Catalog No.
YHD43801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro403-Leu596
Predicted molecular weight
24.94 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20936
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RasGAP, Ras GTPase-activating protein 1, Ras p21 protein activator, GTPase-activating protein, p120GAP, RASA, GAP, RASA1
A Cross-Sectional Exploratory Study of Rat Sarcoid (Ras) Activation in Women with and Without Polycystic Ovary Syndrome., PMID:40072105
The C2 domain augments Ras GTPase-activating protein catalytic activity., PMID:39899710
The significance of exosomal non-coding RNAs (ncRNAs) in the metastasis of colorectal cancer and development of therapy resistance., PMID:39643147
Variations in RASA1 and EPHB4 in Chinese patients with capillary malformation-arteriovenous malformation., PMID:39578666
Second Report of the p.Leu874Pro Missense Variant in EPHB4 in a Family With Capillary Malformation-Arteriovenous Malformation Syndrome (CM-AVM) Syndrome., PMID:39431828
EPHB4-RASA1 Inhibition of PIEZO1 Ras Activation Drives Lymphatic Valvulogenesis., PMID:39421925
Genotypes and phenotypes of capillary malformation-arteriovenous malformation: characterization and correlation analysis., PMID:39367533
5q14.3 Microdeletion Syndrome With Simultaneous Involvement of MEF2C and RASA1. Clinical Case and Review of the Literature., PMID:39258307
Another face of RASA1: Report of familial germline variant in RASA1 with dysmorphic features., PMID:38934655
K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins., PMID:38858602
SHP2-EGFR States in Dephosphorylation Can Inform Selective SHP2 Inhibitors, Dampening RasGAP Action., PMID:38747619
LncRNA XIST Protects Against Polycystic Ovary Syndrome via the Regulation of miR-212-3p/RASA1 Axis., PMID:38609670
Measurement of KRAS-GTPase Activity., PMID:38570454
Single dominant lesion in capillary malformation-arteriovenous malformation (CM-AVM) RASA1 syndrome., PMID:38556785
Activation of MAP Kinase Pathway by Polyisoprenylated Cysteinyl Amide Inhibitors Causes Apoptosis and Disrupts Breast Cancer Cell Invasion., PMID:38540084
Nigella sativa, Anthemis hyaline and Citrus sinensis extracts reduce SARS-CoV-2 replication by fluctuating Rho GTPase, PI3K-AKT, and MAPK/ERK pathways in HeLa-CEACAM1a cells., PMID:38485035
Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation., PMID:38275291
The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells., PMID:38202644
An EPHB4-RASA1 signaling complex inhibits shear stress-induced Ras-MAPK activation in lymphatic endothelial cells to promote the development of lymphatic vessel valves., PMID:38045382
p120 RasGAP and ZO-2 are essential for Hippo signaling and tumor-suppressor function mediated by p190A RhoGAP., PMID:37995182
Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations., PMID:37978175
miR-182/183-Rasa1 axis induced macrophage polarization and redox regulation promotes repair after ischemic cardiac injury., PMID:37801856
Network Pharmacology-Based Identification of Key Pharmacological Mechanism of Shen-qi-di-huang Decoction Acting on Uremia., PMID:37773677
Spectrum of lymphatic anomalies in patients with RASA1-related CM-AVM., PMID:37767822
Clear Cell Squamous Cell Carcinoma of the Maxillary Gingiva Associated with PIK3CA and HRAS Mutations: Report of a Case and Literature Review., PMID:37735286
Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency., PMID:37730636
rasa1-related arteriovenous malformation is driven by aberrant venous signalling., PMID:37708300
Fully accessible fitness landscape of oncogene-negative lung adenocarcinoma., PMID:37695905
Temporospatial inhibition of Erk signaling is required for lymphatic valve formation., PMID:37691058
Lymphatic Malformations in Parkes Weber's Syndrome: Retrospective Review of 16 Cases in a Vascular Anomalies Center., PMID:37595632
Diverse p120RasGAP interactions with doubly phosphorylated partners EphB4, p190RhoGAP, and Dok1., PMID:37507023
A temporally-restricted pattern of endothelial cell collagen 4 alpha 1 expression during embryonic development determined with a novel knockin Col4a1-P2A-eGFP mouse line., PMID:37501352
Clinical and auxological characteristics and quality of life of 50 children and adolescents with segmental overgrowth syndromes at a single center., PMID:37471470
Identification of prognosis value and immune microenvironment features of ceRNAs in NSCLC with distinct gene mutation., PMID:37390335
EPHB4-RASA1-Mediated Negative Regulation of Ras-MAPK Signaling in the Vasculature: Implications for the Treatment of EPHB4- and RASA1-Related Vascular Anomalies in Humans., PMID:37259315
Kechuanning Gel Plaster Exerts Anti-inflammatory and Immunomodulatory Effects on Ovalbumin-induced Asthma Model Rats via ERK Pathway., PMID:37138476
Combined Hepatocellular-Cholangiocarcinoma With Ductal Plate Malformation Pattern: A Case Report With Molecular Analysis., PMID:37128663
A review on the role of SNHG8 in human disorders., PMID:37043963
Prenatal Clinical Findings in RASA1-Related Capillary Malformation-Arteriovenous Malformation Syndrome., PMID:36980822
Investigation into the genetics of fetal congenital lymphatic anomalies., PMID:36959127
High-depth next-generation sequencing panel testing in the evaluation of arteriovenous malformations., PMID:36924216
Genetic Profile of Arteriovenous Anomalies of the Head and Neck: Implications in Progression and Therapeutic Approaches., PMID:36868957
MEG3 sponges miRNA-376a and YBX1 to regulate angiogenesis in ovarian cancer endothelial cells., PMID:36747515
Genetic testing in the evaluation of individuals with clinical diagnosis of atypical Sturge-Weber syndrome., PMID:36710374
Fetal Hydrothorax Treated with Pleuro-Amniotic Shunting: Fetal and Maternal Complications and Long-Term Outcomes., PMID:36709748
Germline genetic mutations in pediatric cerebrovascular anomalies: a multidisciplinary approach to screening, testing, and management., PMID:36681951
Mutational analysis of microsatellite-stable gastrointestinal cancer with high tumour mutational burden: a retrospective cohort study., PMID:36681091
Synaptoproteomic Analysis of the Prefrontal Cortex Reveals Spatio-Temporal Changes in SYNGAP1 Following Cannabinoid Exposure in Rat Adolescence., PMID:36614142
Identification of ferroptosis-related genes and pathways in diabetic kidney disease using bioinformatics analysis., PMID:36585417
Delivery of a peptide/microRNA blend via electrospun antimicrobial nanofibres for wound repair., PMID:36334906
For research use only. Not for human or drug use.
