Catalog No.
YHD46601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Trp27-Ser549
Predicted molecular weight
60.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21589
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD73, 5'-nucleotidase, NT5E, NT5, 5'-NT, Ecto-5'-nucleotidase, NTE
Caffeinated and Decaffeinated Yerba Mate (Ilex paraguariensis) Infusion Extracts Alter CD73 and Reduce the Migration and Adhesion of Glioblastoma Cells., PMID:40512339
Evaluation of CD73, PD-1, circHIPK3, and circNRIP1 expression in the peripheral blood of patients with colorectal cancer., PMID:40505000
CD73-expressing endometrial regenerative cell-derived exosomes mitigate acute cardiac allograft rejection through regulating adenosine metabolism in mice., PMID:40457389
Innovating Glioma Therapy Using Secretions from Umbilical Cord Mesenchymal Stem Cells to Target Homeobox and Growth Factor Genes., PMID:40421391
Research progress of CD73-adenosine signaling regulating hepatocellular carcinoma through tumor microenvironment., PMID:40420185
The cytotoxic effect of quercetin-induced apoptosis on lung metastatic cells from giant cell tumor of bone., PMID:40418557
Discovery of Orally Potent Small-Molecule CD73 Inhibitor for Cancer Immunotherapy., PMID:40409990
Acyclic purine and pyrimidine nucleotide analogs as ecto-5'-nucleotidase (CD73) inhibitors., PMID:40378575
Region-specific neuroprotective effects of meldonium pretreatment in two models of sepsis-associated encephalopathy., PMID:40371344
Assessing Ecto-5'-Nucleotidase/CD73 Expression and Malignancy Parameters in Early- and Late- Passage C6 Glioma Cells., PMID:40366422
Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration., PMID:40356987
Lysophosphatidylcholine negatively reverses the effects of human umbilical cord-derived mesenchymal stem cells on high glucose-induced cell dysfunction., PMID:40351154
Rapamycin Reduces Arterial Mineral Density and Promotes Beneficial Vascular Remodeling in a Murine Model of Severe Medial Arterial Calcification., PMID:40338175
Combination of Epigallocatechin-3-Gallate and Tramiprosate Prevent Accumulation of Intracellular Aβ and Dysfunctional Autophagy-Lysosomal Pathway at Earliest Stage of Transdifferentiation of Mesenchymal Stromal Cells into PSEN1 E280A Cholinergic-like Neurons., PMID:40332390
Adenosine signaling in promoting the balance between erythropoiesis and myelopoiesis., PMID:40314242
Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells., PMID:40305498
Derivation of Mesenchymal Stem Cells through Sequential Presentation of Growth Factors via Gelatin Microparticles in Pluripotent Stem Cell Spheroids., PMID:40303481
Inhibition of M2 macrophage-mediated mesenchymal stem cell migration: Boldine attenuates elbow heterotopic ossification., PMID:40287052
Regulatory T Cell Mimicry by a Subset of Mesenchymal GBM Stem Cells Suppresses CD4 and CD8 Cells., PMID:40277917
Expression of the TIGIT axis and the CD39/CD73 purinergic pathway in bone metastasis-derived immune cells., PMID:40274631
Immune-activated microspheres for enhanced chemoembolization of hepatocellular carcinoma by blocking the adenosine A2A receptor., PMID:40274057
Autophagy inhibition enhances antifibrotic potential of placental mesenchymal stem cells of fetal origin via regulating TGF-β1 mediated protein degradation of HGF., PMID:40258831
Human mesenchymal stem cell expansion on laminin-521 in serum-free and xeno-free culture conditions., PMID:40249103
PD1+ T Regulatory Cells Are Not Sufficient to Protect from Gestational Hypertension., PMID:40243452
Evaluation of hepatic cancer stem cells (CD73+, CD44+, and CD90+) induced by diethylnitrosamine in male rats and treatment with biologically synthesized silver nanoparticles., PMID:40232523
MGAT1-Guided complex N-Glycans on CD73 regulate immune evasion in triple-negative breast cancer., PMID:40229283
Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection., PMID:40222009
Tumor-Derived CD109 Orchestrates Reprogramming of Tumor-Associated Macrophages to Dampen Immune Response., PMID:40220905
RUNX1 is a key inducer of human hematopoiesis controlling non-hematopoietic mesodermal development., PMID:40220285
Human umbilical cord mesenchymal stem cells improve the pregnancy outcomes of preeclampsia rats via inducing placental angiogenesis., PMID:40213878
CD73low B-cell phenotypes and distinct cytokine profiles in patients with active anti-Jo-1 antibody positive idiopathic inflammatory myopathies., PMID:40210261
Adenosine-generating CD39+ plasmablasts predispose to successful infliximab therapy in pediatric IBD., PMID:40199584
Assessing the impact of CD73 inhibition on overcoming anti-EGFR resistance in glioma cells., PMID:40191718
Pretreatment of stem cells from human exfoliated deciduous teeth with low dosage of chrysin induces autophagy and cell survival as a target in regenerative therapy., PMID:40187007
Evaluation of Novel Therapeutic Agents for Modulation of the Inflammatory Response in Rotator Cuff Tendinopathy Utilizing a Mouse Model of Subacromial Impingement., PMID:40159684
Influence of the Breast Tumor Stromal Fibroblasts on Immunological Processes In Vitro., PMID:40156744
TGF-β Induces the Secretion of Extracellular Vesicles Enriched with CD39 and CD73 from Cervical Cancer Cells., PMID:40141056
CD73 Molecule Inhibitor Upregulates miR16 Expression in Experimental Glioblastoma and Inhibits Angiogenesis by Targeting VEGF., PMID:40140182
LuQi formula ameliorates pressure overload-induced heart failure by regulating macrophages and regulatory T cells., PMID:40118747
CD73: a new immune checkpoint for leukemia treatment., PMID:40114928
Increased primary breast tumor expression of CD73 is associated with development of bone metastases and is a potential biomarker for adjuvant bisphosphonate use., PMID:40108234
Development of CD73 Inhibitors in Tumor Immunotherapy and Opportunities in Imaging and Combination Therapy., PMID:40106690
The effects of nanocurcumin on immune-related factors in the ankylosing spondylitis patients: a double-blind, randomized, placebo-controlled clinical trial., PMID:40106064
Stromal Cell Subsets Show Model-Dependent Changes in Experimental Colitis and Affect Epithelial Tissue Repair and Immune Cell Activation., PMID:40100003
Novel anti-CD73-IL-2v bispecific fusion protein augments antitumor immunity by alleviating immunosuppressive adenosine pathways in CD8+ T cells., PMID:40081940
Comprehensive Analysis of High-Sensitive Flow Cytometry and Molecular Mensurable Residual Disease in Philadelphia Chromosome-Positive Acute Leukemia., PMID:40076750
EZH2 coordinates memory B-cell programming and recall responses., PMID:40073167
Activin A activation of Smad3 mitigates innate inflammation in mouse models of psoriasis and sepsis., PMID:40067393
Adapting radiation therapy to immunotherapy: Delineation and treatment planning of pre-operative immune-modulating breast iSBRT in 151 patients treated in the randomized phase II Neo-CheckRay trial., PMID:40057199
Effects and mechanisms of breastmilk stem cells in the treatment of white matter injury in newborn rats., PMID:40055828
For research use only. Not for human or drug use.
