Catalog No.
EHD82501
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Gln541
Predicted molecular weight
87.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29320
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HEK, Eph-like tyrosine kinase 1, EK4, EPHA3, Tyrosine-protein kinase receptor ETK1, Tyrosine-protein kinase TYRO4, Ephrin type-A receptor 3, hEK4, ETK, TYRO4, ETK1, Human embryo kinase, EPH-like kinase 4
Identification of regulatory cell death-related genes during MASH progression using bioinformatics analysis and machine learning strategies., PMID:40406118
Regulatory role of neuronal guidance proteins in spinal cord injury., PMID:40364635
Gene Expression Variations Induced by Sevoflurane in Glia and Glioma Cells and the Role of EPHA3 in Sevoflurane's Anti-Glioma Effect., PMID:39931981
Prediction of Lung Adenocarcinoma Driver Genes Through Protein-Protein Interaction Networks Utilizing GenePlexus., PMID:39696915
Altered TP53, CDKN2A, ATM, EPHA7, POT1, CHEK1, GRIN2A, and EGFR Predict Shorter Survival in Penile Squamous Cell Carcinoma., PMID:39694330
VIM-AS1, which is regulated by CpG methylation, cooperates with IGF2BP1 to inhibit tumor aggressiveness via EPHA3 degradation in hepatocellular carcinoma., PMID:39617786
EphA-Mediated Regulation of Stomatin Expression in Prostate Cancer Cells., PMID:39377541
Exploring Mitochondrial Autophagy Dysregulation in Osteosarcoma: Its Implications for Prognosis and Targeted Therapy., PMID:39297461
Clinicopathological characteristics and genetic features of young and senior Ewing sarcoma patients., PMID:39285408
Identification of potential diagnostic biomarkers and therapeutic targets in patients with hypoxia pulmonary hypertension., PMID:39226824
EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responses., PMID:39111833
EphA3 CAR T cells are effective against glioblastoma in preclinical models., PMID:39111832
A pan-cancer analysis of EphA family gene expression and its association with prognosis, tumor microenvironment, and therapeutic targets., PMID:38952552
Genetic mutation profiling reveals biomarkers for targeted therapy efficacy and prognosis in non-small cell lung cancer., PMID:38496877
Genetic architecture of the structural connectome., PMID:38438384
Features and Factors Associated With Myeloid Neoplasms After Chimeric Antigen Receptor T-Cell Therapy., PMID:38386311
Genetic alterations predict poor efficacy, outcomes and resistance to second-line osimertinib treatment in non-small cell lung cancer., PMID:38323283
Contrasting Effects of Cancer-Associated Mutations in EphA3 and EphB2 Kinases., PMID:38252844
Network pharmacology combines machine learning, molecular simulation dynamics and experimental validation to explore the mechanism of acetylbinankadsurin A in the treatment of liver fibrosis., PMID:38169205
Meta-analysis of microarray data to determine gene indicators involved in the cisplatin resistance in ovarian cancer., PMID:37937323
Reanalysis of EphA3 Knock-In Double Maps in Mouse Suggests That Stochasticity in Topographic Map Formation Acts at the Retina Rather than between Competing Mechanisms at the Colliculus., PMID:37852780
A BRCA2 germline mutation and high expression of immune checkpoints in a TNBC patient., PMID:37813891
In-silico and structure-based assessment to evaluate pathogenicity of missense mutations associated with non-small cell lung cancer identified in the Eph-ephrin class of proteins., PMID:37813626
Inhibition of EphA3 Expression in Tumour Stromal Cells Suppresses Tumour Growth and Progression., PMID:37760615
Differential effects of PTH (1-34), PTHrP (1-36) and abaloparatide on the murine osteoblast transcriptome., PMID:37645806
A combined immunopeptidomics, proteomics, and cell surface proteomics approach to identify immunotherapy targets for diffuse intrinsic pontine glioma., PMID:37637064
Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome., PMID:37587118
The Ephrin tyrosine kinase a3 (EphA3) is a novel mediator of RAGE-prompted motility of breast cancer cells., PMID:37434266
Crystal structure of the kinase domain of a receptor tyrosine kinase from a choanoflagellate, Monosiga brevicollis., PMID:37310965
A narrative review of the role of Eph receptors in head and neck squamous cell carcinoma., PMID:37279081
Knockdown of circ_CLIP2 regulates the proliferation, metastasis and apoptosis of glioma cells through miR-641/EPHA3/STAT3 axis., PMID:37129498
Circular RNA EPHA3 suppresses progression and metastasis in prostate cancer through the miR-513a-3p/BMP2 axis., PMID:37118847
Characterization of Histone Modifications in Late-Stage Rotator Cuff Tendinopathy., PMID:36833423
Eph Receptors in Cancer., PMID:36830852
Establishment of Bactrian Camel Induced Pluripotent Stem Cells and Prediction of Their Unique Pluripotency Genes., PMID:36768240
EPHA3 Could Be a Novel Prognosis Biomarker and Correlates with Immune Infiltrates in Bladder Cancer., PMID:36765579
Suppression of KSHV lytic replication and primary effusion lymphoma by selective RNF5 inhibition., PMID:36656913
May EPH/Ephrin Targeting Revolutionize Lung Cancer Treatment?, PMID:36613532
EphA3 targeted by miR-3666 contributes to melanoma malignancy via activating ERK1/2 and p38 MAPK pathways., PMID:36578556
Bioinformatic analysis of potential biomarkers and mechanisms of immune infiltration in mitral regurgitation complicated by atrial fibrillation., PMID:36467340
Molecular identity of proprioceptor subtypes innervating different muscle groups in mice., PMID:36369193
Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney., PMID:36266461
Temozolomide hexadecyl ester targeted plga nanoparticles for drug-resistant glioblastoma therapy via intranasal administration., PMID:36059989
In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes., PMID:36028553
Novel neoplasms associated with syndromic pediatric medulloblastoma: integrated pathway delineation for personalized therapy., PMID:35978432
Genomic features of Chinese small cell lung cancer., PMID:35596192
ADAM10-cleaved ephrin-A5 contributes to prostate cancer metastasis., PMID:35551177
The Hippo effector YAP1/TEAD1 regulates EPHA3 expression to control cell contact and motility., PMID:35264657
Artesunate-induced Cellular Effects Are Mediated by Specific EPH Receptors and Ephrin Ligands in Breast Carcinoma Cells., PMID:34949656
Two progressed malignant phyllodes tumors of the breast harbor alterations in genes frequently involved in other advanced cancers., PMID:34399808
For research use only. Not for human or drug use.
