Catalog No.
RHG84501
Species reactivity
Human, Mouse, Rat
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
IHC: 1:50-1:100
Target
Cell migration-inducing gene 19 protein, 1A13B, Next to BRCA1 gene 1 protein, M17S2, KIAA0049, Protein 1A1-3B, Membrane component chromosome 17 surface marker 2, NBR1, Neighbor of BRCA1 gene 1 protein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q14596
Applications
IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3T26
Parvimonas micra promotes oral squamous cell carcinoma metastasis through TmpC-CKAP4 axis., PMID:40055343
Cleavage of the selective autophagy receptor NBR1 by the PDCoV main protease NSP5 impairs autophagic degradation of the viral envelope protein., PMID:40047225
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267
Deciphering melanophagy: role of the PTK2-ITCH-MLANA-OPTN cascade on melanophagy in melanocytes., PMID:39477686
Cleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins., PMID:39128850
CCDC50 mediates the clearance of protein aggregates to prevent cellular proteotoxicity., PMID:38869076
Enteric coronavirus nsp2 is a virulence determinant that recruits NBR1 for autophagic targeting of TBK1 to diminish the innate immune response., PMID:38597182
Tumor-associated macrophage-derived exosomes LINC01592 induce the immune escape of esophageal cancer by decreasing MHC-I surface expression., PMID:37915049
Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation., PMID:37315142
Tumor-Associated Macrophage-Derived Exosomal LINC01232 Induces the Immune Escape in Glioma by Decreasing Surface MHC-I Expression., PMID:37097629
Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity., PMID:36779599
TRAF6 autophagic degradation by avibirnavirus VP3 inhibits antiviral innate immunity via blocking NFKB/NF-κB activation., PMID:35266845
Vitamin D - A host directed autophagy mediated therapy for tuberculosis., PMID:33039674
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1., PMID:32543276
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I., PMID:32376951
Disruptions of Autophagy in the Rat Retina with Age During the Development of Age-Related-Macular-Degeneration-like Retinopathy., PMID:31569675
Emerging views of mitophagy in immunity and autoimmune diseases., PMID:30951392
Proteasome inhibition boosts autophagic degradation of ubiquitinated-AGR2 and enhances the antitumor efficiency of bevacizumab., PMID:30647455
Biochemical Methods to Monitor Autophagic Responses in Plants., PMID:28237117
Autophagy Is an Innate Mechanism Associated with Leprosy Polarization., PMID:28056107
Evaluation of selected binding domains for the analysis of ubiquitinated proteomes., PMID:23649778
Autophagy-related proteins (p62, NBR1 and LC3) in intranuclear inclusions in neurodegenerative diseases., PMID:22728060
NBR1 is a new PB1 signalling adapter in Th2 differentiation and allergic airway inflammation in vivo., PMID:20808283
CA125 velocity at relapse is a highly significant predictor of survival post relapse: results of a 5-year follow-up survey to a randomized placebo-controlled study of maintenance oregovomab immunotherapy in advanced ovarian cancer., PMID:18481390
Antigen-specific immunotherapy of cervical and ovarian cancer., PMID:18363994
Design of a bifunctional fusion protein for ovarian cancer drug delivery: single-chain anti-CA125 core-streptavidin fusion protein., PMID:17257818
Site-specific conjugation of bifunctional chelator BAT to mouse IgG1 Fab' fragment., PMID:16412275
Immunological treatment of ovarian cancer., PMID:15128013
Solution structure of the SEA domain from the murine homologue of ovarian cancer antigen CA125 (MUC16)., PMID:14764598
Clinical and technical evaluation of the ACS:OV serum assay and comparison with three other CA125-detecting assays., PMID:14629806
For research use only. Not for human or drug use.
