Catalog No.
RHN89403
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
ELISA, IF, IHC
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:10000, IF: 1:100-1:500, IHC: 1:200-1:1000 |
Target
Proline-rich AKT1 substrate 1, 40 kDa proline-rich AKT substrate, PRAS40, AKT1S1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q96B36
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4A66
Note
For research use only.
Neuroprotective role of a proline-rich Akt substrate in apoptotic neuronal cell death after stroke: relationships with nerve growth factor., PMID:14973226
Target validation in drug discovery., PMID:16988416
[Preparation and detection of phosphorylated PRAS40 (Ser183) polyclonal antibody]., PMID:19835147
Pathway-based identification of biomarkers for targeted therapeutics: personalized oncology with PI3K pathway inhibitors., PMID:20686178
Accelerated tumor growth mediated by sublytic levels of antibody-induced complement activation is associated with activation of the PI3K/AKT survival pathway., PMID:23833306
Down-regulation of phosphoglucose isomerase/autocrine motility factor enhances gensenoside Rh2 pharmacological action on leukemia KG1α cells., PMID:24606425
mTOR activity in AIDS-related diffuse large B-cell lymphoma., PMID:28192480
Quantitative proteomics profiling reveals activation of mTOR pathway in trastuzumab resistance., PMID:28507275
Akt and mTORC1 signaling as predictive biomarkers for the EGFR antibody nimotuzumab in glioblastoma., PMID:30129426
Bloom Syndrome Protein Activates AKT and PRAS40 in Prostate Cancer Cells., PMID:31210839
Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine., PMID:33212364
Targeting PRAS40: a novel therapeutic strategy for human diseases., PMID:33504218
PCR Array Technology in Biopsy Samples Identifies Up-Regulated mTOR Pathway Genes as Potential Rejection Biomarkers After Kidney Transplantation., PMID:33681239
Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells., PMID:35123066
For research use only. Not for human or drug use.
