Catalog No.
RHG97902
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
IHC
Recommended Dilution
| Application |
Dilution |
| IHC |
1:200-1:1000 |
Target
SUZ12, Polycomb protein SUZ12, Joined to JAZF1 protein, CHET9, KIAA0160, ChET 9 protein, Suppressor of zeste 12 protein homolog, Chromatin precipitated E2F target 9 protein, JJAZ1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q15022
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T47
Note
For research use only.
The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation., PMID:15916951
An improved cloning strategy for chromatin-immunoprecipitation-derived DNA fragments., PMID:16647032
Suz12 binds to silenced regions of the genome in a cell-type-specific manner., PMID:16751344
Early loss of Xist RNA expression and inactive X chromosome associated chromatin modification in developing primordial germ cells., PMID:17848991
CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop., PMID:18662993
SUZ12 is a candidate target of the non-canonical WNT pathway in the progression of chronic myeloid leukemia., PMID:19847889
Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells., PMID:20064925
Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36., PMID:20150217
Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors., PMID:22193719
Polycomb repressive complex 2 targets murine cytomegalovirus chromatin for modification and associates with viral replication centers., PMID:22279536
Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells., PMID:23588203
Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement., PMID:24186140
Molecular characterization of a population-based series of endometrial stromal sarcomas in Kuwait., PMID:25288234
Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer., PMID:25652097
Loss of H3K27me3 Expression Is a Highly Sensitive Marker for Sporadic and Radiation-induced MPNST., PMID:26645727
PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation., PMID:28285903
WT1 influences apoptosis and proliferation of immature mice granular cells through regulation of the wnt/β-catenin signal pathway., PMID:31880532
Dual targeting of EZH2 and androgen receptor as a novel therapy for castration-resistant prostate cancer., PMID:32805266
Interplay between desmoglein2 and hypoxia controls metastasis in breast cancer., PMID:33431674
Loss of Histone H3K27 Trimethylation (H3K27me3) Expression as a Potential Diagnostic Pitfall in Sarcomatoid Carcinoma., PMID:37997394
For research use only. Not for human or drug use.
