Catalog No.
RHJ55402
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
IP, WB
Recommended Dilution
| Application |
Dilution |
| IP |
1:100-1:200, WB: 1:500-1:1000 |
Target
hCARD9, CARD9, Caspase recruitment domain-containing protein 9
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9H257
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W40
Note
For research use only.
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17., PMID:17450144
Proinflammatory response of immature human dendritic cells is mediated by dectin-1 after exposure to Aspergillus fumigatus germ tubes., PMID:18279049
Phospholipase Cgamma2 is critical for Dectin-1-mediated Ca2+ flux and cytokine production in dendritic cells., PMID:19136564
Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRgamma-Syk-Card9-dependent innate immune activation., PMID:19139169
CARD9 versus CARMA1 in innate and adaptive immunity., PMID:19359218
Th17 cells, Job's syndrome and HIV: opportunities for bacterial and fungal infections., PMID:20543597
Protective role of naturally occurring interleukin-17A-producing γδ T cells in the lung at the early stage of systemic candidiasis in mice., PMID:21875963
β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice., PMID:22328069
Unravelling fungal immunity through primary immune deficiencies., PMID:22818901
Antibody constant region peptides can display immunomodulatory activity through activation of the Dectin-1 signalling pathway., PMID:22952831
RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids., PMID:23064150
Card9 mediates intestinal epithelial cell restitution, T-helper 17 responses, and control of bacterial infection in mice., PMID:23732773
Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy and other primary immunodeficiency diseases help to resolve the nature of protective immunity against chronic mucocutaneous candidiasis., PMID:24240291
Primary immunodeficiencies underlying fungal infections., PMID:24240293
C-type lectin receptors differentially induce th17 cells and vaccine immunity to the endemic mycosis of North America., PMID:24391211
C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation., PMID:25202022
Successful Granulocyte Colony-stimulating Factor Treatment of Relapsing Candida albicans Meningoencephalitis Caused by CARD9 Deficiency., PMID:26658378
Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo., PMID:27032818
A novel PIK3CD C896T mutation detected in bilateral sudden sensorineural hearing loss using next generation sequencing: An indication of primary immunodeficiency., PMID:29937814
Moraxella catarrhalis induces CEACAM3-Syk-CARD9-dependent activation of human granulocytes., PMID:27038042
Oxidized Low-Density Lipoprotein Immune Complex Priming of the Nlrp3 Inflammasome Involves TLR and FcγR Cooperation and Is Dependent on CARD9., PMID:28130494
Card9 mediates susceptibility to intestinal pathogens through microbiota modulation and control of bacterial virulence., PMID:28790160
Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination., PMID:28793349
Spondyloarthritis, Acute Anterior Uveitis, and Fungi: Updating the Catterall-King Hypothesis., PMID:29675414
Caspase recruitment domain-containing protein 9 (CARD9) knockout reduces regional ischemia/reperfusion injury through an attenuated inflammatory response., PMID:29940016
The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure., PMID:30279238
Oral Administration of Human Polyvalent IgG by Mouthwash as an Adjunctive Treatment of Chronic Oral Candidiasis., PMID:30627128
Glycosylation of HIV Env Impacts IgG Subtype Responses to Vaccination., PMID:30781796
First Case of Patient With Two Homozygous Mutations in MYD88 and CARD9 Genes Presenting With Pyogenic Bacterial Infections, Elevated IgE, and Persistent EBV Viremia., PMID:30837984
Malassezia Is Associated with Crohn's Disease and Exacerbates Colitis in Mouse Models., PMID:30850233
CARD9 prevents lung cancer development by suppressing the expansion of myeloid-derived suppressor cells and IDO production., PMID:31008530
Effect of CARD9 Deficiency on Neutrophil-Mediated Host Defense against Pulmonary Infection with Streptococcus pneumoniae., PMID:33020213
Priming with FLO8-deficient Candida albicans induces Th1-biased protective immunity against lethal polymicrobial sepsis., PMID:33154574
Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies., PMID:33548172
Local farming of gut fungi protects against dangerous imports., PMID:33705697
Gut mycobiota modulates antifungal antibody-mediated immunity., PMID:33707767
Anti-TROVE2 Antibody Determined by Immune-Related Array May Serve as a Predictive Marker for Adalimumab Immunogenicity and Effectiveness in RA., PMID:33763493
Decreased Treg Cell and TCR Expansion Are Involved in Long-Lasting Graves' Disease., PMID:33912135
TREM (Triggering Receptor Expressed on Myeloid Cells)-1 Inhibition Attenuates Neuroinflammation via PKC (Protein Kinase C) δ/CARD9 (Caspase Recruitment Domain Family Member 9) Signaling Pathway After Intracerebral Hemorrhage in Mice., PMID:33947214
Contribution of mycobiota to the pathogenesis of spondyloarthritis., PMID:34166798
Genetic Analysis of a Cohort of 275 Patients with Hyper-IgE Syndromes and/or Chronic Mucocutaneous Candidiasis., PMID:34390440
[CARD9 Mutation in a Patient with Candida albicans Meningoencephalitis; A Case Report]., PMID:34666665
CARD9 Mediates Pancreatic Islet Beta-Cell Dysfunction Under the Duress of Hyperglycemic Stress., PMID:35362297
Triptolide promotes autophagy to inhibit mesangial cell proliferation in IgA nephropathy via the CARD9/p38 MAPK pathway., PMID:35733381
A Critical Role for CARD9 in Intestinal Microbiota Modulation and Colorectal Malignancies., PMID:36624940
A unique serum IgG glycosylation signature predicts development of Crohn's disease and is associated with pathogenic antibodies to mannose glycan., PMID:39080486
Deletion of Card9 eliminates the detrimental facets of mycobacterial adjuvants., PMID:39386804
The importance of Fcγ and C-type lectin receptors in host immune responses during Pneumocystis pneumonia., PMID:39745390
For research use only. Not for human or drug use.
