Catalog No.
YHD42701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp19-Ser182
Predicted molecular weight
21.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20827
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EPLG1, EFNA1, LERK1, Immediate early response protein B61, EPH-related receptor tyrosine kinase ligand 1, TNFAIP4, TNF alpha-induced protein 4, LERK-1, Ephrin-A1, Tumor necrosis factor alpha-induced protein 4
The RNA-Binding Proteins MCPIP2 and IGF2BP1 Competitively Modulate Breast Tumor Angiogenesis by Antagonizing VEGFA mRNA Stability and Expression., PMID:40354028
EPHRIN-A1 and -A2 act as positive growth factors for developing spiral ganglion radial bundles., PMID:40345476
Cellular communication networks in fibrosis: Insights from the MASLD pig model., PMID:40304567
Competitive inhibition of Ephrin-A1 and EphA2 binding by Perillaldehyde leads to decreased TRPM2 expression and reduced mitochondrial damage in vascular endothelial cells., PMID:40288150
Role of EFNAs in Shaping the Tumor Immune Microenvironment and Their Impact on Pancreatic Adenocarcinoma Prognosis., PMID:40190415
Differential association of EphA2 intracellular regions in biased signaling., PMID:40049409
Genetic Variants in RASSF1 (rs2073498), SERPINE1 (rs1799889), and EFNA1 (rs12904) Are Associated with Susceptibility in Mexican Patients with Colorectal Cancer: Clinical Associations and Their Analysis In Silico., PMID:40004552
Super-enhancer-driven EFNA1 fuels tumor progression in cervical cancer via the FOSL2-Src/AKT/STAT3 axis., PMID:39964764
Regulation of inflammatory responses: Harnessing the Ruan Mai Jian targeting of EphA2/ephrinA1 pathway to enhance atherosclerosis amelioration., PMID:39842373
Ephrin A1 functions as a ligand of EGFR to promote EMT and metastasis in gastric cancer., PMID:39838173
The diagnostic value of serum Ephrin-A1 in patients with colorectal cancer., PMID:39732744
Proteome-Wide Mendelian Randomization Analysis to Identify Potential Plasma Biomarkers and Therapeutic Targets for Epithelial Ovarian Cancer Subtypes., PMID:39726690
Proteomics and Incident Kidney Failure in Individuals With CKD: The African American Study of Kidney Disease and Hypertension and the Boston Kidney Biopsy Cohort., PMID:39634331
Phosphatidylinositol 4,5-bisphosphate drives the formation of EGFR and EphA2 complexes., PMID:39630914
Ephrin A1 Stimulates CCL2 Secretion to Facilitate Premetastatic Niche Formation and Promote Gastric Cancer Liver Metastasis., PMID:39412948
Vasculogenic mimicry-related gene prognostic index for predicting prognosis, immune microenvironment in clear cell renal cell carcinoma., PMID:39247316
Discovery of a new 1-(phenylsulfonyl)-1H-indole derivative targeting the EphA2 receptor with antiproliferative activity on U251 glioblastoma cell line., PMID:39024966
Combined detection of serum EFNA1 and MMP13 as diagnostic biomarker for gastric cancer., PMID:38987376
Transcriptomic Analysis of PDCoV-Infected HIEC-6 Cells and Enrichment Pathways PI3K-Akt and P38 MAPK., PMID:38675921
Inhibiting Eph/ephrin signaling reduces vascular leak and endothelial cell dysfunction in mice with sepsis., PMID:38657024
Gene Signature Associated with Nervous System in an Experimental Radiation- and Estrogen-Induced Breast Cancer Model., PMID:38137332
Secreted proteins encoded by super enhancer-driven genes could be promising biomarkers for early detection of esophageal squamous cell carcinoma., PMID:37774793
Urinary Proteomics for Discovery of Gastric Cancer Biomarkers to Enable Precision Clinical Oncology., PMID:37579183
Shared Genetics and Comorbid Genes of Amyotrophic Lateral Sclerosis and Parkinson's Disease., PMID:37534731
Increased Serum EphrinA1 Is Associated with Parenchymal Hematoma after Ischemic Stroke., PMID:37105137
Identification of diagnostic biomarks and immune cell infiltration in ulcerative colitis., PMID:37055577
Peripheral Circulating Exosomal-miRNAs Potentially Mediate the Sensitivity to Interferon Treatment in Chronic Hepatitis B Virus Patients., PMID:36944116
Stigmasterol protects human brain microvessel endothelial cells against ischemia-reperfusion injury through suppressing EPHA2 phosphorylation., PMID:36871980
Pharmacological characterization of second generation FXR agonists as effective EphA2 antagonists: A successful application of target hopping approach., PMID:36792038
May EPH/Ephrin Targeting Revolutionize Lung Cancer Treatment?, PMID:36613532
Proteomics uncover EPHA2 as a potential novel therapeutic target in colorectal cancer cell lines with acquired cetuximab resistance., PMID:36401637
A genome-wide association study with tissue transcriptomics identifies genetic drivers for classic bladder exstrophy., PMID:36352089
Role of EFNA1 SNP (rs12904) in Tumorigenesis and Metastasis of Colorectal Cancer: A Bioinformatic Analysis and HRM SNP Genotyping Verification., PMID:36308379
Single-Cell Transcriptomics of Endothelial Cells in Upper and Lower Human Esophageal Squamous Cell Carcinoma., PMID:36290884
Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney., PMID:36266461
H4 acetylation by the NuA4 complex is required for plastid transcription and chloroplast biogenesis., PMID:36038656
The Functions of EphA1 Receptor Tyrosine Kinase in Several Tumors., PMID:35996244
The efficacy of receptor tyrosine kinase EphA2 autophosphorylation increases with EphA2 oligomer size., PMID:35970390
Nintedanib Alleviates Experimental Colitis by Inhibiting CEBPB/PCK1 and CEBPB/EFNA1 Pathways., PMID:35910380
Exosomal EPHA2 derived from highly metastatic breast cancer cells promotes angiogenesis by activating the AMPK signaling pathway through Ephrin A1-EPHA2 forward signaling., PMID:35673569
EFNA1 in gastrointestinal cancer: Expression, regulation and clinical significance., PMID:35646281
Determination of WWOX Function in Modulating Cellular Pathways Activated by AP-2α and AP-2γ Transcription Factors in Bladder Cancer., PMID:35563688
Competition for shared downstream signaling molecules establishes indirect negative feedback between EGFR and EphA2., PMID:35430415
The Pan-Cancer Crosstalk Between the EFNA Family and Tumor Microenvironment for Prognosis and Immunotherapy of Gastric Cancer., PMID:35309935
An integrated analysis of single-cell and bulk transcriptomics reveals EFNA1 as a novel prognostic biomarker for cervical cancer., PMID:35072898
NuA4 and H2A.Z control environmental responses and autotrophic growth in Arabidopsis., PMID:35022409
The Expression of ephrinA1/ephA2 Receptor Increases in Chronic Rhinosinusitis and ephrinA1/ephA2 Signaling Affects Rhinovirus-Induced Innate Immunity in Human Sinonasal Epithelial Cells., PMID:34975898
Eph signaling is regulated by miRNA-210: Implications for corneal epithelial repair., PMID:34856019
Modulation of the Host Cell Transcriptome and Epigenome by Fusobacterium nucleatum., PMID:34700376
A review on the role of different ephrins in glioma., PMID:34688637
For research use only. Not for human or drug use.
