Catalog No.
RHE13203
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Applications
IHC, IP, WB
Recommended Dilution
| Application |
Dilution |
| IHC |
1:50-1:250, IP: 1:100-1:200, WB: 1:500-1:1000 |
Target
NMMHC-IIA, Non-muscle myosin heavy chain IIa, Cellular myosin heavy chain, type A, Myosin heavy chain 9, NMMHC II-a, Non-muscle myosin heavy chain A, Myosin-9, MYH9, NMMHC-A, Myosin heavy chain, non-muscle IIa
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P35579
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3J79
Note
For research use only.
Heavy chain myosin 9-related disease (MYH9 -RD): neutrophil inclusions of myosin-9 as a pathognomonic sign of the disorder., PMID:20174760
In vitro expression and characterization of MYH9 mutant alleles linked to hereditary hearing loss., PMID:20416459
[Differential diagnosis and treatment of thrombocytopenia]., PMID:20941473
Nonmuscle myosin IIA is required for lamellipodia formation through binding to WAVE2 and phosphatidylinositol 3,4,5-triphosphate., PMID:21184743
A notable case report of May-Hegglin anomaly with immune complex-related nephropathy: a genetic and histological analysis., PMID:21329637
May-Hegglin anomaly in a dog., PMID:21554370
Genetics of proteinuria: an overview of gene mutations associated with nonsyndromic proteinuric glomerulopathies., PMID:21782134
Mouse models of MYH9-related disease: mutations in nonmuscle myosin II-A., PMID:21908426
International collaboration as a tool for diagnosis of patients with inherited thrombocytopenia in the setting of a developing country., PMID:22672365
Collapsing glomerulopathy associated lupus in a black female with homozygous APOL1 mutation., PMID:22952321
PRBC-derived plasma induces non-muscle myosin type IIA-mediated neutrophil migration and morphologic change., PMID:23083320
Autoimmunity and cystatin SA1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type 1., PMID:23122533
Clinical, pathological, and genetic analysis of ten patients with MYH9-related disease., PMID:23207509
May-Hegglin anomaly and pregnancy: a systematic review., PMID:23811802
Close relations between podocyte injuries and membranous proliferative glomerulonephritis in autoimmune murine models., PMID:23817053
Congenital thrombocytopenia with nephritis - The first case of MYH9 related disorder in Serbia., PMID:24783421
[Recent progress in platelet laboratory testing]., PMID:25297771
Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia., PMID:25395423
Rituximab induced psoriasis in an infant., PMID:25424224
Genetic susceptibility to idiopathic membranous nephropathy in high-prevalence Area, Taiwan., PMID:25520922
Successful Kidney Transplantation in Epstein Syndrome With Antiplatelet Antibodies and Donor-specific Antibodies: A Case Report., PMID:26518967
Late onset and high-frequency dominant hearing loss in a family with MYH9 disorder., PMID:26942920
MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection., PMID:27112594
THE EFFECT OF LYSOPHOSPHATIDIC ACID ON THE COMPOSITION OF MYOSIN-9 AND TROPOMYOSIN CONTAINING CYTOPLASMIC PROTEIN COMPLEXES., PMID:30199160
Efficacy of neutrophil non-muscle myosin heavy chain-IIA immunofluorescence analysis in determining the pathogenicity of MYH9 variants., PMID:28293712
Diagnosis of inherited platelet disorders on a blood smear: a tool to facilitate worldwide diagnosis of platelet disorders., PMID:28457011
TRPV4 mediates the Ca2+ influx required for the interaction between flightless-1 and non-muscle myosin, and collagen remodeling., PMID:28526784
Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits., PMID:30086768
Proteome-transcriptome analysis and proteome remodeling in mouse lens epithelium and fibers., PMID:30359574
Cell surface expression of HLA I molecules as a marker of young platelets., PMID:31207003
MYH9-related disorders display heterogeneous kidney involvement and outcome., PMID:31384440
MYH9 overexpression correlates with clinicopathological parameters and poor prognosis of epithelial ovarian cancer., PMID:31423165
Next-generation sequencing for the diagnosis of MYH9-RD: Predicting pathogenic variants., PMID:31562665
The use of pan-retinal photocoagulation to treat recurrent vitreous haemorrhage with neovascularisation in the context of Epstein syndrome: an MYH9-related disorder., PMID:31888892
MYH9 Key Amino Acid Residues Identified by the Anti-Idiotypic Antibody to Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 5 Involve in the Virus Internalization by Porcine Alveolar Macrophages., PMID:31905776
A novel de novo MYH9 mutation in MYH9-related disease: A case report and review of literature., PMID:31977897
Diagnosis of Inherited Platelet Disorders on a Blood Smear., PMID:32079152
Antibodies in cerebral cavernous malformations react with cytoskeleton autoantigens in the lesional milieu., PMID:32362501
Immunoglobulin A nephropathy in a patient with an MYH9 -related disorder., PMID:34383333
4H12, a Murine Monoclonal Antibody Directed against Myosin Heavy Chain-9 Expressed on Acinar Cell Carcinoma of Pancreas with Potential Therapeutic Application., PMID:34425650
circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating the Wnt/beta-catenin pathway., PMID:34450253
Myosin Heavy Chain 9 (MYH9)-Related Congenital Macrothrombocytopenia., PMID:34527454
Identification of MYH9 Key Domain Involved in the Entry of PRRSV Into Permissive Cells., PMID:35694306
Renal injury associated with MYH9 disorder with 5773delG mutation: A case report., PMID:36602281
Successful administration of eltrombopag in preparation for peritoneal dialysis catheter placement in a girl with MYH9-related disease., PMID:37000325
Amino acids 1811-1960 of myosin heavy chain 9 is involved in murine gammaherpesvirus 68 infection., PMID:37515945
Aggregates of nonmuscular myosin IIA in erythrocytes associate with GATA1- and GFI1B-related thrombocytopenia., PMID:38103735
Antibody MYH9 and Antibiotic Lidamycin Inhibit the Growth and Proliferation of Lung Cancer Cells and Induce Their Apoptosis., PMID:38997500
Monoclonal Antibodies Targeting Porcine Macrophages Are Able to Inhibit the Cell Entry of Macrophage-Tropic Viruses (PRRSV and ASFV)., PMID:40006922
Hepatocyte-specific C-C motif chemokine ligand 9 signaling promotes liver fibrosis progression in mice., PMID:40359088
For research use only. Not for human or drug use.
