Catalog No.
YHD61101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile22-Asn247
Predicted molecular weight
27.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23946
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CMA1, Alpha-chymase, CYH, Chymase, Mast cell protease I, CYM
Salt Stress Leads to Morphological and Transcriptional Changes in Roots of Pumpkins (Cucurbita spp.)., PMID:40508347
Dynactin subunit 1 facilitates mast cell degranulation to drive food allergy pathogenesis., PMID:40404107
Exploring Renin-angiotensin System Genes as Novel Prognostic Biomarkers for Oral Squamous Cell Carcinoma., PMID:40386053
A Comprehensive Analysis of Chemical Composition and Anti-Inflammatory Effects of Cassava Leaf Extracts in Two Varieties in Manihot esculenta Crantz., PMID:40362388
Association of (TG)n(GA)m repeats downstream CMA1 gene with preeclampsia in Mexican population., PMID:40199686
Activation of aryl hydrocarbon receptor ameliorates degranulation of LL-37 induced mast cells in rosacea through enhancing autophagy., PMID:39736238
Degradomics defines proteolysis information flow from human knee osteoarthritis cartilage to matched synovial fluid and the contributions of secreted proteases ADAMTS5, MMP13 and CMA1 to articular cartilage breakdown., PMID:39293776
Inducible pluripotent stem cells to study human mast cell trajectories., PMID:39038754
[Investigation of the immune profile of multiple myeloma patients achieving long-term survival after autologous stem cell transplantation]., PMID:38561281
Genetic Variations Related to Angiotensin II Production and Risk for Basal Cell Carcinoma., PMID:38546913
Urinary metabolic profiles during Helicobacter pylori eradication in chronic gastritis., PMID:38414611
Angiotensinogen, Angiotensin-Converting Enzyme, and Chymase Gene Polymorphisms as Biomarkers for Basal Cell Carcinoma Susceptibility., PMID:37525041
Recombinant SARS-CoV-2 Spike Protein Stimulates Secretion of Chymase, Tryptase, and IL-1β from Human Mast Cells, Augmented by IL-33., PMID:37298438
Analysis of human lung mast cells by single cell RNA sequencing., PMID:37063885
Association Between a High Gene Expression Variant of Chymase and Increased Risk for Basal Cell Carcinoma., PMID:36288866
Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation., PMID:36225927
Combining network pharmacology, RNA-seq, and metabolomics strategies to reveal the mechanism of Cimicifugae Rhizoma - Smilax glabra Roxb herb pair for the treatment of psoriasis., PMID:35963195
Adverse roles of mast cell chymase-1 in COPD., PMID:35777766
Investigation into the Health Effects of Reduced Chymase Function Using Predicted Loss-of-Function Mutations in CMA1., PMID:35513594
Insights into Early-Pregnancy Mechanisms: Mast Cells and Chymase CMA1 Shape the Phenotype and Modulate the Functionality of Human Trophoblast Cells, Vascular Smooth-Muscle Cells and Endothelial Cells., PMID:35406722
Early life adversity drives sex-specific anhedonia and meningeal immune gene expression through mast cell activation., PMID:35339629
Single-cell RNA sequencing of mast cells in eosinophilic esophagitis reveals heterogeneity, local proliferation, and activation that persists in remission., PMID:35304158
Comparative systeomics to elucidate physiological differences between CHO and SP2/0 cell lines., PMID:35228567
Immunoprofiling Reveals Novel Mast Cell Receptors and the Continuous Nature of Human Lung Mast Cell Heterogeneity., PMID:35058936
Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis., PMID:35008966
Increase in Chymase-Positive Mast Cells in Recurrent Pleomorphic Adenoma and Carcinoma Ex Pleomorphic Adenoma of the Parotid Gland., PMID:34884420
Elevated salivary activity of mast cell chymase of periodontitis patients, and a new bradykinin generation cascade, mediating the cross-talks between mast cell and gingival fibroblast., PMID:34688137
Thymol ameliorates 5-fluorouracil-induced intestinal mucositis: Evidence of down-regulatory effect on TGF-β/MAPK pathways through NF-κB., PMID:34665902
Revisiting the renin-angiotensin system., PMID:33819521
Newly developed radioimmunoassay for Human Angiotensin-(1-12) measurements in plasma and urine., PMID:33798634
Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma., PMID:33784348
New inducible mast cell-deficient mouse model (Mcpt5/Cma1DTR)., PMID:33725574
Bacterial and Fungal Toll-Like Receptor Activation Elicits Type I IFN Responses in Mast Cells., PMID:33643293
Exploring the origin and regulatory role of mast cells in asthma., PMID:33369571
The Angiotensin-(1-12)/Chymase axis as an alternate component of the tissue renin angiotensin system., PMID:33309638
Histamine-dependent interactions between mast cells, glia, and neurons are altered following early-life adversity in mice and humans., PMID:32996781
Systems Pharmacology Dissection of Mechanisms of Dengzhan Xixin Injection against Cardiovascular Diseases., PMID:32879224
Identification of SCARA5 Gene as a Potential Immune-Related Biomarker for Triple-Negative Breast Cancer by Integrated Analysis., PMID:32816580
Higher Mast Cell Accumulation in Human Adipose Tissues Defines Clinically Favorable Obesity Sub-Phenotypes., PMID:32575785
Differential Expression of the Angiotensin-(1-12)/Chymase Axis in Human Atrial Tissue., PMID:32361612
Mast cell chymase promotes angiogenesis and lymphangiogenesis mediated by activation of melanoma inhibitory activity gene family members in oral squamous cell carcinoma., PMID:32319583
Association between chymase gene polymorphisms and atrial fibrillation in Chinese Han population., PMID:31888494
Identification of Candidate Biomarkers and Analysis of Prognostic Values in Oral Squamous Cell Carcinoma., PMID:31681590
Calming Down Mast Cells with Ketotifen: A Potential Strategy for Multiple Sclerosis Therapy?, PMID:31463682
Mast cells drive IgE-mediated disease but might be bystanders in many other inflammatory and neoplastic conditions., PMID:31369803
Targeting cholecystokinin-2 receptor for pancreatic cancer chemoprevention., PMID:31313401
Sex differences in gene expression in response to ischemia in the human left ventricular myocardium., PMID:30649309
Mast cell chymase degrades fibrinogen and fibrin., PMID:30561017
Extended cleavage specificities of mast cell proteases 1 and 2 from golden hamster: Classical chymase and an elastolytic protease comparable to rat and mouse MCP-5., PMID:30521603
Mast cell derived carboxypeptidase A3 is decreased among patients with advanced coronary artery disease., PMID:29512095
For research use only. Not for human or drug use.
