Catalog No.
YHD49101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly52-Pro271
Predicted molecular weight
26.63 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21964
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Catechol O-methyltransferase, COMT
Ontogeny of catechol-o-methyltransferase expression in the rat prefrontal cortex: effects of methamphetamine exposure., PMID:40451167
Temporomandibular joint disorders, happiness, and COMT, HTR2A and FKBP5 polymorphisms in adolescents: a cross-sectional study., PMID:40435063
A comprehensive analysis of the O-methyltransferase gene family in the chili pepper (Capsicum annuum) identifies COMT36 involved in capsaicinoids biosynthesis., PMID:40379172
The Intersection of Genetics and Neuroimaging: A Systematic Review of Imaging Genetics in Neurological Disease for Personalized Treatment., PMID:40360788
ABCB1, SLC22A1, COMT, and OPRM1 genotypes: Study of their influence on plasma methadone levels and clinical response to methadone maintenance treatment in opioid use disorder., PMID:40346879
Do Single-Nucleotide Polymorphisms Affect Pain Intensity and Sufentanil Analgesia After Pediatric Scoliosis Correction Surgery?, PMID:40331998
Association of Lower COMT Activity Alleles with Aggressive Traits in Male Youth with Conduct Disorder Living in a Correctional Facility., PMID:40305338
Transcriptomics-proteomics analysis reveals StCOMT1 regulates drought, alkali and combined stresses in potato., PMID:40299051
Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review., PMID:40222694
Computational analysis of the structural-functional dynamics of a Co-receptor proteoglycan., PMID:40201239
Identification of a COMT Gene Involved in the Biosynthesis of Melatonin Which Mediates Resistance to Citrus Canker., PMID:40172092
Identification of Therapeutic Potential of Hydroxychavicol Against Alzheimer's Disease: An Integrated Network Pharmacology, Molecular Docking, and Dynamic Simulation Study., PMID:40170792
The ABF4-bHLH28-COMT5 module regulates melatonin synthesis and root development for drought tolerance in citrus., PMID:40089838
Genetic determinants of longitudinal behavioural trajectories in rare conditions: The case of fragile X syndrome., PMID:40054504
Exploring Potential Drug Targets in Multiple Cardiovascular Diseases: A Study Based on Proteome-Wide Mendelian Randomization and Colocalization Analysis., PMID:40026415
Evidence of COMT dysfunction in the olfactory bulb in Parkinson's disease., PMID:40024917
PtrVINV2 is dispensable for cellulose synthesis but essential for salt tolerance in Populus trichocarpa Torr. and Gray., PMID:39992899
A translational perspective of the malignant hematopoietic proteoglycome., PMID:39980017
Jasmonic acid and nitric oxide orchestrate a hierarchical melatonin cascade for Botrytis cinerea resistance in tomato., PMID:39977124
Caffeic acid O-methyltransferase-dependent flavonoid defenses promote sorghum resistance to fall armyworm infestation., PMID:39970129
Melatonin confers saline-alkali tolerance in tomato by alleviating nitrosative damage and S-nitrosylation of H+-ATPase 2., PMID:39928568
Pre-harvest application of forchlorfenuron enhances fruit quality and bioactive substance accumulation in Chunhua loquat., PMID:39879758
Pharmacogenetic Testing for Predicting Methylphenidate Treatment Outcomes in Childhood Attention Deficit Hyperactivity Disorder in Turkey: Focus on Carboxylesterase 1, Latrophilin-3, and Catechol-O-Methyltransferase., PMID:39868802
Comparative response mechanisms of two cultivars of Musa paradisiaca L. to Fusarium oxysporum f.sp. cubense infection., PMID:39850207
Pharmacogenetic Testing in Treatment-resistant Panic Disorder: a Preliminary Analysis., PMID:39839219
The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome., PMID:39810946
Genetic variants in COMT and ESR1 genes shape treatment response to raloxifene in schizophrenia-spectrum disorders., PMID:39799793
Exogenous Melatonin Boosts Heat Tolerance in Rosa hybrida via RhCOMT1 Modulation., PMID:39795289
Genotypic Influences on Actuators of Aerobic Performance in Tactical Athletes., PMID:39766802
Association of COMT rs4680 Genotype With Chronic Neuropathic Pain Experience in Patients With Sickle Cell Disease., PMID:39734110
Molecular Biomarkers Associated with Traumatic Brain Injury Outcome in Individuals of Black Racial Identity or African Ancestry: A Narrative Review., PMID:39732452
Multisubstrate-based system: a kinetic mechanism study of catechol-O-methyltransferase., PMID:39726140
[Interaction between COMT gene polymorphisms and childhood trauma in adolescents with non-suicidal self-injury]., PMID:39725396
GENETIC VARIANTS IN ANTIPSYCHOTIC METABOLISM: POLYMORPHISM PROFILES IN KAZAKH COHORT WITH PARANOID SCHIZOPHRENIA., PMID:39724888
Genome Assembly and Winged Fruit Gene Regulation of Chinese Wingnut: Insights from Genomic and Transcriptomic Analyses., PMID:39666952
Cognitive impairment in patients with melanoma before adjuvant immune checkpoint inhibitor therapy and associations with brain gray matter, catechol-O-methyltransferase genotype, and psychological factors., PMID:39663713
Personalized nutrition and precision medicine in perimenopausal women: A minireview of genetic polymorphisms COMT, FUT2, and MTHFR., PMID:39642577
GhCOMT33D modulates melatonin synthesis, impacting plant response to Cd2+ in cotton via ROS., PMID:39641144
COMT Val158Met polymorphism protects the impact of a mother's history of childhood trauma on emotional and behavioural problems in preschool children., PMID:39631778
Lifespan longitudinal changes in mesocortical thickness and executive function: Role of dopaminergic genetic predisposition., PMID:39613505
Comparative transcriptomic and proteomic analyses of two salt-tolerant alfalfa (Medicago sativa L.) genotypes: investigation of the mechanisms underlying tolerance to salt., PMID:39606676
The moderating role of COMT gene rs4680 polymorphism between maladaptive metacognitive beliefs and negative symptoms in patients with schizophrenia., PMID:39567927
Genomic factors associated with substance use disorder relapse: A critical review., PMID:39553284
Critical evaluation of the current landscape of pharmacogenomics in Parkinson's disease - What is missing? A systematic review., PMID:39551668
A genome-wide association study in Swedish colorectal cancer patients with gastric- and prostate cancer in relatives., PMID:39543761
Muscle Weakness in an Adult With 22q11.2 Deletion Syndrome., PMID:39496467
Genetic polymorphisms and bruxism: A scoping review., PMID:39490028
The Critical Role of Phenylpropanoid Biosynthesis Pathway in Lily Resistance Against Gray Mold., PMID:39456848
Different risk and protective factors predict change of planning ability in middle versus older age., PMID:39455694
Genome-Wide Identification of COMT Gene Family in Maize and its Function in Response to Light., PMID:39443412
For research use only. Not for human or drug use.
