Catalog No.
YHD83201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Glu138
Predicted molecular weight
18.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29373
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CRABP-II, Cellular retinoic acid-binding protein II, CRABP2, Cellular retinoic acid-binding protein 2
UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epithelia., PMID:40372430
Canagliflozin alleviates progestin resistance by suppressing RARβ/CRABP2 signaling in THRB knockout endometrial cancer cells., PMID:40371351
Effect of MiRNA 204-5P Mimics and Lipopolysaccharide-Induced Inflammation on Transcription Factor Levels, Cell Maintenance, and Retinoic Acid Signaling in Primary Limbal Epithelial Cells., PMID:40332443
Proteomic analysis reveals potential biomarker candidates in serous ovarian tumors - a preliminary study., PMID:40330446
Dual Role of CRABP2 in Colorectal Cancer: Oncogenesis via Nuclear RB1 and Cytoplasmic AFG3L2/SLC25A39 Axis, While Limiting Liver Metastasis through Cytoplasmic AFG3L2/PINK1/Parkin-Mediated Mitophagy., PMID:40305785
Targeting the Aryl Hydrocarbon Receptor to Attenuate IGF1R Signaling in Thyroid Eye Disease., PMID:40257057
The mediating mechanism of Oct4 in the process of cleft palate induced by 2, 3, 7, 8-tetrachlorodibenz-p-dioxin (TCDD) and all-trans retinoic acid., PMID:40194363
CRABP2 (Cellular Retinoic Acid Binding Protein 2D): A novel biomarker for the diagnosis and prognosis involved in immune infiltration of lung adenocarcinoma., PMID:39991584
Quantitative Proteome and Phosphoproteome Profiling across Three Cell Lines Revealed Potential Proteins Relevant to Nasopharyngeal Carcinoma Metastasis., PMID:39970938
The interplay between retinoic acid binding proteins and retinoic acid degrading enzymes in modulating retinoic acid concentrations., PMID:39870433
GRPR Drives Metastasis via CRABP2 and FNDC4 Pathways in Lung Adenocarcinoma., PMID:39768218
Cellular retinoic acid-binding proteins regulate germ cell proliferation and sex determination in zebrafish., PMID:39575928
Melittin promotes the proliferation of Schwann cells in hyperglycemic environment by up‑regulating the Crabp2/Wnt/β‑catenin signaling pathway., PMID:39450531
Structural requirements for the specific binding of CRABP2 to cyclin D3., PMID:39419021
Heterogeneous fibroblasts contribute to fibrotic scar formation after spinal cord injury in mice and monkeys., PMID:39060269
CRABP2 promotes cell migration and invasion by activating PI3K/AKT and MAPK signalling pathways via upregulating LAMB3 in prostate cancer., PMID:39038078
Screening (ant)agonistic activities of xenobiotics on the retinoic acid receptor alpha (RARα) using in vitro and in silico analysis., PMID:38997027
Alteration of Gene Expression in Pathological Keratinization of the Ocular Surface., PMID:38935029
Prognostic role of CRABP2 in lung cancer: a meta-analysis., PMID:38915108
Identification of cellular retinoic acid binding protein 2 (CRABP2) as downstream target of nuclear factor I/X (NFIX): implications for skeletal dysplasia syndromes., PMID:38827116
FOXD2-AS1 promotes malignant cell behavior in oral squamous cell carcinoma via the miR-378 g/CRABP2 axis., PMID:38807101
Overcoming retinoic acid resistance in HER2-enriched breast cancers: role of MYC., PMID:38708519
Mechanistic Study of CRABP2: Accelerating Lung Cancer Migration and Metastasis through Regulation of the ROS/Src Signaling Pathway., PMID:38607221
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion., PMID:38511490
CRABP2 reduces the sensitivity of Olaparib in ovarian cancer by downregulating Caspase-8 and decreasing the production of reactive oxygen species., PMID:38493911
Opposite Effects of CRABP1 and CRABP2 Homologs on Proliferation of Breast Cancer Cells and Their Sensitivity to Retinoic Acid., PMID:38462454
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes., PMID:38460933
CRABP2 affects chemotherapy resistance of ovarian cancer by regulating the expression of HIF1α., PMID:38195606
CRABP2 regulates infiltration of cancer-associated fibroblasts and immune response in melanoma., PMID:38186580
Cellular Retinoic Acid Binding Protein 2 (CRABP2), Up-regulated by HPV E6/E7, Leads to Aberrant Activation of the Integrin β1/FAK/ERK Signaling Pathway and Aggravates the Malignant Phenotypes of Cervical Cancer., PMID:38001389
The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer., PMID:37715025
Identification of key genes and biological pathways in lung adenocarcinoma by integrated bioinformatics analysis., PMID:37637684
A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function., PMID:37597518
Analysis on tumor immune microenvironment and construction of a prognosis model for immune-related skin cutaneous melanoma., PMID:37539569
Development of the semi-dry dot-blot method for intraoperative detecting micropapillary component in lung adenocarcinoma based on proteomics analysis., PMID:37016102
In-depth proteomics reveals the characteristic developmental profiles of early lung adenocarcinoma with epidermal growth factor receptor mutation., PMID:37004157
Network Pharmacology and Molecular Modeling to Elucidate the Potential Mechanism of Neem Oil against Acne vulgaris., PMID:36985821
The prognostic gene CRABP2 affects drug sensitivity by regulating docetaxel-induced apoptosis in breast invasive carcinoma: A pan-cancer analysis., PMID:36736488
CRABP2 Is Associated With Thyroid Cancer Recurrence and Promotes Invasion via the Integrin/FAK/AKT Pathway., PMID:36240291
Upregulation of CRABP2 by TET1-mediated DNA hydroxymethylation attenuates mitochondrial apoptosis and promotes oxaliplatin resistance in gastric cancer., PMID:36195596
CRABP2 - A novel biomarker for high-risk endometrial cancer., PMID:36163055
Preclinical insights into fucoidan as a nutraceutical compound against perfluorooctanoic acid-associated obesity via targeting endoplasmic reticulum stress., PMID:36034923
TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells., PMID:35831557
All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice., PMID:35764970
Biomarkers of Tretinoin Precursors and Tretinoin Efficacy in Patients With Moderate to Severe Facial Photodamage: A Randomized Clinical Trial., PMID:35675051
Krüppel-like transcription factor 16 transcriptional up-regulation of cellular retinoic acid-binding proteins-2 promotes the invasion and migration and inhibits apoptosis of retinoblastoma cells by regulating integrin-β1/focal adhesion kinase /extracellular signal-regulated kinase pathway., PMID:35671035
Consensus Gene Co-Expression Network Analysis Identifies Novel Genes Associated with Severity of Fibrotic Lung Disease., PMID:35628257
Exosome-related protein CRABP2 is upregulated in ovarian carcinoma and enhances cell proliferation., PMID:35578123
CRABPs Alter all-trans-Retinoic Acid Metabolism by CYP26A1 via Protein-Protein Interactions., PMID:35565751
CRABP2 accelerates epithelial mesenchymal transition in serous ovarian cancer cells by promoting TRIM16 methylation via upregulating EZH2 expression., PMID:35442568
For research use only. Not for human or drug use.
