Catalog No.
YHD49601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val510-Val750
Predicted molecular weight
28.50 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22033
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MMUT, Methylmalonyl-CoA mutase, mitochondrial, MUT, Methylmalonyl-CoA isomerase, MCM
New genetic tools to define the pathophysiology of inborn errors of cobalamin metabolism impacting mammalian development., PMID:40411980
Cyst fluid proteins stratify malignant risk of intraductal papillary mucinous neoplasm of the pancreas., PMID:40300662
Isolated methylmalonic acidemia in Mexico: Genotypic spectrum, report of two novel MMUT variants and a possible synergistic heterozygosity effect., PMID:39494389
Long-term follow-up of Chinese patients with methylmalonic acidemia of the cblC and mut subtypes., PMID:39306609
Improved therapeutic efficacy in two mouse models of methylmalonic acidemia (MMA) using a second-generation mRNA therapy., PMID:39121792
A Noble Metal Substitution Leads to B12 Cofactor Mimicry by a Rhodibalamin., PMID:39012171
Integrated analysis of genomics and transcriptomics revealed the genetic basis for goaty flavor formation in goat milk., PMID:38823464
[Clinical features and follow-up study on 55 patients with adolescence-onset methylmalonic acidemia]., PMID:38763872
A novel MMUT splicing variant causing mild methylmalonic acidemia phenotype., PMID:38455531
Searching for homozygous haplotype deficiency in Manech Tête Rousse dairy sheep revealed a nonsense variant in the MMUT gene affecting newborn lamb viability., PMID:38424485
Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation., PMID:38271099
Genetic analysis of isolated methylmalonic acidemia in Henan, China: c.1663G>A variant of MMUT prevalent in the Henan population., PMID:38128819
Screening of 1.17 million newborns for inborn errors of metabolism using tandem mass spectrometry in Shanghai, China: A 19-year report., PMID:38061323
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair., PMID:37468522
Biomarkers to predict disease progression and therapeutic response in isolated methylmalonic acidemia., PMID:37243446
Effect of source and amount of rumen-protected choline on hepatic metabolism during induction of fatty liver in dairy cows., PMID:37210357
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair., PMID:36993209
Incidence and genetic variants of inborn errors of metabolism identified through newborn screening: A 7-year study in eastern coastal areas of China., PMID:36787440
The complex machinery of human cobalamin metabolism., PMID:36680553
Novel AAV-mediated genome editing therapy improves health and survival in a mouse model of methylmalonic acidemia., PMID:36126056
Impaired Function of a Rare Mutation in the MMUT Gene Causes Methylmalonic Acidemia in a Chinese Patient., PMID:35919035
Growth advantage of corrected hepatocytes in a juvenile model of methylmalonic acidemia following liver directed adeno-associated viral mediated nuclease-free genome editing., PMID:35868241
[Genetic analysis of 21 cases of methylmalonic acidemia]., PMID:35446966
The genotype analysis and prenatal genetic diagnosis among 244 pedigrees with methylmalonic aciduria in China., PMID:35361390
Investigation and Analysis of Blood Biochemical Indexes and Molecular Biology of Methylmalonic Acidemia., PMID:35254044
Genetic pleiotropy between pulmonary function and age-related traits: The Long Life Family Study., PMID:35180297
Effect of Mutations in GvpJ and GvpM on Gas Vesicle Formation of Halobacterium salinarum., PMID:34975818
Spectrum and characterization of bi-allelic variants in MMAB causing cblB-type methylmalonic aciduria., PMID:34796408
Clinical characteristics of advanced non-small cell lung cancer patients with EGFR exon 20 insertions., PMID:34548567
Benefits and Risks of Iron Interventions in Infants in Rural Bangladesh., PMID:34496174
Decrease of disease-related metabolites upon fasting in a hemizygous knock-in mouse model (Mut-ko/ki) of methylmalonic aciduria., PMID:33728246
A Transparent Approach to Calculate Detection Rate and Residual Risk for Carrier Screening., PMID:33349347
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia., PMID:32976669
Proteinuria as a presenting sign of combined methylmalonic acidemia and homocysteinemia: case report., PMID:32957924
Do the circulating Pre-S/S quasispecies influence hepatitis B virus surface antigen levels in the HBeAg negative phase of HBV infection?, PMID:32390175
Methylmalonyl acidemia: from mitochondrial metabolism to defective mitophagy and disease., PMID:32316822
Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency., PMID:32080200
In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria., PMID:31770620
Tricarboxylic acid cycle enzyme activities in a mouse model of methylmalonic aciduria., PMID:31648943
The morphology and composition of influenza A virus particles are not affected by low levels of M1 and M2 proteins in infected cells., PMID:15919950
Testing hypotheses about determinants of protein structure with high-precision, high-throughput stability measurements and statistical modeling., PMID:12809516
For research use only. Not for human or drug use.
