Catalog No.
RHG32004
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Applications
ELISA, FCM
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:10000, FCM: 1:200-1:400 |
Target
N-methyl D-aspartate receptor subtype 2A, NMDAR2A, Glutamate [NMDA] receptor subunit epsilon-1, hNR2A, NR2A, Glutamate receptor ionotropic, NMDA 2A, GRIN2A, GluN2A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q12879
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3R89
Note
For research use only.
Short-term consequences of N-methyl-D-aspartate excitotoxicity in rat magnocellular nucleus basalis: effects on in vivo labelling of cholinergic neurons., PMID:11738498
NMDA receptors and PSD-95 are found in attachment plaques in cerebellar granular layer glomeruli., PMID:11876787
Functional expression of distinct NMDA channel subunits tagged with green fluorescent protein in hippocampal neurons in culture., PMID:11897109
Constitutive expression of heterologous N-methyl-D-aspartate receptor subunits in rat adrenal medulla., PMID:11933047
N-Methyl-D-aspartate receptor subunit expression in GnRH neurons changes during reproductive senescence in the female rat., PMID:12193572
Neuropsychiatric disturbances in SLE are associated with antibodies against NMDA receptors., PMID:15804272
Intracerebroventricular administration of ouabain to rats changes the expression of NMDA receptor subunits in cerebral cortex and hippocampus., PMID:19322657
A 9-year-old boy in a confused, sleepy state., PMID:19968190
NMDA-complexes linked to spatial memory performance in the Barnes maze in CD1 mice., PMID:21377497
Role of endoplasmic reticulum stress in the amygdaloid kindling model of rats., PMID:21604154
[Roles and expressions of the NMDA receptor subunits (NR2A and NR2B) in visual cortex area of kittens with the normal visual development and anisometropic amblyopia]., PMID:21604481
Immunolocalization of NR1, NR2A, and PSD-95 in rat hippocampal subregions during postnatal development., PMID:21719075
Antibody-mediated targeted gene transfer of helper virus-free HSV-1 vectors to rat neocortical neurons that contain either NMDA receptor 2B or 2A subunits., PMID:21885042
Association of GRIN1 and GRIN2A-D with schizophrenia and genetic interaction with maternal herpes simplex virus-2 infection affecting disease risk., PMID:21919190
Mass spectrometrical identification of hippocampal NMDA receptor subunits NR1, NR2A-D and five novel phosphorylation sites on NR2A and NR2B., PMID:22335236
Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro., PMID:22486492
α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) and N-methyl-D-aspartate (NMDA) receptors adopt different subunit arrangements., PMID:23760273
Pathological reorganization of NMDA receptors subunits and postsynaptic protein PSD-95 distribution in Alzheimer's disease., PMID:24156266
[Melanoma: from molecular studies to the treatment breakthrough]., PMID:24341237
NMDA reduces Tau phosphorylation in rat hippocampal slices by targeting NR2A receptors, GSK3β, and PKC activities., PMID:24349798
Crucial role of calbindin-D28k in the pathogenesis of Alzheimer's disease mouse model., PMID:24853300
Clustering of surface NMDA receptors is mainly mediated by the C-terminus of GluN2A in cultured rat hippocampal neurons., PMID:25015063
Differential alterations of neocortical GluN receptor subunits in patients with mixed subcortical ischemic vascular dementia and Alzheimer's disease., PMID:25261450
Hippocampal receptor complexes paralleling LTP reinforcement in the spatial memory holeboard test in the rat., PMID:25639541
Anti-NR2A/B Antibodies and Other Major Molecular Mechanisms in the Pathogenesis of Cognitive Dysfunction in Systemic Lupus Erythematosus., PMID:25955648
A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling., PMID:26027736
Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons., PMID:26266540
Integrative neuroscience approach to neuropsychiatric lupus., PMID:26467973
Immunity and Inflammation in Epilepsy., PMID:26684336
Dysfunction of the blood-cerebrospinal fluid-barrier and N-methyl-D-aspartate glutamate receptor antibodies in dementias., PMID:28176002
Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation., PMID:28232581
Understanding the Antibody Repertoire in Neuropsychiatric Systemic Lupus Erythematosus and Neuromyelitis Optica Spectrum Disorder: Do They Share Common Targets?, PMID:29073350
NMDA Receptor Autoantibodies in Autoimmune Encephalitis Cause a Subunit-Specific Nanoscale Redistribution of NMDA Receptors., PMID:29949761
Alpha-synuclein targets GluN2A NMDA receptor subunit causing striatal synaptic dysfunction and visuospatial memory alteration., PMID:30927362
Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory., PMID:32179753
Immunotherapy in GRIN2A-negative Landau-Kleffner Syndrome., PMID:32441907
Highly expressed Claudin18.2 as a potential therapeutic target in advanced gastric signet-ring cell carcinoma (SRCC)., PMID:33457012
Clinical application of trio-based whole-exome sequencing in idiopathic generalized epilepsy., PMID:36842888
Novel mechanisms of Anshen Dingzhi prescription against PTSD: Inhibiting DCC to modulate synaptic function and inflammatory responses., PMID:38848974
[Significance of immunological markers in patients with obstructive sleep apnea and comorbid pathology]., PMID:39269296
Assembly and architecture of endogenous NMDA receptors in adult cerebral cortex and hippocampus., PMID:39855198
For research use only. Not for human or drug use.
