Catalog No.
YHD84301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val1193-Asn1393
Predicted molecular weight
25.08 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29475
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Constitutive NOS, Neuronal NOS, nNOS, N-NOS, bNOS, NOS type I, NC-NOS, Peptidyl-cysteine S-nitrosylase NOS1, NOS1, Nitric oxide synthase, brain
Dizocilpine Does Not Alter NOS1AP Gene Expression in Rats and in Cell Cultures., PMID:40508138
Selective Vulnerability of Hippocampi for Nitric Oxide Synthases in Alzheimer's Disease Pathology and Cognitive Abilities., PMID:40504299
A cell-type-specific epigenetic mechanism encodes social investigatory behavior via Lrhcn1 and Hcn1., PMID:40465726
Mechanism Underlying Hyperbaric Oxygen's Effect on Nitric Oxide in an in Vitro Model of Traumatic Brain Injury., PMID:40415360
Impact of temporal food restriction on sleep behavior and physiology of redheaded bunting., PMID:40389169
Synergistic Network Pharmacology: Preclinical Validation and Clinical Safety in Acute Ischemic Stroke., PMID:40371623
nNOS/NO in nucleus accumbens medicates NKCC1 in neonatal repetitive pain., PMID:40367902
Dissect Gender-Dependent Susceptibility SNPs in Progressive Osteoarthritis Using Regulator Motif Candidate of Genetic Association Strategy (RMCGA)., PMID:40362356
Truncated pyridinylbenzylamines: Potent, selective, and highly membrane permeable inhibitors of human neuronal nitric oxide synthase., PMID:40252563
Agmatine Enhances Dorsal Raphe Serotonergic Neuronal Activity via Dual Regulation of 5-HT1B and 5-HT2A Receptors., PMID:40243752
Nitric oxide synthase 1 inhibits the progression of esophageal cancer through interacting with nitric oxide synthase 1 adaptor protein., PMID:40235872
Exploring the Potential of Dolutegravir in Alzheimer's Disease Treatment: Insights from Network Pharmacology and In Silico Docking Studies., PMID:40231534
Distribution and Neurochemical Characterization of Dorsal Root Ganglia (DRG) Neurons Containing Phoenixin (PNX) and Supplying the Porcine Urinary Bladder., PMID:40214470
Astrocyte glucose-6-phosphatase-Beta regulates ventromedial hypothalamic nucleus glucose counterregulatory neurotransmission and systemic hormone profiles., PMID:40132240
Becker muscular dystrophy mice showed site-specific decay of type IIa fibers with capillary change in skeletal muscle., PMID:40094282
Metformin ablates high fat diet-induced skeletal muscle hypertrophy and elevation of sarcolemmal GLUT4 when feeding is initiated in young adult male mice., PMID:40052722
High-throughput screening identifies a novel small-molecule modulator of Hsp70 that selectively enhances ubiquitination and degradation of misfolded neuronal NO synthase., PMID:40023517
Ventromedial hypothalamic nucleus neuronal nitric oxide knockdown effects on GABAergic neuron metabolic sensor and transmitter marker gene expression in the male rat., PMID:39994513
Effect of Anti-TNF Monoclonal Antibody on Enteric Neurons and Enteric Glial Cells in Experimental Colitis., PMID:39946069
The impact of cytokines and tumour-conditioned medium on the properties of murine in vitro generated myeloid-derived suppressor cells., PMID:39865924
Islet NO-Synthases, extracellular NO and glucose-stimulated insulin secretion: Possible impact of neuronal NO-Synthase on the pentose phosphate pathway., PMID:39854399
Rh-relaxin-2 attenuates oxidative stress and neuronal apoptosis via ERK-nNOS-NO pathway after germinal matrix hemorrhage in rats., PMID:39815354
Mas-related gene C (MrgC) receptor activation induced inhibition of neurochemical alterations in the spinal dorsal horn and dorsal root ganglia in a rat model of bone cancer pain., PMID:39780572
S-Nitrosylation of Dexras1 Controls Post-Stroke Recovery via Regulation of Neuronal Excitability and Dendritic Remodeling., PMID:39749632
Involvement of γ-Aminobutyric Acid and N-methyl-D-aspartate Receptors in Diabetic Gastropathy in Rats: Possible Beneficial Effect of Prolonged Treatment with Insulin and Magnesium Supplement., PMID:39736941
Haploinsufficiency of PDE2A causes in mice increased exploratory behavior associated with upregulation of neural nitric oxide synthase in the striatum., PMID:39733958
Neuronal nitric oxide synthase activation by tadalafil protects neurological impairments in a zebrafish larva model of hyperammonemia., PMID:39710060
Mapping of functional erectogenic nerves on the rat prostate., PMID:39657061
A novel anti-epileptogenesis strategy of temporal lobe epilepsy based on nitric oxide donor., PMID:39653809
Effect of ICG fluorescence-assisted new nerve-sparing of robot-assisted radical prostatectomy on lower urinary tract symptoms., PMID:39651627
Preferential neurogenesis of nitrergic neurons in the myenteric plexus of the DSS-induced colitis mouse colon causes colonic dysmotility in colitis., PMID:39602133
Effect of Short-Term Restraint Stress on the Expression of Genes Associated with the Response to Oxidative Stress in the Hypothalamus of Hypertensive ISIAH and Normotensive WAG Rats., PMID:39594444
Downregulation of neuronal nitric oxide synthase (nNOS) within the paraventricular nucleus in Ins2Akita-type-1 diabetic mice contributes to sympatho-excitation., PMID:39521242
Application of the Linear Interaction Energy Method to Nitric Oxide Synthase Structure-Based Inhibitor Design., PMID:39509139
Exercise training ameliorates carbon tetrachloride-induced liver fibrosis and anxiety-like behaviors., PMID:39470596
Nitric oxide synthase system in the brain development of neonatal hypothyroid rats., PMID:39461663
The Protective Effect of the Supplementation with an Extract from Aronia melanocarpa L. Berries against Cadmium-Induced Changes of Chosen Biomarkers of Neurotoxicity in the Brain-A Study in a Rat Model of Current Lifetime Human Exposure to This Toxic Heavy Metal., PMID:39456671
Protective Effect of Protocatechuic Aldehyde on Cerebral Ischemia/Reperfusion Injury in Rats through Blood-Brain Barrier Protection., PMID:39455496
Medicinal Chemistry Insights in Neuronal Nitric Oxide Synthase Inhibitors Containing Nitrogen Heterocyclic Compounds: A Mini Review., PMID:39436922
Neurogenic-derived 6-nitrodopamine is the most potent endogenous modulator of the mouse urinary bladder relaxation., PMID:39427808
Exploring novel natural compound-based therapies for Duchenne muscular dystrophy management: insights from network pharmacology, QSAR modeling, molecular dynamics, and free energy calculations., PMID:39415830
Down regulation of the c-Fos/MAP kinase signaling pathway during learning memory processes coincides with low GnRH levels in aluminum chloride-induced Alzheimer's male rats., PMID:39412689
Endoplasmic reticulum stress and expression of nitric oxide synthases in heart failure with preserved and with reduced ejection fraction - pilot study., PMID:39360989
Mechanisms of GTN-induced migraine: Role of NOS isoforms, sGC and peroxynitrite in a migraine relevant mouse model., PMID:39314067
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson's disease., PMID:39303715
Interindividual Variation in Gut Nitrergic Neuron Density Is Regulated By GDNF Levels and ETV1., PMID:39299667
A Skeletal Muscle-Mediated Anticontractile Response on Vascular Tone: Unraveling the Lactate-AMPK-NOS1 Pathway in Femoral Arteries., PMID:39289003
Mesocorticolimbic and Cardiometabolic Diseases-Two Faces of the Same Coin?, PMID:39273628
Long-term GABA Supplementation Regulates Diabetic Gastroenteropathy through GABA Receptor/trypsin-1/PARs/Akt/COX-2 Axis., PMID:39196532
Effects of apelin on neonatal brain neurogenesis in L-NAME-induced maternal preeclampsia., PMID:39164321
For research use only. Not for human or drug use.
