Catalog No.
RHK05401
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Applications
ELISA, FCM
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:10000, FCM: 1:200-1:400 |
Target
Bcl-2-like protein 2, BCL2L2, Bcl2-L-2, KIAA0271, Apoptosis regulator Bcl-W, BCLW
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92843
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Y30
Note
For research use only.
Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis., PMID:10809232
Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine., PMID:10951589
Tissue expression and subcellular localization of the pro-survival molecule Bcl-w., PMID:11423909
Essential role for the BH3-only protein Bim but redundant roles for Bax, Bcl-2, and Bcl-w in the control of granulocyte survival., PMID:12433687
Role of E-selectin in cell apoptosis induced by allogeneic blood perfusion in isolated mouse lung., PMID:16177643
Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma., PMID:17210792
Follicle-stimulating hormone affects spermatogonial survival by regulating the intrinsic apoptotic pathway in adult rats., PMID:18094353
Cartilage polysaccharide induces apoptotic cell death of L1210 cells., PMID:19431040
Evidence that inhibition of BAX activation by BCL-2 involves its tight and preferential interaction with the BH3 domain of BAX., PMID:21060336
Bonafide Targets of Deregulated microRNAs in Non-Small Cell Lung Cancer as Tool to Identify Novel Therapeutic Targets: A Review., PMID:27719642
BCL-W is a regulator of microtubule inhibitor-induced mitotic cell death., PMID:27231850
Inhibition of neurotensin receptor 1 induces intrinsic apoptosis via let-7a-3p/Bcl-w axis in glioblastoma., PMID:28494471
Cyramza induces apoptosis of HCC4006 cell by affecting the level of Bcl-w., PMID:28742199