Catalog No.
YHD77901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly21-Val142
Predicted molecular weight
16.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P28325
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CST5, Cystatin-5, Cystatin-D
Distinct proteomic signatures in Ethiopians predict acute and long-term sequelae of COVID-19., PMID:40475767
Proteomic Profiling of Nasal Fluids and Serum for Type 2 Nasal Polyps Diagnosis., PMID:40280274
Inflammatory Protein Signatures of Sepsis Risk and Mortality: A Mendelian Randomization Study., PMID:40267509
Deciphering genetic causality between plasma BDNF and 91 circulating inflammatory proteins through bidirectional mendelian randomization., PMID:40133606
From gut to kidney: microbiota modulates stone risk through inflammation-a mediated Mendelian randomization study., PMID:39718578
Causality Between 91 Circulating Inflammatory Proteins and Various Asthma Phenotypes: A Mendelian Randomization Study., PMID:39526130
Plasma proteomic signature of neonates in the context of placental histological chorioamnionitis., PMID:39237269
A Multiomic Analysis to Identify Drivers of Subclinical Vascular Disease in Systemic Lupus Erythematosus., PMID:38923259
Causal Relationships Between Circulating Inflammatory Proteins and Obstructive Sleep Apnea: A Bidirectional Mendelian Randomization Study., PMID:38894977
Diagnostic patterns of serum inflammatory protein markers in children with Lyme neuroborreliosis., PMID:38723400
Immune cell signatures and inflammatory mediators: unraveling their genetic impact on chronic kidney disease through Mendelian randomization., PMID:38703294
The Immune Signature of CSF in Multiple Sclerosis with and without Oligoclonal Bands: A Machine Learning Approach to Proximity Extension Assay Analysis., PMID:38203309
Associations of inflammation-related proteome with demographic and clinical characteristics of people with HIV in South Africa., PMID:37672793
STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion., PMID:36944334
Distinct inflammation-related proteins associated with T cell immune recovery during chronic HIV-1 infection., PMID:36408648
Inflammatory plasma proteins predict short-term mortality in patients with an acute myocardial infarction., PMID:36209229
Multiplex protein profiling of bronchial aspirates reveals disease-, mortality- and respiratory sequelae-associated signatures in critically ill patients with ARDS secondary to SARS-CoV-2 infection., PMID:35967328
Optimization of Microflow LC Coupled with Scanning SWATH and Its Application in Hepatocellular Carcinoma Tissues., PMID:35653712
Machine-Learning Analysis of Serum Proteomics in Neuropathic Pain after Nerve Injury in Breast Cancer Surgery Points at Chemokine Signaling via SIRT2 Regulation., PMID:35408848
Signal-mediated localization of Candida albicans pheromone response pathway components., PMID:33793759
Genome-wide estrogen receptor β chromatin binding in human colon cancer cells reveals its tumor suppressor activity., PMID:33754337
Secreted cystatins decrease proliferation and enhance apoptosis of human leukemic cells., PMID:32810913
Upregulation of circulating inflammatory biomarkers under the influence of periodontal disease in rheumatoid arthritis patients., PMID:32403006
Aberrant inflammatory profile in acute but not recovered anorexia nervosa., PMID:32389698
Long-Term Oral Administration of LLHK, LHK, and HK Alters Gene Expression Profile and Restores Age-Dependent Atrophy and Dysfunction of Rat Salivary Glands., PMID:32093221
Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers., PMID:31817800
Data-driven discovery of mid-pregnancy immune markers associated with maternal lifetime stress: results from an urban pre-birth cohort., PMID:31664889
Association between Biomarkers of Low-grade Inflammation and Sex Hormones in Women with Polycystic Ovary Syndrome., PMID:31461765
Up-regulated CST5 inhibits bone resorption and activation of osteoclasts in rat models of osteoporosis via suppression of the NF-κB pathway., PMID:31402549
Investigation of the clinical significance and prospective molecular mechanisms of cystatin genes in patients with hepatitis B virus‑related hepatocellular carcinoma., PMID:31115549
Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care., PMID:31017044
Zyxin as a potential cancer prognostic marker promotes the proliferation and metastasis of colorectal cancer cells., PMID:30697742
Apremilast for moderate hidradenitis suppurativa: no significant change in lesional skin inflammatory biomarkers., PMID:30451329
Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans., PMID:29255038
A Polymorphism within the Vitamin D Transporter Gene Predicts Outcome in Metastatic Colorectal Cancer Patients Treated with FOLFIRI/Bevacizumab or FOLFIRI/Cetuximab., PMID:29208668
Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge., PMID:28771594
Cystatin D (CST5): An ultra-early inflammatory biomarker of traumatic brain injury., PMID:28694499
A simple biomarker scoring matrix for early gastric cancer detection., PMID:27488579
Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression., PMID:26364852
p53 directly activates cystatin D/CST5 to mediate mesenchymal-epithelial transition: a possible link to tumor suppression by vitamin D3., PMID:26158294
Evolution of C, D and S-type cystatins in mammals: an extensive gene duplication in primates., PMID:25329717
Differential profiles of salivary proteins with affinity to Streptococcus mutans lipoteichoic acid in caries-free and caries-positive human subjects., PMID:24848678
Anti-proliferative activity of 25-hydroxyvitamin D3 in human prostate cells., PMID:24291609
Antigen-presenting cells in parotid glands contain cystatin D originating from acinar cells., PMID:23262319
Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D₃ analogues with a long side chain at C12 and short C17 side chains., PMID:22989379
Evolutionary reshaping of fungal mating pathway scaffold proteins., PMID:21249169
Utilization of the mating scaffold protein in the evolution of a new signal transduction pathway for biofilm development., PMID:21221248
The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling., PMID:20223287
Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells., PMID:19662683
Down-regulation of human extracellular cysteine protease inhibitors by the secreted staphylococcal cysteine proteases, staphopain A and B., PMID:17391065
For research use only. Not for human or drug use.
