of epithelial P2Y2 receptors promotes adenosine triphosphate exocytosis and type 2 immunity in airways., PMID:39863058
Membrane Surface Charge, Phospholipids, and Protein Localization., PMID:39838010
Lack of TRIC-B dysregulates cytoskeleton assembly, trapping β-catenin at osteoblast adhesion sites., PMID:39834042
Machine Learning Reveals Aneuploidy Characteristics in Cancers: The Impact of BEX4., PMID:39735979
Marcks overexpression in retinal ganglion cells promotes optic nerve regeneration., PMID:39695101
Role for the PIP2-binding protein myristoylated alanine-rich C-kinase substrate in vascular tissue: A novel therapeutic target for cardiovascular disease., PMID:39691873
Marcks and Marcks-like 1 proteins promote spinal cord development and regeneration in Xenopus., PMID:39665418
Dapagliflozin Suppresses High Glucose-Induced Proliferation, Oxidative Stress, and Fibrosis by Reducing Mettl3-Induced m6A Modification in Marcks mRNA., PMID:39560681
Milk Fat Globules: 2024 Updates., PMID:39474586
Identification of Aberrant Expression of Gemcitabine-Targeting Proteins in Drug-Resistant Cells Using an Activity-Based Gemcitabine Probe., PMID:39465385
Mycobacterium avium inhibits protein kinase C and MARCKS phosphorylation in human cystic fibrosis and non-cystic fibrosis cells., PMID:39413095
Integration of bioinformatics and multi-layered experimental validation reveals novel functions of acetylation-related genes in intervertebral disc degeneration., PMID:39349110
A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells., PMID:39343539
Citrus pectin modulates chicken peripheral blood mononuclear cell proteome in vitro., PMID:39288719
Stretch triggers microtubule stabilization and MARCKS-dependent membrane incorporation in the shaft of embryonic axons., PMID:39265571
Spatial characterization and stratification of colorectal adenomas by deep visual proteomics., PMID:39252972
Inhibition of MARCKS phosphorylation attenuates of dendritic cell migration in a murine model of acute asthma., PMID:39111683
Activity and function of the endothelial sodium channel is regulated by the effector domain of MARCKS like protein 1 in mouse aortic endothelial cells., PMID:38979152
A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo., PMID:38837880
Exosomes derived from pulmonary metastatic sites enhance osteosarcoma lung metastasis by transferring the miR-194/215 cluster targeting MARCKS., PMID:38799644
CircTRIM1 encodes TRIM1-269aa to promote chemoresistance and metastasis of TNBC via enhancing CaM-dependent MARCKS translocation and PI3K/AKT/mTOR activation., PMID:38755678
PIP2 Is An Electrostatic Catalyst for Vesicle Fusion by Lowering the Hydration Energy: Arresting Vesicle Fusion by Masking PIP2., PMID:38717305
LINC01133 regulates MARCKS expression via sponging miR-30d-5p to promote the development of lung squamous cell carcinoma., PMID:38599002
Lipopolysaccharide Regulates the Macrophage RNA-Binding Proteome., PMID:38527097
MARCKS Inhibition Alters Bovine Neutrophil Responses to Salmonella Typhimurium., PMID:38398044
A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo., PMID:38328061
Single-cell data revealed CD14-type and FCGR3A-type macrophages and relevant prognostic factors for predicting immunotherapy and prognosis in stomach adenocarcinoma., PMID:38274323
Integrating single-cell and bulk RNA sequencing data unveils antigen presentation and process-related CAFS and establishes a predictive signature in prostate cancer., PMID:38221616
Antitumor effects of chemically modified miR-143 lipoplexes in a mouse model of pelvic colorectal cancer via myristoylated alanine-rich C kinase substrate downregulation., PMID:38213952
Binding-induced lipid domains: Peptide-membrane interactions with PIP2 and PS., PMID:38142298
Emerging role of microRNAs as regulators of protein kinase C substrate MARCKS and MARCKSL1 in cancer., PMID:38104645
Multisolitons-like patterns in a one-dimensional MARCKS protein cyclic model., PMID:38096977
Targeting N-Myristoylation Through NMT2 Prevents Cardiac Hypertrophy and Heart Failure., PMID:38094695
MARCKS and PI(4,5)P2 reciprocally regulate actin-based dendritic spine morphology., PMID:38088877
Development and evaluation of a risk score model based on a WNT score gene-associated signature for predicting the clinical outcome and the tumour microenvironment of hepatocellular carcinoma., PMID:38054921
Correction to: MARCKS regulates tonic and chronic active B cell receptor signaling., PMID:38040959
Far-Infrared Ameliorates Pb-Induced Renal Toxicity via Voltage-Gated Calcium Channel-Mediated Calcium Influx., PMID:37958813
Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders., PMID:37951597
Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages., PMID:37949888
The Effect of Gene Editing by CRISPR-Cas9 of miR-21 and the Indirect Target MMP9 in Metastatic Prostate Cancer., PMID:37834295
For research use only. Not for human or drug use.
