Catalog No.
YHD72601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr120-Leu358
Predicted molecular weight
28.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26992
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ciliary neurotrophic factor receptor subunit alpha, CNTFR, CNTF receptor subunit alpha, CNTFR-alpha
The potential of ciliary neurotrophic factor receptor as a biomarker for urine-based noninvasive diagnosis of prostate cancer., PMID:40493768
Patient-derived Induced Pluripotent Stem Cells as a Model to Study Frontotemporal Dementia Pathologies., PMID:39764003
Acute responses of strength-related gene expressions to maximum strength and force sense acuity., PMID:38812641
Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR., PMID:38569939
Immuno-oncologic signature of malignant transformation in oral squamous cell carcinoma., PMID:37739913
CLCF1 signaling restrains thermogenesis and disrupts metabolic homeostasis by inhibiting mitochondrial biogenesis in brown adipocytes., PMID:37549287
Transcription factor TP63 mediates LncRNA CNTFR-AS1 to promote DNA damage induced by neodymium oxide nanoparticles via homologous recombination repair., PMID:37451587
MiR-708 regulates the biological behavior of childhood leukemia cells by binding to the 3'utr end of the target gene and reducing the level of the target gene., PMID:37224029
Ciliary neurotrophic factor is increased in the plasma of patients with obesity and its levels correlate with diabetes and inflammation indices., PMID:35585213
The role of neurotrophin genes involved in the vulnerability to gambling disorder., PMID:35484167
The Molecular Structure and Role of Humanin in Neural and Skeletal Diseases, and in Tissue Regeneration., PMID:35372353
Preoperative Serum Calcitonin Level and Ultrasonographic Characteristics Predict the Risk of Metastatic Medullary Thyroid Carcinoma: Functional Analysis of Calcitonin-Related Genes., PMID:35280443
RNA-Seq analysis reveals sex-dependent transcriptomic profiles of human subacromial bursa stratified by tear etiology., PMID:35266580
Decreased Expression of Glial-Derived Neurotrophic Factor Receptors in Glaucomatous Human Retinas., PMID:34738835
miR-21a-5p Promotes Inflammation following Traumatic Spinal Cord Injury through Upregulation of Neurotoxic Reactive Astrocyte (A1) Polarization by Inhibiting the CNTF/STAT3/Nkrf Pathway., PMID:34345208
Three new cases of Crisponi /cold induced sweating syndrome (CS/CISS1) in Turkish families., PMID:33910095
Primary hypothyroidism and autoimmune thyroiditis alter the transcriptional activity of genes regulating neurogenesis in the blood of patients., PMID:33600668
The IL-27 component EBI-3 and its receptor subunit IL-27Rα are essential for the cytoprotective action of humanin on male germ cells†., PMID:33330922
Ciliary Neurotrophic Factor Receptor rs41274853 Polymorphism Is Associated With Weightlifting Performance in Japanese Weightlifters., PMID:33105352
Humanin: A mitochondria-derived peptide with emerging properties., PMID:32800320
Engineering a potent receptor superagonist or antagonist from a novel IL-6 family cytokine ligand., PMID:32522868
Identification of Long Noncoding RNAs as Predictors of Survival in Triple-Negative Breast Cancer Based on Network Analysis., PMID:32190687
Identification of core biomarkers associated with pathogenesis and prognostic outcomes of laryngeal squamous-cell cancer using bioinformatics analysis., PMID:32067095
Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma., PMID:31700175
microRNA-146a Promotes Growth of Acute Leukemia Cells by Downregulating Ciliary Neurotrophic Factor Receptor and Activating JAK2/STAT3 Signaling., PMID:31538427
Crisponi/cold-induced sweating syndrome: Differential diagnosis, pathogenesis and treatment concepts., PMID:31497877
Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., PMID:30578761
Ciliary Neurotrophic Factor (CNTF) Protects Myocardial Cells from Oxygen Glucose Deprivation (OGD)/Re-Oxygenation via Activation of Akt-Nrf2 Signaling., PMID:30504707
Quantitative Assessment of Sialo-Glycoproteins and N-Glycans during Cardiomyogenic Differentiation of Human Induced Pluripotent Stem Cells., PMID:28509371
miR-17-92 facilitates neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions., PMID:27567678
Red pitaya juice supplementation ameliorates energy balance homeostasis by modulating obesity-related genes in high-carbohydrate, high-fat diet-induced metabolic syndrome rats., PMID:27456968
RNA-Seq reveals 10 novel promising candidate genes affecting milk protein concentration in the Chinese Holstein population., PMID:27254118
Corneal alterations in Crisponi/CISS1 syndrome: A slit-lamp biomicroscopy and in vivo confocal microscopy corneal report., PMID:27054527
Transcriptome adaptation of the bovine mammary gland to diets rich in unsaturated fatty acids shows greater impact of linseed oil over safflower oil on gene expression and metabolic pathways., PMID:26861594
CNTFR Genotype and Sprint/power Performance: Case-control Association and Functional Studies., PMID:26837930
Neurotrophin signaling in a genitofemoral nerve target organ during testicular descent in mice., PMID:26718832
Cardiotrophin-like cytokine factor 1 (CLCF1) and neuropoietin (NP) signalling and their roles in development, adulthood, cancer and degenerative disorders., PMID:26198769
Ciliary neurotrophic factor (CNTF): New facets of an old molecule for treating neurodegenerative and metabolic syndrome pathologies., PMID:26187860
Angiogenic, neurotrophic, and inflammatory system SNPs moderate the association between birth weight and ADHD symptom severity., PMID:25346392
The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR)., PMID:24802752
Family-based association study of ciliary neurotrophic factor receptor and norepinephrine transporter genes in attention-deficit hyperactivity disorder., PMID:24565995
Expanding the mutational spectrum of CRLF1 in Crisponi/CISS1 syndrome., PMID:24488861
High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets., PMID:24034256
Overexpression of miR-708 and its targets in the childhood common precursor B-cell ALL., PMID:23970374
Expression of interleukin-6 family receptors in NK92 cells is regulated by cytokines and not through direct interaction with Plasmodium falciparum-infected erythrocytes., PMID:23398366
The cytokines cardiotrophin-like cytokine/cytokine-like factor-1 (CLC/CLF) and ciliary neurotrophic factor (CNTF) differ in their receptor specificities., PMID:22986012
Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL-6 in non-small cell lung cancer in vivo., PMID:22962265
The anorectic effect of CNTF does not require action in leptin-responsive neurons., PMID:22518062
Cytokine-like factor 1 gene expression is enriched in idiopathic pulmonary fibrosis and drives the accumulation of CD4+ T cells in murine lungs: evidence for an antifibrotic role in bleomycin injury., PMID:22429962
Regulation of neurokine receptor signaling and trafficking., PMID:22306348
For research use only. Not for human or drug use.
