Catalog No.
YHD75501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His21-Pro481
Predicted molecular weight
54.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P27824
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Major histocompatibility complex class I antigen-binding protein p88, IP90, CANX, p90, Calnexin
Hepatitis B virus core protein promotes liver cancer progression by stabilizing CANX and suppressing IRF7 transcription., PMID:40514420
Targeting CALR reduces energy metabolism of esophageal cancer cells and inhibits tumor‑associated fibroblast infiltration., PMID:40417915
ATP2A2 regulates STING1/MITA-driven signal transduction including selective autophagy., PMID:40265346
FAM134B-mediated ER-phagy alleviates alcohol-related liver fibrosis by reducing endoplasmic reticulum stress., PMID:40154686
Deleterious KOs in the HLA Class I Antigen Processing and Presentation Machinery Induce Distinct Changes in the Immunopeptidome., PMID:40113210
ADAR1-HNRNPL-Mediated CircCANX Decline Promotes Autophagy in Chronic Obstructive Pulmonary Disease., PMID:40091520
DNA methylation patterns contribute to changes of cellular differentiation pathways in leukocytes with LOY from patients with Alzheimer´s disease., PMID:39998604
Calnexin promotes glioblastoma progression by inducing protective mitophagy through the MEK/ERK/BNIP3 pathway., PMID:39990231
Increased intracellular stress responses and decreased KLF2 in adult patients with atopic dermatitis., PMID:39938773
The ER protein CANX (calnexin)-mediated autophagy protects against alzheimer disease., PMID:39813987
Design, synthesis and biological evaluation of bisnoralcohol derivatives as novel IRF4 inhibitors for the treatment of multiple myeloma., PMID:39788064
Endoplasmic reticulum stress in the salivary glands of patients with primary Sjögren's syndrome, associated Sjögren's syndrome, and non-Sjögren's sicca syndrome: a comparative analysis and the influence of chloroquine., PMID:39780265
The dual role of calnexin on malignant progression and tumor microenvironment in glioma., PMID:39730581
Reticulophagy and viral infection., PMID:39394962
Analysis of Sigma-1 Receptor Antagonist BD1047 Effect on Upregulating Proteins in HIV-1-Infected Macrophages Exposed to Cocaine Using Quantitative Proteomics., PMID:39335448
Proteome and Glycoproteome Analyses Reveal Regulation of Protein Glycosylation Site-Specific Occupancy and Lysosomal Hydrolase Maturation by N-Glycan-Dependent ER-Quality Control., PMID:39235835
Dihydroartemisinin inhibits ATP6 activity, reduces energy metabolism of hepatocellular carcinoma cells, promotes apoptosis and inhibits metastasis via CANX., PMID:39161338
Aβ1-42 stimulates an increase in autophagic activity through tunicamycin-induced endoplasmic reticulum stress in HTR-8/SVneo cells and late-onset pre-eclampsia., PMID:38777993
Porcine epidemic diarrhea virus E protein induces formation of stress granules and attenuates protein translation through activation of the PERK/eIF2α signaling pathway., PMID:38643723
Molecular strategies of the pygmy grasshopper Eucriotettix oculatus adapting to long-term heavy metal pollution., PMID:38599159
The role of differentially expressed genes and immune cell infiltration in the progression of nonalcoholic steatohepatitis (NASH) to hepatocellular carcinoma (HCC): a new exploration based on bioinformatics analysis., PMID:38319987
Connecting reticulophagy and neuronal NTRK2/TrkB signaling., PMID:37941410
Quantitative Proteomics Characterization of the Effect and Mechanism of Trichostatin A on the Hippocampus of Type II Diabetic Mice., PMID:37864628
Introducing Critical Genes in Response to Photodynamic Therapy: A Network Analysis., PMID:37744009
Proteomic Investigation of Differential Interactomes of Glypican 1 and a Putative Disease-Modifying Variant of Ataxia., PMID:37585105
Critical Evaluation of Transcripts and Long Noncoding RNA Expression Levels in Prostate Cancer Following Radical Prostatectomy., PMID:37463569
Deciphering the Clinical Significance and Kinase Functions of GSK3α in Colon Cancer by Proteomics and Phosphoproteomics., PMID:37031867
Integrated metabolomics and phosphoproteomics reveal the protective role of exosomes from human umbilical cord mesenchymal stem cells in naturally aging mouse livers., PMID:37004949
PON2 ameliorates Ang II-induced cardiomyocyte injury by targeting the CANX/NOX4 signaling pathway., PMID:36840500
A microarray data analysis investigating the pathogenesis and potential biomarkers of autophagy and ferroptosis in intervertebral disc degeneration., PMID:36685932
Comprehensive transcriptomics and proteomics analysis of Carassius auratus gills in response to Aeromonas hydrophila., PMID:36589261
An artificial neural network model based on autophagy-related genes in childhood systemic lupus erythematosus., PMID:36114579
[Bioinformatic analysis of differentially expressed proteins in the dorsal raphe nucleus of rats after continuous treatment with olanzapine]., PMID:36073222
Neutrophil Transcriptional Deregulation by the Periodontal Pathogen Fusobacterium nucleatum in Gastric Cancer: A Bioinformatic Study., PMID:36033825
TOLLIP-mediated autophagic degradation pathway links the VCP-TMEM63A-DERL1 signaling axis to triple-negative breast cancer progression., PMID:35920704
Comparative transcriptomic analysis reveals region-specific expression patterns in different beef cuts., PMID:35596128
RNA-Binding Proteins and Alternative Splicing Genes Are Coregulated in Human Retinal Endothelial Cells Treated with High Glucose., PMID:35308095
KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity., PMID:35266843
6-Hydroxydopamine Induces Neurodegeneration in Terminally Differentiated SH-SY5Y Neuroblastoma Cells via Enrichment of the Nucleosomal Degradation Pathway: a Global Proteomics Approach., PMID:35258800
Characterization of DNA methylation as well as mico-RNA expression and screening of epigenetic markers in adipogenesis., PMID:35168604
Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway., PMID:35130104
Interactome of human and SARS-CoV-2 proteins to identify human hub proteins associated with comorbidities., PMID:34655901
A Chaperone-Like Role for EBI3 in Collaboration With Calnexin Under Inflammatory Conditions., PMID:34603342
The multifaceted regulation of mitophagy by endogenous metabolites., PMID:34583624
Endoplasmic reticulum-unfolded protein response signalling is altered in severe eosinophilic and neutrophilic asthma., PMID:34510013
miR-148a-3p silences the CANX/MHC-I pathway and impairs CD8+ T cell-mediated immune attack in colorectal cancer., PMID:34324740
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants., PMID:34224022
Prognosis and Characterization of Immune Microenvironment in Acute Myeloid Leukemia Through Identification of an Autophagy-Related Signature., PMID:34135913
Circulating small extracellular vesicles increase after an acute bout of moderate-intensity exercise in pregnant compared to non-pregnant women., PMID:34135428
Dermatan Sulfate Is a Potential Regulator of IgH via Interactions With Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts., PMID:34113352
For research use only. Not for human or drug use.
