Catalog No.
YHD56301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn68-Ser280
Predicted molecular weight
26.36 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23276
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Kell blood group glycoprotein, KEL, CD238
A structure-based in silico analysis of the Kell blood group system., PMID:39726599
Genetic profile of RHCE, Kell, Duffy, Kidd, Diego and MNS hybrid glycophorins blood groups in ethnic northeastern Thais: Alleles, genotypes and risk of alloimmunisation., PMID:38804163
Epigenetic dissection of human blood group genes reveals regulatory elements and detailed characteristics of KEL and four other loci., PMID:38644556
Use of KEL-1 negative red blood cells for emergency release., PMID:37563839
A novel KEL c.1414-1G>T allele in a polish patient with anti-Ku antibody., PMID:35932201
Novel KEL allele associated with loss of Kpb identified in a white blood donor., PMID:35852066
Noninvasive diagnostics of fetal KEL*01.01 allele from maternal plasma of immunized women using digital PCR protocols., PMID:35191535
Functional Evaluation of KEL as an Oncogenic Gene in the Progression of Acute Erythroleukemia., PMID:35140839
Recognizing Impaired Decisional Capacity in Vaccine Refusal: Reply to Kels and Kels., PMID:35120287
Novel KEL*02M allele in Austria encoding a Kmod phenotype., PMID:34910313
Five novel silenced KEL*02 alleles., PMID:34554576
A novel KEL null allele with c.223+1g>t leads to the absence of the Kpb antigen in a First Nation donor., PMID:34310722
Complement Plays a Critical Role in Inflammation-Induced Immunoprophylaxis Failure in Mice., PMID:34249009
Novel KEL*02N allele in Saudi Arabia encoding a Kell null (K0 ) phenotype., PMID:34137046
[Expression of circ-KEL in acute myeloid leukemia and its regulatory mechanisms in leukemic cells]., PMID:33910309
HLA-DRB1 molecules and the presentation of anchor peptides from RhD, RhCE, and KEL proteins., PMID:33675036
An open-source python library for detection of known and novel Kell, Duffy and Kidd variants from exome sequencing., PMID:33567470
The effectiveness of KEL and RHCE fetal genotype assessment in alloimmunized women by minisequencing., PMID:33562967
Diversity of variant alleles encoding Kidd, Duffy, and Kell antigens in individuals with sickle cell disease using whole genome sequencing data from the NHLBI TOPMed Program., PMID:33231305
Poly(I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice., PMID:32266378
Association between HLA-DRB1*01 and HLA-DRB1*15 with alloimmunisation in transfusion-dependent patients with thalassaemia., PMID:32227529
Do red cell alloantibodies continue to challenge breast fed babies?, PMID:32083382
Low incidence of post-transfusion Kell (KEL1) alloimmunisation in patients under 50 years old., PMID:31769076
Establishment of KEL*01 and KEL*02 Genotyping to Recruit Uncommon, Kell-positive, Reagent Red Cells Among Thai Blood Donors., PMID:31625357
First report of a KELnull phenotype in Peru and a lesson of invisible genetic disparity., PMID:31176642
A novel c.1664G > T(p.Gly555Val) mutation in the KEL gene encoding the Kmod phenotype., PMID:31077392
Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation., PMID:30578106
Complement serves as a switch between CD4+ T cell-independent and -dependent RBC antibody responses., PMID:30429364
Transfused platelets enhance alloimmune responses to transfused KEL-expressing red blood cells in a murine model., PMID:30418129
Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies., PMID:29445378
Silent KEL alleles identified from Japanese individuals with the Ko phenotype., PMID:29280152
Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin., PMID:28871080
Antigen Density Dictates Immune Responsiveness following Red Blood Cell Transfusion., PMID:28250159
Three new alleles encoding an apparent Kellnull phenotype., PMID:27861976
An innovative test for non-invasive Kell genotyping on circulating fetal DNA by means of the allelic discrimination of K1 and K2 antigens., PMID:27730708
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice., PMID:27688803
Effect of Irradiation on Microparticles in Red Blood Cell Concentrates., PMID:27139610
New KEL*01M and KEL*02M alleles: structural modeling to assess the impact of amino acid changes., PMID:26996808
Clinically significant anti-KEL RBC alloantibodies are transferred by breast milk in a murine model., PMID:26950259
Riboflavin-ultraviolet light pathogen reduction treatment does not impact the immunogenicity of murine red blood cells., PMID:26643781
Clinical Potential of Effective Noninvasive Exclusion of KEL1-Positive Fetuses in KEL1-Negative Pregnant Women., PMID:26492079
NON-INVASIVE MONITORING OF FOETAL ANAEMIA IN KELL SENSITIZED PREGNANCY., PMID:26411147
Kell and Kx blood group systems., PMID:26308465
Anti-KEL sera prevents alloimmunization to transfused KEL RBCs in a murine model., PMID:26185172
The prevalence of anti-K in Canadian prenatal patients., PMID:25968929
Acute extravascular hemolytic transfusion reaction due to anti-Kpa antibody missed by electronic crossmatch., PMID:25175412
Novel alleles at the Kell blood group locus that lead to Kell variant phenotype in the Dutch population., PMID:25156717
Provision of KEL1-negative blood to obstetric patients: a 3-year single-institution retrospective review., PMID:25118004
Three missense mutations found in the KEL gene lead to K(mod) or K0 red blood cell phenotypes., PMID:25041236
For research use only. Not for human or drug use.
