Catalog No.
RHH81905
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Applications
ELISA, FCM, IHC
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000 |
Target
Transmembrane protein 119, OBIF, Osteoblast induction factor, TMEM119
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q4V9L6
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3U82
Note
For research use only.
Interaction of Tmem119 and the bone morphogenetic protein pathway in the commitment of myoblastic into osteoblastic cells., PMID:22579779
New tools for studying microglia in the mouse and human CNS., PMID:26884166
Preclinical development of a humanized neutralizing antibody targeting HGF., PMID:28336956
Distinct microglia profile in Creutzfeldt-Jakob disease and Alzheimer's disease is independent of disease kinetics., PMID:30318820
A novel Tmem119-tdTomato reporter mouse model for studying microglia in the central nervous system., PMID:31604143
Immunofluorescence Staining Using IBA1 and TMEM119 for Microglial Density, Morphology and Peripheral Myeloid Cell Infiltration Analysis in Mouse Brain., PMID:31710033
Occurrence of Transmembrane Protein 119 in the Retina is Not Restricted to the Microglia: An Immunohistochemical Study., PMID:31853425
TMEM119 as a specific marker of microglia reaction in traumatic brain injury in postmortem examination., PMID:32719959
Transcriptome of microglia reveals a species-specific expression profile in bovines with conserved and new signature genes., PMID:33811399
High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory disease., PMID:34311763
Quantitative evidence of suppressed TMEM119 microglial immunohistochemistry in fatal morphine intoxications., PMID:34553260
Ventricular opening and cerebrospinal fluid circulation accelerate the biodegradation process of carmustine wafers suggesting their immunomodulation potential in the human brain., PMID:35802230
Density of TMEM119-positive microglial cells in postmortem cerebrospinal fluid as a surrogate marker for assessing complex neuropathological processes in the CNS., PMID:35821334
Characteristics of activation of monocyte-derived macrophages versus microglia after mouse experimental intracerebral hemorrhage., PMID:37113078
HSP27 induced glaucomatous damage in mice of young and advanced age., PMID:37744880
Multiple-Pathway Synergy Alters Steroidogenesis and Spermatogenesis in Response to an Immunocastration Vaccine in Goat., PMID:38201210
Early involvement of peripherally derived monocytes in inflammation in an NMO-like mouse model., PMID:38216632
Tmem119 expression is downregulated in a subset of brain metastasis-associated microglia., PMID:38308250
Differential Roles of Macrophages and Microglia in Subretinal Fibrosis Secondary to Neovascular Age-Related Macular Degeneration., PMID:40111356
Trem2 regulates microglial migratory responses via type I interferon signaling during photoreceptor degeneration., PMID:40468324
For research use only. Not for human or drug use.
