Catalog No.
YHD85101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val11-His346
Predicted molecular weight
41.20 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29728
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
p69 OAS / p71 OAS, OAS2, 2-5A synthase 2, p69OAS / p71OAS, 2'-5'-oligoadenylate synthase 2, (2-5')oligo(A) synthase 2
Finding a foothold to fight: New insights into the viral RNA sensing and activation mechanism of OAS2., PMID:40480194
Structural basis for OAS2 regulation and its antiviral function., PMID:40412389
Identification immune-related hub genes in diagnosing atherosclerosis with ischemic stroke through comprehensive bioinformatics analysis and machine learning., PMID:40371070
Verification of biological markers of subacute cutaneous lupus erythematosus via TMT labelling proteomics combined with transcriptome data., PMID:40323689
Robust antiviral innate immune response and miRNA regulatory network were identified in ZIKV-infected cells: implications in the pathogenesis of ZIKV infection., PMID:39955676
Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation., PMID:39921639
Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1-infected women is associated with lower viral loads., PMID:39902043
Heterogeneity of OAS family expression in tuberculosis and the impact of different sample selection: a comprehensive analysis., PMID:39864306
Aging Selectively Alters PRR and ISG Expression in Endo- and Ecto-Cervical Stromal Fibroblasts From the Human Female Reproductive Tract., PMID:39777771
The Sdp-SH3b2 domain contained in Lactobacillus johnsonii N6.2-derived extracellular vesicles inhibit murine norovirus replication., PMID:39712028
Investigating the clinical significance of OAS family genes in breast cancer: an in vitro and in silico study., PMID:39633486
Analysis of the relationships between interferon-stimulated genes and anti-SSA/Ro 60 antibodies in primary Sjögren's syndrome patients via multiomics and machine learning methods., PMID:39577221
Identification of significant hub genes and pathways associated with metastatic breast cancer and tolerogenic dendritic cell via bioinformatics analysis., PMID:39549529
Proteomic profiling of oral squamous cell carcinoma tissues reveals altered immune-related proteins: implications for personalized therapy., PMID:39523852
Genetic variants of LRRC8C, OAS2, and CCL25 in the T cell exhaustion-related genes are associated with non-small cell lung cancer survival., PMID:39416786
Evaluation of Laser Intensity Effect on Photodynamic Therapy Efficacy., PMID:39193105
LncRNA XIST/miR-381-3P/STAT1 axis as a potential biomarker for lupus nephritis., PMID:39126180
A comparative analysis of RNA-Seq and NanoString technologies in deciphering viral infection response in upper airway lung organoids., PMID:38957806
Profiling of Early Immune Responses to Vaccination Using THP-1-Derived Dendritic Cells., PMID:38791547
Comparative transcriptomic analysis reveals the molecular changes of acute pancreatitis in experimental models., PMID:38681131
Endometrial responsiveness to interferon-tau and its association with subsequent reproductive performance in dairy heifers., PMID:38642656
Distinct domain organization and diversity of 2'-5'-oligoadenylate synthetases., PMID:38603810
Age-related transcript changes in type I interferon signaling in children and adolescents with long COVID., PMID:38522030
Label-free quantitative proteomics reveals the mechanisms of Aurora kinase B in renal cell carcinoma., PMID:38516642
Screening of Genes Associated with Immune Infiltration of Discoid Lupus Erythematosus Based on Weighted Gene Co-expression Network Analysis., PMID:38451400
Redox regulation of m6A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes., PMID:38409327
Expression network analysis of bovine skin infested with Rhipicephalus australis identifies pro-inflammatory genes contributing to tick susceptibility., PMID:38388834
Recognizing the role of Epstein-Barr virus in gastric cancer: transcriptomic insights into malignancy modulation., PMID:38355581
Dysregulated immune and metabolic pathways are associated with poor survival in adult acute myeloid leukemia with CEBPA bZIP in-frame mutations., PMID:38253683
Transcriptomic Changes in Response to Form of Selenium on the Interferon-Tau Signaling Mechanism in the Caruncular Tissue of Beef Heifers at Maternal Recognition of Pregnancy., PMID:38139156
AT1R autoantibody promotes phenotypic transition of smooth muscle cells by activating AT1R-OAS2., PMID:38092283
Identification of interferon-stimulated genes with modulated expression during hepatitis E virus infection in pig liver tissues and human HepaRG cells., PMID:38058490
Cytosolic nucleic acid sensing and mitochondrial transcriptomic changes as early triggers of metabolic disease in db/db mice., PMID:37979047
Activation of Toll-like receptor 3 inhibits HIV infection of human iPSC-derived microglia., PMID:37933090
Shared biomarkers and immune cell infiltration signatures in ulcerative colitis and nonalcoholic steatohepatitis., PMID:37898694
Regulation of microglia-mediated inflammation by host lncRNA Gm20559 upon flaviviral infection., PMID:37801852
Bioinformatics and systems biology analysis revealed PMID26394986-Compound-10 as potential repurposable drug against covid-19., PMID:37534820
Downregulation of Microcephaly-Causing Genes as a Mechanism for ZIKV Teratogenesis: A Meta-analysis of RNA-Seq Studies., PMID:37428363
Characterization of virus-mediated autoimmunity and the consequences for pathological process in patients with systemic lupus erythematosus., PMID:37369873
DNA methyltransferase inhibitor 5-azacytidine enhances neuroblastoma cell lysis by an oncolytic parainfluenza virus., PMID:37227036
Occludin Regulates HIV-1 Infection by Modulation of the Interferon Stimulated OAS Gene Family., PMID:37209263
Differences in gene regulation by TLR3 and IPS-1 signaling in murine corneal epithelial cells., PMID:37193897
Evaluating glioblastoma tumour sphere growth and migration in interaction with astrocytes using 3D collagen-hyaluronic acid hydrogels., PMID:37159233
Effects of Betulinic Acid on the Proliferation, Cellular Senescence, and Type 1 Interferon-Related Signaling Pathways in Human Dermal Fibroblasts., PMID:37116884
Coxsackievirus A6 Infection Causes Neurogenic Pathogenesis in a Neonatal Murine Model., PMID:36851724
Redox Regulation of m 6 A Methyltransferase METTL3 in Human β-cells Controls the Innate Immune Response in Type 1 Diabetes., PMID:36824909
Folate metabolism negatively regulates OAS-mediated antiviral innate immunity via ADAR3/endogenous dsRNA pathway., PMID:36822494
Occludin regulates HIV-1 infection by modulation of the interferon stimulated OAS gene family., PMID:36778388
piR-36249 and DHX36 together inhibit testicular cancer cells progression by upregulating OAS2., PMID:36710986
Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages., PMID:36678402
For research use only. Not for human or drug use.
