Catalog No.
YHD69001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys67-Glu302
Predicted molecular weight
28.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25963
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NFKBI, Major histocompatibility complex enhancer-binding protein MAD3, IkB-alpha, IkappaBalpha, I-kappa-B-alpha, IKBA, NF-kappa-B inhibitor alpha, NFKBIA, MAD3
tRF16 affects NFKBIA stability and promotes osteoarthritis progression by regulating ALKBH5 expression in m6A-dependent manner., PMID:40473927
In Vitro Anticancer Activity of Phytol on Human Non-Small Cell Lung Cancer A549 Cells., PMID:40468754
Sanguinoderma rugosum (Agaricomycetes), a Wild Malaysian Medicinal Mushroom, Triggers Anti-Neuroinflammatory Genes Expression in LPS-Stimulated BV-2 Microglial Cells., PMID:40460400
Identification of hub immune-related genes and construction of predictive models for systemic lupus erythematosus by bioinformatics combined with machine learning., PMID:40438384
Network pharmacology, prognostic analysis and experimental validation elucidate the therapeutic mechanism of Dingxiang Guanshitong in esophageal cancer., PMID:40436970
Identification of Hub Genes and Pathways Associated with Ageing in Diabetic Encephalopathy Based on Transcriptome Analysis., PMID:40397335
Fucoxanthin ameliorates Propionibacterium acnes-induced ear inflammation in mice by modulating the IκBα/NF-κB signaling pathway and inhibiting NF-κB nuclear translocation., PMID:40333903
Mechanistic Insights into Radiation Resistance in Colorectal Cancer: Gene Exploration Study., PMID:40332515
Utilizing bioinformatics to identify biomarkers and analyze their expression in relation to immune cell ratios in femoral head necrosis., PMID:40308566
Immune-related genetic single-nucleotide polymorphisms contribute to prognosis and response to chemotherapy in patients with acute lymphoblastic leukemia., PMID:40299016
Ru(II)-thymine complex suppresses acute myeloid leukemia stem cells by inhibiting NF-κB signaling., PMID:40288174
Leveraging Diverse Cell-Death Patterns to Decipher the Interactive Relation of Unfavorable Outcome and Tumor Microenvironment in Breast Cancer., PMID:40281780
Haemonchus contortus parasitic stages development and host immune responses in lambs of different sheep breeds., PMID:40273838
Bioinformatics analysis of oxidative phosphorylation-related differentially expressed genes in osteoporosis., PMID:40241169
Pulsed Radiofrequency Alleviates Acute Soft Tissue Injury in Rats by Regulating the TNF/mTOR Signaling Pathway., PMID:40197902
Comprehensive investigation into the discrete toxicity of curcumin on β-cell viability and insulin secretion., PMID:40185300
Study on mechanism of iridoid glycosides derivatives from Fructus Gardeniae in treatment of hepatic encephalopathy by network pharmacology and molecular docking technology., PMID:40184133
Identifying microglia-derived NFKBIA as a potential contributor to the pathogenesis of Alzheimer's disease and age-related macular degeneration., PMID:40105475
Integrated bioinformatics and validation reveal TMEM45A in systemic lupus erythematosus regulating atrial fibrosis in atrial fibrillation., PMID:40102753
Transcriptomic profiling identifies ferroptosis and NF-κB signaling involved in α-dimorphecolic acid regulation of microglial inflammation., PMID:40038710
Involvement of microRNA-146a-5p, but not -155-5p and -29b-5p, in left ventricular remodeling and dysfunction in spontaneously hypertensive rats., PMID:40033926
Genetic Comparison and Selection of Reproductive and Growth-Related Traits in Qinchuan Cattle and Two Belgian Cattle Breeds., PMID:40003088
Single-cell RNA sequencing of circulating immune cells supports inhibition of TNFAIP3 and NFKBIA translation as psoriatic arthritis biomarkers., PMID:39991156
uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease., PMID:39920690
Impact of modulating leptin sensitivity on the transcriptomic profile of adult-derived hypothalamic mouse neurons., PMID:39916981
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer's disease., PMID:39905093
Insulin Resistance Mediates the Association Between Vitamin D and Non-Alcoholic Fatty Liver Disease., PMID:39867257
Transcriptomic Profiling Reveals 17β-Estradiol Treatment Represses Ubiquitin-Proteasomal Mediators in Skeletal Muscle of Ovariectomized Mice., PMID:39865408
Exosomal NEDD4L derived from HG+oxLDL-induced vascular endothelial cells accelerates macrophage M1 polarization and oxLDL uptake by ubiquitinating IκBα and PPARγ., PMID:39775116
Identifying Biomarkers for Atherosclerosis via Gene Expression and Biological Networking., PMID:39773060
Immunomodulatory Effects of SPHK1 and Its Interaction with TFAP2A in Yellow Drum (Nibea albiflora)., PMID:39769404
Network pharmacology, molecular docking, and experimental verification reveal the mechanism of Yi-Shen-Hua-Shi granules treating acute kidney injury., PMID:39755185
Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival., PMID:39744815
Protective effects of Mycobacterium vaccae ATCC 15483 against "Western"-style diet-induced weight gain and visceral adiposity in adolescent male mice., PMID:39709061
Bioinformatics for the Identification of STING-Related Genes in Diabetic Retinopathy., PMID:39704112
Network pharmacology integrated with molecular docking and molecular dynamics simulations to explore the mechanism of Shaoyao Gancao Tang in the treatment of asthma and irritable bowel syndrome., PMID:39686413
Discovery, Validation and Mechanistic Study of XPO1 Inhibition in the Treatment of Triple-Negative Breast Cancer., PMID:39682167
Deciphering the pharmacological mechanism of Radix astragali for allergic rhinitis through network pharmacology and experimental validation., PMID:39622883
Single nuclear RNA sequencing and analysis of basal cells in pulmonary acute respiratory distress syndrome., PMID:39622393
Dietary Influence on Growth, Physicochemical Stability, and Antimicrobial Mechanisms of Antimicrobial Peptides in Black Soldier Fly Larvae., PMID:39590471
Overexpression of ALKBH5 alleviates LPS induced neuroinflammation via increasing NFKBIA., PMID:39571266
Hypoxic and Acidic Tumor Microenvironment-Driven AVL9 Promotes Chemoresistance of Pancreatic Ductal Adenocarcinoma via the AVL9-IκBα-SKP1 Complex., PMID:39566663
MicroRNA-668-3p Mediates Macrophage M2 Polarization by Targeting NFKBIA to Affect Gastric Cancer Cell Proliferation and Migration., PMID:39505541
Transcriptome analysis of the cytokine storm-related genes among the subtypes of idiopathic multicentric Castleman disease., PMID:39462545
The active ingredient of Evodia rutaecarpa reduces inflammation in knee osteoarthritis rats through blocking calcium influx and NF-κB pathway., PMID:39434543
Integrating GWAS and transcriptomics to identify candidate genes conferring relative growth rate trait in white-feathered broiler., PMID:39426221
Bioinformatics data combined with single-cell analysis reveals patterns of immunoinflammatory infiltration and cell death in melanoma., PMID:39418727
Copper aggravated synaptic damage after traumatic brain injury by downregulating BNIP3-mediated mitophagy., PMID:39415457
Different expression patterns of inflammation-related genes and serum microRNAs in young-onset ischemic stroke., PMID:39394477
Evaluation and the mechanism of ShengXian and JinShuiLiuJun decoction in the treatment of silicotic fibrosis: An integrated network pharmacology, life omics, and experimental validation study., PMID:39369919
For research use only. Not for human or drug use.
