Catalog No.
EHD70601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ile265
Predicted molecular weight
29.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P26436
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ACRV1, Acrosomal vesicle protein 1, Acrosomal protein SP-10
Synaptotagmin 13 Could Drive the Progression of Esophageal Squamous Cell Carcinoma Through Upregulating ACRV1., PMID:39046915
Generation and Characterization of a Transgenic Mouse That Specifically Expresses the Cre Recombinase in Spermatids., PMID:37239343
Differential Proteomic Analysis of Human Sperm: A Systematic Review to Identify Candidate Targets to Monitor Sperm Quality., PMID:37118964
Germ Cell-Specific Proteins AKAP4 and ASPX Facilitate Identification of Rare Spermatozoa in Non-Obstructive Azoospermia., PMID:37087050
Momelotinib (JAK1/JAK2/ACVR1 inhibitor): mechanism of action, clinical trial reports, and therapeutic prospects beyond myelofibrosis., PMID:36861402
Acrosomal vesicle protein in predicting progression of pancreatitis in Chinese patients with acute pancreatitis., PMID:36861244
Transcriptional regulation of spatiotemporal gene expression within the seminiferous epithelium: Mouse Acrv1 gene as a model., PMID:36793255
Combination of high-fat diet and cadmium impairs testicular spermatogenesis in an m6A-YTHDF2-dependent manner., PMID:36084736
Recellularized rat testis scaffolds with embryoid bodies cells: a promising approach for tissue engineering., PMID:35086406
Hypomorphic and hypermorphic mouse models of Fsip2 indicate its dosage-dependent roles in sperm tail and acrosome formation., PMID:34125190
The Germ Cell-Specific Markers ZPBP2 and PGK2 in Testicular Biopsies Can Predict the Presence as well as the Quality of Sperm in Non-obstructive Azoospermia Patients., PMID:33507524
Acrosomal marker SP-10 (gene name Acrv1) for staging of the cycle of seminiferous epithelium in the stallion., PMID:32758798
A 50-bp enhancer of the mouse acrosomal vesicle protein 1 gene activates round spermatid-specific transcription in vivo†., PMID:31290539
p21WAF1/Cip1 Regulation by hYSK1 Activates SP-1 Transcription Factor and Increases MMP-2 Expression under Hypoxic Conditions., PMID:30646538
Immunolocalization of TAR DNA-binding protein of 43 kDa (TDP-43) in mouse seminiferous epithelium., PMID:28600885
Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System., PMID:28398669
Transcription and Splicing Factor TDP-43: Role in Regulation of Gene Expression in Testis., PMID:28278534
Seminal biomarkers for the evaluation of male infertility., PMID:26975492
Acrosome markers of human sperm., PMID:26748928
Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS., PMID:26408346
The acrosomal protein SP-10 (Acrv1) is an ideal marker for staging of the cycle of seminiferous epithelium in the mouse., PMID:25158006
Evaluation of efficacy and safety of recombinant sperm-specific contraceptive vaccine in albino mice., PMID:23405955
Generation of a conditional mouse model to target Acvr1b disruption in adult tissues., PMID:23109354
Involvement of the prostate and testis expression (PATE)-like proteins in sperm-oocyte interaction., PMID:22402205
Members of the murine Pate family are predominantly expressed in the epididymis in a segment-specific fashion and regulated by androgens and other testicular factors., PMID:21942998
Developmental expression of ACRV1 in humans and mice., PMID:21488928
TDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo., PMID:21252238
Assessment of goat semen freezability according to the spermatozoa characteristics from fresh and frozen samples., PMID:18479850
The mouse sperm proteome characterized via IPG strip prefractionation and LC-MS/MS identification., PMID:18340633
Role of an insulator in testis-specific gene transcription., PMID:18184912
Sexual selection and the adaptive evolution of mammalian ejaculate proteins., PMID:18032407
NF45 and NF90 in murine seminiferous epithelium: potential role in SP-10 gene transcription., PMID:17942973
A novel CpG-free vertebrate insulator silences the testis-specific SP-10 gene in somatic tissues: role for TDP-43 in insulator function., PMID:17932037
Immunogenicity of a multi-component recombinant human acrosomal protein vaccine in female Macaca fascicularis., PMID:17643494
Human sperm protein encyclopedia and alloantigen index: mining novel allo-antigens using sera from ASA-positive infertile patients and vasectomized men., PMID:17548113
cis-requirement for the maintenance of round spermatid-specific transcription., PMID:16730344
Spermatid-specific promoter of the SP-10 gene functions as an insulator in somatic cells., PMID:14512027
Transcriptional regulation of spermiogenesis: insights from the study of the gene encoding the acrosomal protein SP-10., PMID:11730901
A monoclonal antibody to human SP-10 inhibits in vitro the binding of human sperm to hamster oolemma but not to human Zona pellucida., PMID:10775167
Round spermatid-specific transcription of the mouse SP-10 gene is mediated by a 294-base pair proximal promoter., PMID:10529272
Flow cytometric method to isolate round spermatids from mouse testis., PMID:10099985
Immunological response in the primate oviduct to a defined recombinant sperm immunogen., PMID:9421797
Oviductal antibody response to a defined recombinant sperm antigen in macques., PMID:9369161
An antigenically related polypeptide family is a major structural constituent of a stable acrosomal matrix assembly in bovine spermatozoa., PMID:9241046
Refinement of the differentiated phenotype of the spermatogenic cell line GC-2spd(ts)., PMID:8879510
Effect of immunization with human SP-10 in male rodents., PMID:8874713
Ly-6-domain proteins--new insights and new members: a C-terminal Ly-6 domain in sperm acrosomal protein SP-10., PMID:8883295
Inhibition of bovine fertilization in vitro by antibodies to SP-10., PMID:8882296
Complementary deoxyribonucleic acid cloning and characterization of mSP-10: the mouse homologue of human acrosomal protein SP-10., PMID:8547483
Oral immunization with attenuated Salmonella expressing human sperm antigen induces antibodies in serum and the reproductive tract., PMID:7492701
For research use only. Not for human or drug use.
