Anti-KLHL11 Antibody (R4A86)

Catalog No.

RHN91902

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Applications

IF, IHC, WB

Recommended Dilution

Application	Dilution
IF	1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

KLHL11, Kelch-like protein 11

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NVR0

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A86

Note

For research use only.

Opsoclonus-myoclonus syndrome associated with anti Kelch-like protein-11 antibodies in a young female patient without cancer., PMID:33862421

Paraneoplastic cochleovestibulopathy: clinical presentations, oncological and serological associations., PMID:34285066

Eculizumab monotherapy for NMOSD: Data from PREVENT and its open-label extension., PMID:34498507

Long-term MRI changes in a patient with Kelch-like protein 11-associated paraneoplastic neurological syndrome., PMID:34561925

Characterisation of TRIM46 autoantibody-associated paraneoplastic neurological syndrome., PMID:34921120

Clinical Reasoning: A Dizzy Architect., PMID:35121670

Identification of Caveolae-Associated Protein 4 Autoantibodies as a Biomarker of Immune-Mediated Rippling Muscle Disease in Adults., PMID:35696196

Bilateral hearing loss preceding rhomboencephalitis - a hint for Kelch-like 11 syndrome., PMID:36112277

Validation of MATCH score: a predictive tool for identification of patients with kelch-like protein-11 autoantibodies., PMID:36150843

Characterization of cardiac bradyarrhythmia associated with LGI1-IgG autoimmune encephalitis., PMID:36304459

Autoimmune Encephalitis Misdiagnosis in Adults., PMID:36441519

Dual ankyrinG and subpial autoantibodies in a man with well-controlled HIV infection with steroid-responsive meningoencephalitis: A case report., PMID:36756346

Paraneoplastic Neurologic Disorders., PMID:36781586

Anti-kelchlike protein 11 antibody-associated encephalitis: Two case reports and review of the literature., PMID:36815561

Paraneoplastic Kelch-like protein 11 antibody-associated cerebellar and limbic encephalitis caused by metastatic "burned-out" seminoma - A scar(r)y phenomenon., PMID:36989702

Autoimmune Encephalitis Criteria in Clinical Practice., PMID:37124463

Stiff person spectrum disorder diagnosis, misdiagnosis, and suggested diagnostic criteria., PMID:37212351

Utility of Protein Microarrays for Detection of Classified and Novel Antibodies in Autoimmune Neurologic Disease., PMID:37550073

Identification of SKOR2 IgG as a novel biomarker of paraneoplastic neurologic syndrome., PMID:37795104

CDR2 and CDR2L line blot performance in PCA-1/anti-Yo paraneoplastic autoimmunity., PMID:37841252

KLHL11 antibody-associated autoimmune encephalomyelitis in a middle-aged female patient: a case report and literature review., PMID:37881832

Anti-Kelch-like protein 11 antibody encephalitis: a case report and literature review., PMID:37954647

Kelch-like Protein-11 Encephalitis Associated With Squamous Cell Carcinoma of Unknown Origin: A Case Report., PMID:37982047

Kelch-like Protein 11 (KLHL11) Antibodies in Children With Seizures of Undetermined Cause., PMID:38148071

Peripheral nervous system manifestations of MOG antibody associated disease., PMID:38234084

Overview of Paraneoplastic Autoantibody-Mediated Cognitive Impairment and Behavioral Changes: A Narrative Review., PMID:38322089

Neurological autoimmunity in patients with non-pulmonary neuroendocrine neoplasms: clinical manifestations and neural autoantibody profiles., PMID:38466015

Immune Checkpoint Inhibitor-Associated Kelch-Like Protein-11 IgG Brainstem Encephalitis., PMID:38484218

Pearls & Oy-sters: KLHL11 IgG Paraneoplastic-Associated Hearing Loss and Rhombencephalitis in a Woman With Metastatic Müllerian Tumor., PMID:38484225

Magnetic Resonance Imaging Characteristics of LGI1-Antibody and CASPR2-Antibody Encephalitis., PMID:38497971

Clinical and serological insights into paraneoplastic brachial amyotrophic diplegia., PMID:38772930

Seizure-Related Falls and Near Falls in LGI1-IgG Autoimmune Encephalitis., PMID:38938695

Autoimmune Movement Disorders., PMID:39088289

Long-term outcomes in antibody-negative autoimmune encephalitis: a retrospective study., PMID:39278895

Teaching Video NeuroImage: Perivascular Tumefactive Neurosarcoidosis of the Basal Ganglia., PMID:39284110

Comprehensive Analysis of Paraneoplastic Neurologic Syndrome and PNS-CARE Diagnostic Criteria in Clinical Practice., PMID:39321395

Autoimmune Encephalitis and Paraneoplastic Neurologic Syndromes: A Nationwide Study on Epidemiology and Antibody Testing Performance., PMID:39467237

Phenotypic and oncological insights in ANNA1 autoimmunity: Age stratification and biomarker analysis., PMID:39556523

Case report: The case report of ofatumumab, a fully human anti-CD20 monoclonal antibody, in the treatment of KLHL11 encephalitis., PMID:39575244

Autoimmune brainstem encephalitis: Clinical associations, outcomes, and proposed diagnostic criteria., PMID:39708293

Frequency, characteristics, and immunological accompaniments of ataxia in anti-NMDAR antibody-associated encephalitis., PMID:39735552

MOG antibody-associated disease epidemiology in Olmsted County, USA, and Martinique., PMID:39812824

Unraveling calcium dysregulation and autoimmunity in immune mediated rippling muscle disease., PMID:39819455

Clinical Manifestations and Treatment Responses in Pediatric Neurofascin 155-IgG4 Autoimmune Nodopathy., PMID:39823553

Autoimmune encephalitis: recovery, residual symptoms and predictors of long-term sequelae., PMID:39832911

High-Throughput Immunoassays for Cavin-4 IgG: A Diagnostic Tool for Immune-Mediated Rippling Muscle Disease., PMID:39957412

Paraneoplastic KLHL11 encephalitis presenting with progressive tinnitus, hearing loss and ataxia., PMID:39978939

Upper motor neuron-predominant motor neuron disease: a novel immunotherapy-responsive association of GAD65 autoimmunity., PMID:39998694

Exploring autoantigens in autoimmune limbic encephalitis using phage immunoprecipitation sequencing., PMID:40133514

The Clinical Trial Landscape in Autoimmune Encephalitis: Challenges and Opportunities., PMID:40146951

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