Catalog No.
YHD73601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro75-Thr312
Predicted molecular weight
29.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P27361
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Microtubule-associated protein 2 kinase, p44-MAPK, Extracellular signal-regulated kinase 1, ERK1, MAPK3, MAP kinase isoform p44, Mitogen-activated protein kinase 3, ERK-1, PRKM3, Insulin-stimulated MAP2 kinase, p44-ERK1, MAPK 3, MAP kinase 3, ERT2
Multifaceted computational insights of murrayacinine as dual inhibitors of CDK2 and MAPK3 to combat cervical cancer., PMID:40513148
Bioinformatics analysis of hub genes and oxidative stress-related pathways in odontogenic keratocysts., PMID:40505773
Deciphering mechanisms of GPCR compounds against tuberculosis through ferroptosis inhibition using high-throughput screening and network pharmacology analysis., PMID:40505323
CEBPB regulates ERK1/2 activity through SOS1 and contributes to ovarian cancer progression., PMID:40483367
Role of ERK1/2 and p38 Protein Kinases in Tumors: Biological Insights and Clinical Implications., PMID:40464498
Cbl-b inhibitor NX-1607 activates MAPK/ERK signaling pathway and enhances T-cell activation., PMID:40447319
Comparative Study of ERK1/2, Bcl2, and Sorcin with Clinicopathological Characteristics of Gastric carcinoma: Tubular Adenocarcinoma Vs Signet Ring Cell Carcinoma., PMID:40439369
Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury., PMID:40438398
Dihydroartemisinin Alleviates Ulcerative Colitis via Target Identification and Pathway Modulation: A Cyberpharmacology Approach., PMID:40433891
Pericarpium Trichosanthis Injection Protects Isoproterenol-Induced Acute Myocardial Ischemia via Suppressing Inflammatory Damage and Apoptosis Pathways., PMID:40427511
Proteomic surveys of the mouse heart unveil cardiovascular responses to nitric oxide/cGMP signaling deficiencies., PMID:40425728
Babaco Mosaic Virus (BabMV) Induces Genome-Wide Transcriptomic Reprogramming in Carica papaya., PMID:40425527
Identification of TRPV1-Inhibitory Peptides from Takifugu fasciatus Skin Hydrolysate and Their Skin-Soothing Mechanisms., PMID:40422786
[Tiaozhou Ziyin recipe for treatment of premature ovarian insufficiency: efficacy, safety and mechanism]., PMID:40415424
Identification of Hub Genes and Pathways Associated with Ageing in Diabetic Encephalopathy Based on Transcriptome Analysis., PMID:40397335
TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts., PMID:40383937
Network toxicological and single-cell sequencing reveals the potential mechanisms of psoriatic toxicity of polybrominated diphenyl ethers., PMID:40367614
Network pharmacology study on the mechanism of Curcumae Rhizoma in the treatment of non-small cell lung cancer., PMID:40355237
Gan-tang-yi decoction improves hepatic insulin resistance through activation of IRS2/PI3K/Akt pathway and inhibition of AGEs/RAGE pathway in cirrhotic rats., PMID:40345270
Study on the mechanism of Xanthoceras sorbifolia Bunge oil in the treatment of Alzheimer's disease by an integrated "network pharmacology-metabolomics" strategy., PMID:40340504
Study on the role and function of RRS1 in cutaneous squamous cell carcinoma., PMID:40339202
Exosomes derived from human umbilical cord mesenchymal stem cells can reverse ventricular remodeling and improve long-term cardiac function after acute myocardial infarction., PMID:40327908
Ganoderic acid A: an in-depth review of pharmacological effects and molecular docking analysis., PMID:40316150
A neuroimmune pathway drives bacterial infection., PMID:40315317
The phosphorylation of Pak1 by Erk1/2 to drive cell migration requires Arl4D acting as a scaffolding protein., PMID:40309925
Nucleus Accumbens Proteome Disbalance in an Adolescent Mouse Model of Schizophrenia and Nicotine Misuse Comorbidity., PMID:40299488
Integrated multi-omics insight into the molecular networks of oxidative stress in triggering multiple sclerosis., PMID:40280189
Assessing the neurotoxic risks of triethyl citrate in daily environmental exposure using network toxicology and molecular docking., PMID:40273610
Activation of the ERK1/2 Molecular Pathways and Its Relation to the Pathogenicity of Human Malignant Tumors., PMID:40264578
Network Pharmacology and Experimental Validation of the Effects of Shenling Baizhu San, Quzhi Ruangan Fang and Gexia Zhuyu Tang on the Intestinal Flora of Rats with NAFLD., PMID:40260263
Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmacology, molecular docking and molecular dynamics simulations., PMID:40248103
Unraveling the Role of NeuroD2 in Ischemic Pathophysiology: Insight into Neuroprotection Mechanisms Associated with AKT Survival Kinase., PMID:40237843
Potential Anti-inflammatory Properties of Corydalis rhizoma for Co-Treatment of Neuropathic Pain and Major Depressive Disorder: Network Pharmacology with Molecular Docking and Molecular Dynamics Simulation Approaches., PMID:40231535
Exploring the Potential of Dolutegravir in Alzheimer's Disease Treatment: Insights from Network Pharmacology and In Silico Docking Studies., PMID:40231534
Aripiprazole alleviates the high prolactin levels induced by amisulpride via distinct molecular mechanisms: a network pharmacology and molecular docking study., PMID:40229786
An integrative study on the effects of Lingguizhugan decoction in treating Alzheimer's disease rats through modulation of multiple pathways involving various components., PMID:40228446
Ethyl caffeate alleviates inflammatory response and promotes recovery in septic-acute lung injury via the TNF-α/NF-κB/MMP9 Axis., PMID:40220405
Neuroprotective effects of Centella asiatica against LPS/amyloid beta-induced neurodegeneration through inhibition of neuroinflammation., PMID:40204151
Evaluating the Mechanism Underlying Multi-Compound Synergy of Banxia Decoction in the Treatment of Hashimoto's Thyroiditis Based on Network Pharmacology and Molecular Docking., PMID:40196382
Investigation of Tongqiao Huashuan Granules' effect on hippocampal neuron autophagy in vascular dementia rats via the PI3K/Akt-mTOR signaling pathway using network pharmacology and experimental validation., PMID:40191596
Understanding metabolic characteristics and molecular mechanisms of large to giant congenital melanocytic nevi: implications for melanoma risk and therapeutic targets., PMID:40190193
Gene expression analysis in circulating tumour cells to determine resistance to CDK4/6 inhibitors plus endocrine therapy in HR + /HER2- metastatic breast cancer patients., PMID:40186268
Exploring the mechanism of Pujin oral liquid in the treatment of preterm white matter injury using network pharmacology and molecular docking., PMID:40184095
LINC00665/miR-132-5p Reduces Inflammation in Epileptic Cells by Targeting MAPK3., PMID:40183143
Network pharmacology and in silico analysis reveal Kochiae Fructus as a potential therapeutic against atopic dermatitis through immunomodulatory pathway interactions., PMID:40179089
Trigonella foenum-graecum L. protects against renal function decline in a mouse model of type 2 diabetic nephropathy by modulating the PI3K-Akt-ERK signaling pathway., PMID:40170727
Exploring Mechanisms of Ephx2 in Treating Atherosclerosis Using Independent Cascade Model and Adverse Outcome Pathways., PMID:40151075
Identification of Candidate Lung Function-Related Plasma Proteins to Pinpoint Drug Targets for Common Pulmonary Diseases: A Comprehensive Multi-Omics Integration Analysis., PMID:40136421
Network pharmacology-based investigation of the pharmacological mechanisms of diosgenin in nonalcoholic steatohepatitis., PMID:40133701
Galangin ameliorates PTU-induced vitiligo in zebrafish and B16F10 cells by increasing melanogenesis through activation of the p38/JNK MAPK pathway., PMID:40129935
For research use only. Not for human or drug use.
