Catalog No.
RHF90002
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:200-1:1000, WB: 1:500-1:2000
Target
Octamer-binding protein 4, Oct-4, OCT3, OCT4, OTF3, OTF-3, Octamer-binding transcription factor 3, POU5F1, Oct-3, POU domain, class 5, transcription factor 1, Octamer-binding protein 3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q01860
Applications
FCM, IF, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3Q46
Pluripotent stem cell marker deficiency in salivary mucoepidermoid carcinoma with relevance to molecular profiling: An experimental study., PMID:40478494
A dual-Color closed bipolar electrochemiluminescence platform for visual simultaneous diagnosis of two pluripotency markers in cancer patients' urine., PMID:40253801
Myoepithelial tumors of soft tissue and bone in children and young adults: A clinicopathologic study of 40 cases occurring in patients ≤ 21 Years of age., PMID:38782103
Prostate cancer research: tools, cell types, and molecular targets., PMID:38595814
[Effect of Human Bone Marrow Mesenchymal Stem Cells with Ectopic High OCT4 Expression on T Lymphocyte Function]., PMID:37846711
Causal associations between prodromal infection and neuromyelitis optica spectrum disorder: A Mendelian randomization study., PMID:37540821
Analysis of N-glycosylation protein of Kashin-Beck disease chondrocytes derived from induced pluripotent stem cells based on label-free strategies with LC-MS/MS., PMID:37186116
Oct4 reduction contributes to testicular injury of unilateral testicular torsion in mice model and apoptotic death of Sertoli cells through mediating CIP2A expression., PMID:36690227
A non-metabolic function of hexokinase 2 in small cell lung cancer: promotes cancer cell stemness by increasing USP11-mediated CD133 stability., PMID:35975322
Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2., PMID:35777358
POU5F1 Protein and Gene Expression Analysis in Neonate and Adult Mouse Testicular Germ Cells by Immunohistochemistry and Immunocytochemistry., PMID:34788058
Exon and intron sharing in opposite direction-an undocumented phenomenon in human genome-between Pou5f1 and Tcf19 genes., PMID:34610795
Targeted mass spectrometry for monitoring of neural differentiation., PMID:34357391
Expression of SSEA-4 and Oct-4 from somatic cells in primary mouse gastric cell culture induced by brief strong acid., PMID:33733429
Generation of Systemic Lupus Erythematosus Patient-Derived Induced Pluripotent Stem Cells from Blood., PMID:33397195
Breast tumour cell subpopulations with expression of the MYC and OCT4 proteins., PMID:33037978
Isolation, identification and differentiation of human spermatogonial cells on three-dimensional decellularized sheep testis., PMID:32992121
Posttranscriptional regulation of maternal Pou5f1/Oct4 during mouse oogenesis and early embryogenesis., PMID:32930837
Oct4 promotes M2 macrophage polarization through upregulation of macrophage colony-stimulating factor in lung cancer., PMID:32487125
MYC transcription activation mediated by OCT4 as a mechanism of resistance to 13-cisRA-mediated differentiation in neuroblastoma., PMID:32409685
Detection of circulating natural antibodies against CD25, MUC1, and VEGFR1 for early diagnosis of non-small cell lung cancer., PMID:32392378
Targeted sequencing reveals the mutational landscape responsible for sorafenib therapy in advanced hepatocellular carcinoma., PMID:32373219
OCT4 immunohistochemistry after staging laparoscopic retroperitoneal lymphadenectomy for testicular tumor., PMID:31819332
Humanized Stem Cell Models of Pediatric Medulloblastoma Reveal an Oct4/mTOR Axis that Promotes Malignancy., PMID:31786016
Mass cytometry-based single-cell analysis of human stem cell reprogramming uncovers differential regulation of specific pluripotency markers., PMID:31570522
Expression of Components of the Renin-Angiotensin System by the Embryonic Stem Cell-Like Population within Keloid Lesions., PMID:31348346
Targeting of replicating CD133 and OCT4/SOX2 expressing glioma stem cells selects a cell population that reinitiates tumors upon release of therapeutic pressure., PMID:31267022
Hypermethylation of microRNA-149 activates SDF-1/CXCR4 to promote osteogenic differentiation of mesenchymal stem cells., PMID:31206187
Differentiation of spermatogonial stem cells by soft agar three-dimensional culture system., PMID:31131631
Postnatal germ cell development during first 18 months of life in testes from boys with non-syndromic cryptorchidism and complete or partial androgen insensitivity syndrome., PMID:30739749
Establishment and characterization of human theca stem cells and their differentiation into theca progenitor cells., PMID:30132968
Generation of Transplantable Retinal Pigmented Epithelial (RPE) Cells for Treatment of Age-Related Macular Degeneration (AMD)., PMID:29896658
Mapping transcription factor occupancy using minimal numbers of cells in vitro and in vivo., PMID:29572359
Characterization of migratory primordial germ cells in the aorta-gonad-mesonephros of a 4.5-week-old human embryo: a toolbox to evaluate in vitro early gametogenesis., PMID:29528446
[Ewing sarcomas and Ewing-like sarcomas : New aspects]., PMID:29480450
Effects of prostaglandin E2 on clonogenicity, proliferation and expression of pluripotent markers in human periodontal ligament cells., PMID:28763754
OCT4 controls mitotic stability and inactivates the RB tumor suppressor pathway to enhance ovarian cancer aggressiveness., PMID:28319064
The serine 106 residue within the N-terminal transactivation domain is crucial for Oct4 function in mice., PMID:28264735
Tissue organization alters gene expression in equine induced trophectoderm cells., PMID:28161437
New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells., PMID:28009074
Enhanced expression of the stemness-related factors OCT4, SOX15 and TWIST1 in ectopic endometrium of endometriosis patients., PMID:27881125
Identification of miRSNPs associated with the risk of multiple myeloma., PMID:27718532
Primary Mediastinal Yolk Sac Tumors: An Immunohistochemical Analysis of 14 Cases., PMID:27643524
Positive Oct -3/4 and D2-40 Immunohistochemical Expression in Germ Cells and Suspected Histology Pattern of Intratubular Germ Cell Neoplasia in Boys with Cryptorchidism Vanish after the Age of 2 Years., PMID:27606906
Arsenite inhibits the function of CD133+ CD13+ liver cancer stem cells by reducing PML and Oct4 protein expression., PMID:27517564
Characterization of the POU5F1 Homologue in Nile Tilapia: From Expression Pattern to Biological Activity., PMID:27473876
Conservation of spermatogonial stem cell marker expression in undifferentiated felid spermatogonia., PMID:27129396
High-resolution telomere fluorescence in situ hybridization reveals intriguing anomalies in germ cell tumors., PMID:27085557
WNT/β-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary., PMID:26939755
Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer., PMID:28798885
For research use only. Not for human or drug use.
