Catalog No.
YHD77701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp169-Tyr417
Predicted molecular weight
31.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P28300
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Lysyl oxidase, LOX, Protein-lysine 6-oxidase
Defining CDK12 as a tumor suppressor and therapeutic target in mouse models of tubo-ovarian high-grade serous carcinoma., PMID:40504161
Z-Form Stabilization By The Zα Domain Of Adar1p150 Has Subtle Effects On A-To-I Editing., PMID:40502085
Mutation in soybean Lox-2 PLAT/LH2 domain through CRISPR/Cas9 reduces seed lipoxygenase activity: responsible for undesirable flavour., PMID:40498336
Multiple ways to promote adult grass carp (Ctenopharyngodon idella) muscle hypertrophy: Application of dietary myo-inositol., PMID:40487104
Sheng-Jiang Powder Alleviates Th17/Treg Immune Imbalance of Experimental Autoimmune Encephalomyelitis by Regulating the Fatty Acids Metabolism., PMID:40486123
Protective effect of Allium hookeri water extract and its main compound, Cycloalliin, on foam cell formation in THP-1-derived macrophages., PMID:40475061
l-Lactate Oxidase-Based Biosensor Enables Quasi-Calibration-Free Detection of l-Lactate in Sweat of Acidic to Neutral pH., PMID:40474682
Arteriolar degeneration and stiffness in cerebral amyloid angiopathy are linked to Aβ deposition and lysyl oxidase., PMID:40465757
Butein arrests the cell cycle and inhibits lipoxygenase-5 and hyaluronidase activities in skin carcinoma cells., PMID:40440994
Microwave Assisted Synthesis of Antioxidant Dihydro-Pyrazole Hybrids as Possible Lipoxygenase Inhibitors., PMID:40430396
Combined Analysis of Transcriptomes and Metabolomes Reveals That MeJA-Mediated Flavonoid Biosynthesis Is Crucial for Pigment Deposition in Naturally Colored Green Cotton Fibers., PMID:40428421
Bionanocomposite Four-Channel Biosensor for Rapid and Convenient Monitoring of Glucose, Lactate, Ethanol and Starch., PMID:40422375
Interaction of neuropilin-1 and hepatocyte growth factor/C-Met pathway in liver fibrosis progression in hepatocyte-specific NRP-1 knockout mice., PMID:40419692
Innate extracellular mouse Hsp70 inflammatory properties are mediated by the interaction of Siglec-E and LOX-1 receptors., PMID:40412547
Genome-wide identification and characterization of lipoxygenases gene family in Luffa aegyptiaca revealed downregulation of LOX genes under heat stress., PMID:40399351
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19., PMID:40397714
Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis., PMID:40396123
AMP-Activated Protein Kinase mediates the anti-inflammatory and antioxidant effects of Ceiba speciosa and Ceiba insignis in a rat model of ulcerative colitis., PMID:40389087
POSTN Silencing Ameliorates LL37-Induced Rosacea and Inhibits the JAK2/STAT3 and NF-κB Pathways., PMID:40387439
Therapeutic potential of (1 → 4)-linked glucuronoglucan from an edible brown mussel Perna indica: A promising candidate for anti-inflammatory and antidyslipidemic nutraceuticals., PMID:40382067
Lysyl oxidase mediates regeneration of chondrocytes and extracellular matrix in the construction of tissue-engineered cartilage in vitro., PMID:40369030
Solid/Liquid/Gas Three-Phase Interface Enzymatic Reaction-Based Lactate Biosensor with Simultaneously High Sensitivity and Wide Linear Range., PMID:40368837
Secreted Protein Acidic and Rich in Cysteine (SPARC) Induced by the Renin-Angiotensin System Causes Endothelial Inflammation in the Early Stages of Hypertensive Vascular Injury., PMID:40362650
Multifaceted Biological Activities of Culinary Herb and Spice Extracts: In Vitro and In Silico Simulation Insights into Inflammation-Related Targets., PMID:40361539
Cinnamon bark oil application and modified atmosphere packaging alleviates chilling injury, ethylene production and maintains antioxidant system in persimmons., PMID:40359793
A Comprehensive Review on the Advancements of Dual COX-2/5-LOX Inhibitors as Anti-Inflammatory Drugs., PMID:40346930
Modifications in FLAP's second cytosolic loop influence 5-LOX interaction, inhibitor binding, and leukotriene formation., PMID:40344218
Lactobacillus reuteri (Limosilactobacillus reuteri) TISTR 2736 Supplementation Attenuates Vascular Injury and Oxidative Stress in Rats Fed a High-Cholesterol Diet., PMID:40342212
Phytochemical analysis and neuroprotective potential of Achillea santolina L. fractions., PMID:40341236
Proteome Alterations in Cardiac Fibroblasts: Insights from Experimental Myocardial Infarction and Clinical Ischaemic Cardiomyopathy., PMID:40332511
New Insights into the French Paradox: Free Radical Scavenging by Resveratrol Yields Cardiovascular Protective Metabolites., PMID:40331971
Utilization of Safflower Oil Byproducts: Phenylpropanoid Amides of 5-Hydroxytryptamine (PAHA)-Enriched Extract as a Solution for Antioxidant and Inflammatory Pathway Modulation., PMID:40331757
Effects of micro- and nanoplastic exposure on macrophages: a review of molecular and cellular mechanisms., PMID:40323219
Phosphatidylinositol 3-Kinase Signaling Enhances Intestinal Crypt Epithelial Cell Recovery after Radiation., PMID:40316215
Multimodal evaluation of lipoxygenase-targeting NSAIDs using integrated in vitro, SAR, in silico, cytotoxicity towards MCF-7 cell line, DNA docking and MD simulation approaches., PMID:40316117
Eosinophils and pleural macrophages counter regulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway., PMID:40313934
Downregulation of Akt induces proximal tubule epithelial cell apoptosis via Foxo-1-BIM pathway in proteinuric states., PMID:40313745
Design and synthesis of novel 2-S-alkylated Quinazolinones as dual BRAFV600E and EGFR inhibitors in melanoma: Mechanistic insights from apoptosis and cell cycle modulation., PMID:40311244
Sex-dependent upregulation in oxylipins involved in inflammation resolution in the cerebellum of Niemann-Pick disease C1 mice., PMID:40306479
Novel chalcone candidates as potential in vitro and in vivo anti-inflammatory agents: Synthesis, in silico docking, multitarget bioevaluation and molecular dynamic simulation., PMID:40306188
The increased matrix stiffness caused by LOXL2 activates Piezo1 channels to promote the migration and invasion of cervical cancer cells., PMID:40304808
Transpulmonary LOX-1 Levels Are Predictive of Acute Respiratory Distress Syndrome After Cardiac Surgery: A Proof-of-Concept Study., PMID:40299349
OTUD7B controls oxLDL uptake by stabilizing Lox-1 in THP-1 and U937 cells., PMID:40294697
Unveiling the therapeutic role of Vibrio alginolyticus GH5 exopolysaccharide in Alzheimer's disease., PMID:40294669
Investigations of In Vitro Anti-Acetylcholinesterase, Anti-Diabetic, Anti-Inflammatory, and Anti-Cancer Efficacy of Garden Cress (Lepidium sativum Linn.) Seed Extracts, as Well as In Vivo Biochemical and Hematological Assays., PMID:40284441
Insects as Source of Nutraceuticals with Antioxidant, Antihypertensive, and Antidiabetic Properties: Focus on the Species Approved in Europe up to 2024., PMID:40282785
Responses of the Lipoxygenase Gene Family to Drought Stress in Broomcorn Millet (Panicum miliaceum L.)., PMID:40282328
Effects of burdock oligosaccharide preventing membrane lipid peroxidation in postharvest blueberry fruit., PMID:40271834
An Updated Review on the Anti-Inflammatory Potential of Phyllanthus Genus., PMID:40271556
Exploring the role of LOX family in glioma progression and immune modulation., PMID:40270974
For research use only. Not for human or drug use.
